Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sandra Pagano"'
Autor:
Sarah Figarol, Célia Delahaye, Rémi Gence, Aurélia Doussine, Juan Pablo Cerapio, Mathylda Brachais, Claudine Tardy, Nicolas Béry, Raghda Asslan, Jacques Colinge, Jean-Philippe Villemin, Antonio Maraver, Irene Ferrer, Luis Paz-Ares, Linda Kessler, Francis Burrows, Isabelle Lajoie-Mazenc, Vincent Dongay, Clara Morin, Amélie Florent, Sandra Pagano, Estelle Taranchon-Clermont, Anne Casanova, Anne Pradines, Julien Mazieres, Gilles Favre, Olivier Calvayrac
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Drug-tolerance has emerged as one of the major non-genetic adaptive processes driving resistance to targeted therapy (TT) in non-small cell lung cancer (NSCLC). However, the kinetics and sequence of molecular events governing this adaptive r
Externí odkaz:
https://doaj.org/article/5612bcd3b3224ee3a0571c7b20e6c3df
Farnesyltransferase inhibition overcomes the adaptive resistance to osimertinib in EGFR-mutant NSCLC
Autor:
Sarah Figarol, Célia Delahaye, Rémi Gence, Raghda Asslan, Sandra Pagano, Claudine Tardy, Jacques Colinge, Jean-Philippe Villemin, Antonio Maraver, Irene Ferrer, Luis Paz-Ares, Isabelle Lajoie-Mazenc, Estelle Clermont, Anne Casanova, Anne Pradines, Julien Mazières, Olivier Calvayrac, Gilles Favre
Drug-tolerant “dormant” cells (DTC) have emerged as one of the major non-genetic mechanisms driving resistance to targeted therapy in lung cancer, although the sequence of events leading to entry and exit from dormancy remain poorly described. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d21ecd0b9fc2e402d77e450cb2f897c
https://doi.org/10.1101/2022.04.01.486707
https://doi.org/10.1101/2022.04.01.486707
Publikováno v:
Cancer Research. 82:656-656
Purpose: Drug-tolerance has emerged as one of the major non-genetic mechanism that drives resistance to targeted therapies in lung cancers. Identification of drug-tolerant cells (DTC) vulnerabilities thus represents an attractive strategy to prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a3ba4bad9e05618b2efb98ad667c17
https://doi.org/10.1158/1538-7445.am2022-656
https://doi.org/10.1158/1538-7445.am2022-656