Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sandra R Mirandola"'
Autor:
Barbara Radermacher, Pawel Tacik, Sandra R. Mirandola, Sergio Castro-Gomez, Michael T. Heneka, Patrick Weydt
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Diagnosis, management and therapeutic trials are hampered by a lack of informative biomarkers. Troponin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::696dbac21c3a15b768cf4664f91cf796
https://doi.org/10.1101/2021.02.15.21251783
https://doi.org/10.1101/2021.02.15.21251783
Autor:
Sandra R. Mirandola, Barbara Radermacher, Patrick Weydt, Sergio Castro-Gomez, Michael T. Heneka, Pawel Tacik
Publikováno v:
Brain Communications
Brain communications 3(4), fcab274 (2021). doi:10.1093/braincomms/fcab274
Brain communications 3(4), fcab274 (2021). doi:10.1093/braincomms/fcab274
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Diagnosis, management and therapeutic trials are hampered by a lack of informative biomarkers. Troponins are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e5bd07f613707e3ffe4d4ce86e99d1
https://pubmed.ncbi.nlm.nih.gov/34993474
https://pubmed.ncbi.nlm.nih.gov/34993474
Autor:
Simone Hornemann, Gudrun Engels, Philip M. Hansbro, Matthew Mangan, Christoph Brenker, Terje Espevik, Martin Fricke, Ashraf Al-Amoudi, Bernardo S. Franklin, Andrew G. Jarnicki, Dominic De Nardo, Adriano Aguzzi, Bernadette Jones, Ann Marshak-Rothstein, Patricia Busto, Eicke Latz, Brian G. Monks, Sandra R Mirandola, Lukas Bossaller, Sebastian Zimmer, Andrea Stutz, Mark Nordhoff, Wolfgang Kastenmüller, Jacqueline M Ratter, Reinhold E. Schmidt
Publikováno v:
NATURE IMMUNOLOGY
Nature Immunology
Nature immunology 15(8), 727-737 (2014). doi:10.1038/ni.2913
Nature Immunology
Nature immunology 15(8), 727-737 (2014). doi:10.1038/ni.2913
Microbes or danger signals trigger inflammasome sensors, which induce polymerization of the adaptor ASC and the assembly of ASC specks. ASC specks recruit and activate caspase-1, which induces maturation of the cytokine interleukin 1β (IL-1β) and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c0f177a0bc33d6a2dafccc3a4f5880
https://doi.org/10.1038/ni.2913
https://doi.org/10.1038/ni.2913
Autor:
Carlos Otávio Brandão, Irene Lorand Metze, Dannie Eiko Maeda Hallal-Longo, Fernanda G. Pereira, Elaine C. Oliveira, Leonilda M.B. Santos, Alessandro S. Farias, Benito Pereira Damasceno, Sandra R. Mirandola, Heloisa Helena Ruocco
Publikováno v:
Journal of Interferon & Cytokine Research. 27:865-874
Multiple sclerosis (MS) is a chronic inflammatory disease of the white matter of the central nervous system (CNS) characterized by focal areas of demyelination. Interferon-beta (IFN-beta) provides an effective treatment that lessens the frequency and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a122b1d86a2bbb7ff0bd0a79e97ddd1b
https://doi.org/10.1089/jir.2007.0018
https://doi.org/10.1089/jir.2007.0018
Publikováno v:
Neurochemical Research. 31:541-548
Methylmalonic acidemia (MMAemia) is an inherited metabolic disorder of branched amino acid and odd-chain fatty acid metabolism, involving a defect in the conversion of methylmalonyl-coenzyme A to succinyl-coenzyme A. Systemic and neurological manifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a0bd786e091b829e19998c8312ba11
https://doi.org/10.1007/s11064-006-9054-6
https://doi.org/10.1007/s11064-006-9054-6
Autor:
Helena C. F. Oliveira, Bruno A. Paim, Luciane C. Alberici, Karina G. Zecchin, Sandra R. Mirandola, Roger F. Castilho, Cezar R. Pestana, Anibal E. Vercesi
Publikováno v:
Lipids in Health and Disease
Background We have previously demonstrated that increased rates of superoxide generation by extra-mitochondrial enzymes induce the activation of the mitochondrial ATP-sensitive potassium channel (mitoKATP) in the livers of hypertriglyceridemic (HTG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7368461cc30a210c2a9367ab0522cc
https://pubmed.ncbi.nlm.nih.gov/23764148
https://pubmed.ncbi.nlm.nih.gov/23764148
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2f76298cd14b6cfb72cb93b6612d9c
Autor:
Gábor Zsurka, Claude Jardel, Anne Lombès, Wolfram S. Kunz, Cornelia Kornblum, Sandra R. Mirandola, P. Marcorelles, Kevin G. Hampel, Isabelle Nelson, S. Lavoué, Robert Sassen
Publikováno v:
Neurology. 74(6)
Objective: To present 2 families with maternally inherited severe epilepsy as the main symptom of mitochondrial disease due to point mutations at position 616 in the mitochondrial tRNA Phe ( MT-TF ) gene. Methods: Histologic stainings were performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d20edf514eec206941169538b771f
https://pubmed.ncbi.nlm.nih.gov/20142618
https://pubmed.ncbi.nlm.nih.gov/20142618
Publikováno v:
FEBS letters. 584(10)
Pretreatment of tissues with potassium channel openers (KCO’s) has been observed to be cytoprotective in a broad variety of insults. This phenomenon has been proposed to be intimately linked to activation of mitochondrial potassium channels which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a098aeb19d36684e3c3eaa9102d766d5
https://pubmed.ncbi.nlm.nih.gov/20080090
https://pubmed.ncbi.nlm.nih.gov/20080090
Publikováno v:
Journal of Neuroscience Research.
The adult rat striatum is particularly vulnerable to systemic administration of the succinate dehydrogenase inhibitor 3-nitropropionic acid (3NP), which is known to induce degeneration of the caudate-putamen, as occurs in Huntington's disease. The ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d75c23c29eb2f894c0a05e01e423ecc
https://doi.org/10.1002/jnr.22239
https://doi.org/10.1002/jnr.22239