Intestinal absorption of sphingosine: new insights on generated ceramide species using stable isotope tracing in vitro

Autor: Catherine Calzada, David Cheillan, Nina Ritsch, Cécile Vors, Annie Durand, Sandra Pesenti, Magali Pettazzoni, Emmanuelle Meugnier, Marie-Caroline Michalski, Armelle Penhoat

Publikováno v: Journal of Lipid Research, Vol 65, Iss 6, Pp 100557- (2024)

Abstract: Dietary sphingomyelin (SM) has been reported to favorably modulate postprandial lipemia. Mechanisms underlying these beneficial effects on cardiovascular risk markers are not fully elucidated. Rodent studies showed that tritiated SM was hyd

Externí odkaz: https://doaj.org/article/4e5e3792698d490e974da0aabf7c41ce

A low aromatic amino-acid diet improves renal function and prevent kidney fibrosis in mice with chronic kidney disease

Autor: Christophe Barba, Bérengère Benoit, Emilie Bres, Stéphanie Chanon, Aurélie Vieille-Marchiset, Claudie Pinteur, Sandra Pesenti, Griet Glorieux, Cécile Picard, Denis Fouque, Christophe O. Soulage, Laetitia Koppe

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract Despite decades of use of low protein diets (LPD) in the management of chronic kidney disease (CKD), their mechanisms of action are unclear. A reduced production of uremic toxins could contribute to the benefits of LPDs. Aromatic amino-acids

Externí odkaz: https://doaj.org/article/c3311138d3da4257aad3708803e12510

Milk polar lipids favorably alter circulating and intestinal ceramide and sphingomyelin species in postmenopausal women

Autor: Mélanie Le Barz, Cécile Vors, Emmanuel Combe, Laurie Joumard-Cubizolles, Manon Lecomte, Florent Joffre, Michèle Trauchessec, Sandra Pesenti, Emmanuelle Loizon, Anne-Esther Breyton, Emmanuelle Meugnier, Karène Bertrand, Jocelyne Drai, Chloé Robert, Annie Durand, Charlotte Cuerq, Patrice Gaborit, Nadine Leconte, Annick Bernalier-Donadille, Eddy Cotte, Martine Laville, Stéphanie Lambert-Porcheron, Lemlih Ouchchane, Hubert Vidal, Corinne Malpuech-Brugère, David Cheillan, Marie-Caroline Michalski

Publikováno v: JCI Insight, Vol 6, Iss 10 (2021)

BACKGROUND High circulating levels of ceramides (Cer) and sphingomyelins (SM) are associated with cardiometabolic diseases. The consumption of whole fat dairy products, naturally containing such polar lipids (PL), is associated with health benefits,

Externí odkaz: https://doaj.org/article/8a658e9e68e94900b33710e1806223da

Obesity activates immunomodulating properties of mesenchymal stem cells in adipose tissue with differences between localizations

Autor: Camille Lefevre, Claudie Pinteur, Hubert Vidal, Anne Mey, Sandra Pesenti, Thomas Verdier, Stéphanie Chanon, Dimitri Chartoire, José Candido Ferraz, Aurélie Vieille-Marchiset, Laurent Genestier

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (6), ⟨10.1096/fj.202002046RR⟩

International audience; Mesenchymal stem cells from healthy adipose tissue are adipocytes progenitors with immunosuppressive potential that are used for years in cell therapy. Whether adipose stem cells (ASC) may prevent inflammation in early obesity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3b9bfba95427a1daf73e364d790cb
https://hal.inrae.fr/hal-03331272

Human mesenchymal stem cells improve rat islet functionality under cytokine stress with combined upregulation of heme oxygenase-1 and ferritin

Autor: Sandrine Lablanche, Cécile Cottet-Rousselle, Justine Cristante, Sandra Pesenti, Eric Fontaine, Frédéric Lamarche, Emily Tubbs, Anne-Sophie Gauchez, Anaïck Moisan, Jean-Marc Moulis, Pierre-Yves Benhamou, Camille Laporte, Catherine Garrel

Publikováno v: Stem Cell Research & Therapy
Stem Cell Research and Therapy
Stem Cell Research and Therapy, BioMed Central, 2019, 10 (1), pp.1-12. ⟨10.1186/s13287-019-1190-4⟩
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2019)
Stem Cell Research and Therapy (10), 1-12. (2019)

Background Islets of Langerhans transplantation is a promising therapy for type 1 diabetes mellitus, but this technique is compromised by transplantation stresses including inflammation. In other tissues, co-transplantation with mesenchymal stem cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1707c93b6a98a6d5cb66c1147d1e62b7
https://doi.org/10.1186/s13287-019-1190-4