Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sandra Piquer"'
Autor:
Nuria Palau, Sandra A. Rebuffat, Felicia A. Hanzu, Sandra Piquer, Jordi Altirriba, Ramon Gomis, Albert Barberà
Publikováno v:
Endocrinology. 153:177-187
In obesity an increase in β-cell mass occurs to cope with the rise in insulin demand. This β-cell plasticity is essential to avoid the onset of hyperglycemia, although the molecular mechanisms that regulate this process remain unclear. This study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8884069dbf7f0f2c368bbe4b3224451
https://doi.org/10.1210/en.2011-0181
https://doi.org/10.1210/en.2011-0181
Autor:
Ramon Gomis, Paola Casini, Lisa Cadavez, Jordi Altirriba, Anna Novials, Silvia Casas, Maud Soty, Sandra Piquer
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 299:E1087-E1095
BACE1 (β-site amyloidogenic cleavage of precursor protein-cleaving enzyme 1) is a β-secretase protein that plays a central role in the production of the β-amyloid peptide in the brain and is thought to be involved in the Alzheimer's pathogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24cb76e6cd9243a75bc7657d38cdb05
https://doi.org/10.1152/ajpendo.00420.2010
https://doi.org/10.1152/ajpendo.00420.2010
Autor:
Ana B. Ropero, Miguel A. López-Boado, Everardo M. Carneiro, Sandra Piquer, Eva Tudurí, Ramon Gomis, Ivan Quesada, Angel Nadal, Thiago M. Batista, Sergi Soriano, Laura Marroquí
Publikováno v:
Diabetes
OBJECTIVE Leptin released from adipocytes plays a key role in the control of food intake, energy balance, and glucose homeostasis. In addition to its central action, leptin directly affects pancreatic β-cells, inhibiting insulin secretion, and, thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9709b1a8dd4eae8584ad72e887d9731
https://doi.org/10.2337/db08-1787
https://doi.org/10.2337/db08-1787
Autor:
Sara Bonicchio, Vito Lampasona, Ezio Bonifacio, Cristina Belloni, Sandra Piquer, Roberto Furlan
Publikováno v:
Journal of Immunological Methods. 336:127-134
Autoantibodies, a hallmark of autoimmune disease, are directed against diverse antigens and epitopes. This diversity aids in characterising disease progression and identifying disease-associated autoantibodies. Here we aimed to develop a sensitive as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5818b261f77ec3df3748eb05290c320e
https://doi.org/10.1016/j.jim.2008.04.005
https://doi.org/10.1016/j.jim.2008.04.005
Autor:
Ramon Gomis, Ana-Belén Ropero, Abel López-Bermejo, Iñaki Pérez, Angel Nadal, José Manuel Fernández-Real, Judit Bassols, Roser Casamitjana, Eva Arnaiz, Wifredo Ricart, Sandra Piquer
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 93:2523-2530
Context: Conflicting results on the effects of salicylates on glucose tolerance in subjects with normal glucose tolerance or type 2 diabetes have been reported.Objective: The objective of the study was to investigate the effects of a salicylate deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6bdff4cf88fd31a3e11c80cf93b9d0
https://doi.org/10.1210/jc.2007-1212
https://doi.org/10.1210/jc.2007-1212
Autor:
Marta Julià, Joan J. Guinovart, Sandra Piquer, Belen Nadal, Nuria Marzo, Sílvia Barceló-Batllori, Ramon Gomis
Publikováno v:
Biochemical and Biophysical Research Communications. 358:385-391
Oral administration of sodium tungstate is an effective treatment for diabetes in animal models. Several lines of evidence indicate the pancreatic beta cell as one of the targets of tungstate action. Here, we examined the molecular mechanism by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d839872cbcf15504fcca615ed4cccbbe
https://doi.org/10.1016/j.bbrc.2007.04.143
https://doi.org/10.1016/j.bbrc.2007.04.143
Autor:
Maria Luisa Malosio, Françoise Roquet, Daniel Laune, Tiziana Giordano, Claude Granier, Vito Lampasona, Stéphanie Roche, Ezio Bonifacio, Bénédicte Jardin-Watelet, Lionel Valera, Michael R. Christie, Sandra Piquer
Publikováno v:
Journal of Autoimmunity. 26:215-222
IA-2 and IA-2beta are highly related proteins that are autoantigens in type 1 diabetes, and provide a model for developing reagents and assays that distinguish similar proteins with unique autoantibody epitopes. Monoclonal antibodies (mAb) to IA-2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7513f7c0df9959d6da576792cc318fdc
https://doi.org/10.1016/j.jaut.2005.12.001
https://doi.org/10.1016/j.jaut.2005.12.001
Autor:
Angels Ortiz, Alberto de Leiva, Sandra Piquer, Gemma Badell, Rosa Corcoy, Agueda Caballero, Mercè Albareda
Publikováno v:
Diabetes Care. 26:1199-1205
OBJECTIVE—In Spanish women with gestational diabetes mellitus (GDM), we aimed to study the progression to diabetes and abnormal glucose tolerance (AGT) and identify predictive factors. RESEARCH DESIGN AND METHODS—In 696 women with GDM and 70 cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c81e8deff90f0c18cab475f84a3d6b5
https://doi.org/10.2337/diacare.26.4.1199
https://doi.org/10.2337/diacare.26.4.1199
Autor:
Holger Steinbrenner, Zhidong Ling, Kristian Löbner, Daniel Pipeleers, Jochen Seissler, Michael R. Christie, Guo Cai Huang, Sandra Piquer, Graham A. Roberts
Publikováno v:
Diabetes. 51:2982-2988
IA-2 and phogrin are tyrosine phosphatase-like proteins that may mediate interactions between secretory granules and cytoskeleton in islets and neuroendocrine tissues. We investigated factors that regulate IA-2 and phogrin expression and their relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad53a41c4f439f129139a767104f63a
https://doi.org/10.2337/diabetes.51.10.2982
https://doi.org/10.2337/diabetes.51.10.2982
Autor:
Maria Carmen Carmona, M. Soty, Sílvia Barceló-Batllori, Analía Bortolozzi, Sandra Piquer, Roger R. Gomis, Rosa Gasa, Gemma Pujadas, M. Amigó-Correig
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Aims: Sodium tungstate is an anti-obesity drug targeting peripheral tissues. In vivo, sodium tungstate reduces body weight gain and food intake through increasing energy expenditure and lipid oxidation, but it also modulates hypothalamic gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159125b7a776be41a24cd28c0d9cd308
https://pubmed.ncbi.nlm.nih.gov/21205112
https://pubmed.ncbi.nlm.nih.gov/21205112