Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sandra Pierre"'
Autor:
Maksim Sendetski, Saskia Wedel, Kenta Furutani, Lisa Hahnefeld, Carlo Angioni, Jan Heering, Béla Zimmer, Sandra Pierre, Alexandra-Maria Banica, Klaus Scholich, Sorin Tunaru, Gerd Geisslinger, Ru-Rong Ji, Marco Sisignano
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110552- (2024)
Summary: Noxious stimuli activate nociceptive sensory neurons, causing action potential firing and the release of diverse signaling molecules. Several peptides have already been identified to be released by sensory neurons and shown to modulate infla
Externí odkaz:
https://doaj.org/article/9870422af084425992e7ef7e3feb5b83
Autor:
Joschua Friedel, Sandra Pierre, Anja Kolbinger, Tim J. Schäufele, Blerina Aliraj, Andreas Weigert, Klaus Scholich
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDuring an innate inflammation, immune cells form distinct pro- and anti-inflammatory regions around pathogen-containing core-regions. Mast cells are localized in an anti-inflammatory microenvironment during the resolution of an innate inf
Externí odkaz:
https://doaj.org/article/4946d48705c9429db4fe3838195d2a2b
Autor:
Anja Kolbinger, Tim J Schäufele, Hanna Steigerwald, Joschua Friedel, Sandra Pierre, Gerd Geisslinger, Klaus Scholich
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Pathogen‐induced inflammation comprises pro‐ and anti‐inflammatory processes, which ensure pathogen removal and containment of the proinflammatory activities. Here, we aimed to identify the development of inflammatory microenvironments
Externí odkaz:
https://doaj.org/article/498a7c3b871e4cb6bba74af3f2022d42
Autor:
Erika Dorochow, Nico Kraus, Nicolas Chenaux-Repond, Sandra Pierre, Anja Kolbinger, Gerd Geisslinger, Cristina Ortiz, Christoph Welsch, Jonel Trebicka, Robert Gurke, Lisa Hahnefeld, Sabine Klein, Klaus Scholich
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10351 (2023)
Non-alcoholic steatohepatitis (NASH) and alcoholic steatohepatitis (ASH) are the leading causes of liver disease worldwide. To identify disease-specific pathomechanisms, we analyzed the lipidome, metabolome and immune cell recruitment in livers in bo
Externí odkaz:
https://doaj.org/article/4acf9d0679674ba2ab8d69572f73d6b0
Autor:
Lisa Kornstädt, Sandra Pierre, Andreas Weigert, Stefanie Ebersberger, Tim J. Schäufele, Anja Kolbinger, Tobias Schmid, Jennifer Cohnen, Dominique Thomas, Nerea Ferreirós, Bernhard Brüne, Ingo Ebersberger, Klaus Scholich
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Next to their role in IgE-mediated allergic diseases and in promoting inflammation, mast cells also have antiinflammatory functions. They release pro- as well as antiinflammatory mediators, depending on the biological setting. Here we aimed to better
Externí odkaz:
https://doaj.org/article/7e735f31a36b485bbd14ab87216dc27f
Publikováno v:
Food and Energy Security, Vol 9, Iss 3, Pp n/a-n/a (2020)
Abstract Anaerobic digestion (AD) currently relies heavily on crop feedstocks to maintain a constant output. A major annual crop used is Zea mays (maize), but this practice presents significant concerns because high energy inputs and food‐growing l
Externí odkaz:
https://doaj.org/article/bef85f95cb904de48fe21ac732e01423
Autor:
Jennifer Cohnen, Lisa Kornstädt, Lisa Hahnefeld, Nerea Ferreiros, Sandra Pierre, Ulrike Koehl, Thomas Deller, Gerd Geisslinger, Klaus Scholich
Publikováno v:
Cells, Vol 9, Iss 2, p 320 (2020)
Cancer-induced pain occurs frequently in patients when tumors or their metastases grow in the proximity of nerves. Although this cancer-induced pain states poses an important therapeutical problem, the underlying pathomechanisms are not understood. H
Externí odkaz:
https://doaj.org/article/b3af647564bf4020a84f3e882e2ed0a4
Autor:
Katharina Kern, Stephan M. G. Schäfer, Jennifer Cohnen, Sandra Pierre, Tabea Osthues, Neda Tarighi, Stefan Hohmann, Nerea Ferreiros, Bernhard Brüne, Andreas Weigert, Gerd Geisslinger, Marco Sisignano, Klaus Scholich
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophages are highly versatile cells, which acquire, depending on their microenvironment, pro- (M1-like), or antiinflammatory (M2-like) phenotypes. Here, we studied the role of the G-protein coupled receptor G2A (GPR132), in chemotactic migration a
Externí odkaz:
https://doaj.org/article/ab6fd2fa310846b9afe8da0fdd99b60a
Autor:
Lisa Maria Martin, Moritz Möller, Ulrike Weiss, Otto Quintus Russe, Klaus Scholich, Sandra Pierre, Gerd Geisslinger, Ellen Niederberger
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3255 (2019)
The stimulation of the AMP-activated kinase (AMPK) by 5-amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) has been associated with antihyperalgesia and the inhibition of nociceptive signaling in the spinal cord in models of paw inflammation.
Externí odkaz:
https://doaj.org/article/939df11695ca4a08867b7286a419a1a3
Autor:
Jason Kam, Swati Puranik, Rama Yadav, Hanna Manwaring, Sandra Pierre, Rakesh Srivastava, Rattan Yadav
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
Diabetes has become a highly problematic and increasingly prevalent disease world-wide. It has contributed towards 1.5 million deaths in 2012. Management techniques for diabetes prevention in high-risk as well as in affected individuals, beside medic
Externí odkaz:
https://doaj.org/article/e1914e4f474e4172b5c32e9be3f33f5d