Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sandra Palus"'
Autor:
Luping Yuan, Jochen Springer, Sandra Palus, Silvia Busquets, Queralt Jové, Edson Alves de Lima Junior, Markus S. Anker, Stephan vonHaehling, Natalia Álvarez Ladrón, Oliver Millman, Annemijn Oosterlee, Agata Szymczyk, Francisco Javier López‐Soriano, Stefan D. Anker, Andrew J.S. Coats, Josep M. Argiles
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 653-660 (2023)
Abstract Background Beta‐blockers and selected stereoisomers of beta‐blockers, like bisoprolol and S‐pindolol (ACM‐001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of o
Externí odkaz:
https://doaj.org/article/748d4538c7ce45089201c07ab020fbb6
Autor:
Sandra Palus, Yulia Elkina, Tanja Braun, Stephan vonHaehling, Wolfram Döhner, Stefan D. Anker, Anthony Cerami, Michael Brines, Jochen Springer
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2202-2210 (2022)
Abstract Background Cancer cachexia (CC) is a severe complication during the last stages of the disease, which is characterized by the substantial loss of muscle and fat mass. Currently, there is no effective treatment of CC. Erythropoietin plays tis
Externí odkaz:
https://doaj.org/article/7cecc6d28b3f45f4919338edfc4de23c
Autor:
Mareike S. Pötsch, Junichi Ishida, Sandra Palus, Anika Tschirner, Stephan vonHaehling, Wolfram Doehner, Stefan D. Anker, Jochen Springer
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 594-605 (2020)
Abstract Background Cachexia, a common manifestation of malignant cancer, is associated with wasting of skeletal muscle and fat tissue. In this study, we investigated the effects of a new first in class anabolic catabolic transforming agent on skelet
Externí odkaz:
https://doaj.org/article/d33c924446314452a3eb17c801bdd162
Publikováno v:
JCSM Rapid Communications, Vol 3, Iss 1, Pp 3-10 (2020)
Abstract Background Medroxyprogesterone and megestrol acetate are synthetic progesterone derivatives. Progestagen is an approved drug for cancer cachexia in the USA and in some European countries. These agents have been described to increase appetite
Externí odkaz:
https://doaj.org/article/48fec7999dbf4dc9a6b3bd8cfc1832fd
Autor:
Sandra Palus, Robert Schur, Yoshihiro J Akashi, Barbara Bockmeyer, Rakesh Datta, Heather Halem, Jesse Dong, Michael D Culler, Volker Adams, Stefan D Anker, Jochen Springer
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26865 (2011)
Cardiac cachexia is a serious complication of chronic heart failure with a prevalence of 10-16% and poor prognosis. There are no current therapy options for cardiac cachexia. Ghrelin is the natural ligand for the GHS-1a-receptor and a potential targe
Externí odkaz:
https://doaj.org/article/3c02157f338a43e69569cfa850ae7990
Autor:
Mareike S. Poetsch, Sandra Palus, Sophie Van Linthout, Stephan von Haehling, Wolfram Doehner, Andrew J.S. Coats, Stefan D. Anker, Jochen Springer
Publikováno v:
European Journal of Heart Failure.
Autor:
Luping Yuan, Jochen Springer, Sandra Palus, Silvia Busquets, Queralt Jové, Edson Alves de Lima Junior, Markus S. Anker, Stephan von Haehling, Natalia Álvarez Ladrón, Oliver Millman, Annemijn Oosterlee, Agata Szymczyk, Francisco Javier López‐Soriano, Stefan D. Anker, Andrew J.S. Coats, Josep M. Argiles
Publikováno v:
Journal of cachexia, sarcopenia and muscleReferences.
Beta-blockers and selected stereoisomers of beta-blockers, like bisoprolol and S-pindolol (ACM-001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of oxprenolol in two preclinical
Autor:
Stefan D. Anker, Anika Tschirner, Jochen Springer, Mareike S Pötsch, Wolfram Doehner, Stephan von Haehling, Sandra Palus, Junichi Ishida
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 594-605 (2020)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
BACKGROUND: Cachexia, a common manifestation of malignant cancer, is associated with wasting of skeletal muscle and fat tissue. In this study, we investigated the effects of a new first in class anabolic catabolic transforming agent on skeletal muscl
Autor:
Stephan von Haehling, Vincenzo Mollace, Francesca Bosco, Frederic Jaisser, Gerd Hasenfuss, Cristina Carresi, Miriam Scicchitano, Saverio Nucera, Jochen Springer, Celine Latouche, Federica Scarano, Vincenzo Musolino, Micaela Gliozzi, Sandra Palus, Stefan D. Anker
Publikováno v:
ESC Heart Failure. 6:89-97
AIMS Cachexia is a severe consequence of cancer. Although cancer-induced heart atrophy leads to cardiac dysfunction and heart failure (HF), biomarkers for their diagnosis have not been identified. Neutrophil gelatinase-associated lipocalin (NGAL) is
Autor:
Mauro Giacca, Gianluca Gortan Cappellari, Rocco Barazzoni, Michela Zanetti, Pierandrea Vinci, Nicole Ebner, Gianfranco Sinagra, Stephan von Haehling, A. Semolic, Sandra Palus, Jochen Springer, Giulia Ruozi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 8:991-998
Background Chronic heart failure (CHF) is associated with skeletal muscle abnormalities contributing to exercise intolerance, muscle loss, and negative impact on patient prognosis. A primary role has been proposed for mitochondrial dysfunction, which