Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sandra Rex-Rabe"'
Autor:
Haiying Tang, Jiahui Li, Bradley Zinker, Stephanie Boehm, Amy Mauer, Sandra Rex‐Rabe, Kevin J. Glaser, Matthew Fronheiser, Thomas Bradstreet, Yasuhiko Nakao, Thomas Petrone, Adrienne Pena, MacKenzie Villano, Patrick Chow, Harmeet Malhi, Edgar D. Charles, Wendy Hayes, Richard L. Ehman, Shuyan Du, Meng Yin
Publikováno v:
Journal of Magnetic Resonance Imaging. 56:712-724
Treatments for nonalcoholic steatohepatitis (NASH) are urgently needed. Hepatic fat fraction and shear stiffness quantified by magnetic resonance imaging (MRI-HFF) and magnetic resonance elastography (MRE-SS), respectively, are biomarkers for hepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b795d0eabae9743581e5bbd47c3ca2
https://doi.org/10.1002/jmri.28077
https://doi.org/10.1002/jmri.28077
Autor:
Jenny Xie, Tracy L. Taylor, Sandra Rex-Rabe, Joel C. Barrish, William J. Pitts, Kim W. McIntyre, Percy H. Carter, Scott H. Watterson, Murray McKinnon, Richard Liu, Bethanne M. Warrack, Suzanne J. Suchard, Mary Ellen Cvijic, Charles M. Langevine, Celia D’Arienzo, S. H. Spergel, Ding Ren Shen, Melissa Yarde, Dana Banas, Georgia Cornelius, Robert V. Moquin, Luisa Salter-Cid, Anthony M. Marino, Kathleen M. Gillooly, David J. Shuster, Praveen Balimane, Junqing Guo, Alaric J. Dyckman
Publikováno v:
Journal of medicinal chemistry. 59(6)
Sphingosine 1-phosphate (S1P) is the endogenous ligand for the sphingosine 1-phosphate receptors (S1P1–5) and evokes a variety of cellular responses through their stimulation. The interaction of S1P with the S1P receptors plays a fundamental physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b442f2b835175b1ee0b7bde5377e100
https://pubmed.ncbi.nlm.nih.gov/26924461
https://pubmed.ncbi.nlm.nih.gov/26924461
Autor:
Alaric J. Dyckman, David J. Shuster, James Kempson, Georgia Cornelius, Sandra Rex-Rabe, Tracy L. Taylor, Kim W. McIntyre, Anthony M. Marino, Percy H. Carter, Junqing Guo, Dana Banas, Celia D’Arienzo, Luisa Salter-Cid, Praveen Balimane, Suzanne J. Suchard, Jenny Xie, Kathleen M. Gillooly, Steven H. Spergel, Mary Ellen Cvijic, William J. Pitts, Scott H. Watterson, Murray McKinnon, Richard Liu, Joel C. Barrish, Charles M. Langevine, Ding Ren Shen, Melissa Yarde
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(10)
The synthesis and structure–activity relationship (SAR) of a series of pyridyl-isoxazole based agonists of S1P1 are discussed. Compound 5b provided potent in vitro activity with selectivity, had an acceptable pharmacokinetic profile, and demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3262618d2b41ca82905ff4092e0e3f0
https://pubmed.ncbi.nlm.nih.gov/27055941
https://pubmed.ncbi.nlm.nih.gov/27055941
Autor:
Steven Grant, Suzanne J. Suchard, Robert P. Rehfuss, Steven G. Nadler, Kathleen M. Gillooly, Anish Suri, Robert Kuhn, Ruth Brosius, Yifan Zhang, Rathna Ravishankar, Kathy A Mink, Aaron P. Yamniuk, Sandra Rex-Rabe, Jenny Xie, Philip Drew, Luisa Salter-Cid, Kimberly S Waggie, James William Bryson, Olga Ignatovich, Lin Cheng, Laura Price, Xiadi Zhou, Yongmi An, James K. Tamura, Virna Borowski, Xiaoxia Yang, Bozena Abramczyk, Vojkan Susulic
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(9)
CD40–CD40L interactions play a critical role in regulating immune responses. Blockade of CD40L by Abs, such as the anti-CD40L Ab 5c8, demonstrated positive clinical effects in patients with autoimmune diseases; however, incidents of thromboembolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f805007657a9cec2f3f88fbe5d1db4e8
https://pubmed.ncbi.nlm.nih.gov/24670803
https://pubmed.ncbi.nlm.nih.gov/24670803