Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Sandra P, Tou"'
1
Assessment of PDK4 and TTN gene variants in 48 Doberman Pinschers with dilated cardiomyopathy
Autor: Sandra P. Tou, Kathryn M. Meurs, Theresa C. De Francesco, Darcy B. Adin, Bruce W. Keene, Joshua A. Stern
Publikováno v: Journal of the American Veterinary Medical Association. 257:1041-1044
OBJECTIVE To evaluate the frequency of variants in the pyruvate kinase dehydrogenase 4 (PDK4) and titin (TTN) genes in a group of Doberman Pinschers with dilated cardiomyopathy (DCM) and to determine whether there were unique clinical attributes to e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3f5cd4bed902811a4ed4562ae010faa
https://doi.org/10.2460/javma.2020.257.10.1041
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2
Retrospective evaluation of the safety and tolerability of pimobendan in cats with obstructive vs nonobstructive cardiomyopathy
Autor: Efrem Z Kussin, Teresa C. DeFrancesco, Sandra P. Tou, Melissa A. Tropf, Jessica L. Ward, Bruce W. Keene
Publikováno v: Journal of Veterinary Internal Medicine
Background Pimobendan is frequently used off‐label for treatments of cats with congestive heart failure (CHF). Concern exists regarding the safety of pimobendan in cats with outflow tract obstruction (OTO). Objectives In cats treated with pimobenda
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3aa56997e4f907449b1c7ddf670c10d
https://doi.org/10.1111/jvim.15920
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3
Renin‐angiotensin aldosterone profile before and after angiotensin‐converting enzyme‐inhibitor administration in dogs with angiotensin‐converting enzyme gene polymorphism
Autor: Teresa C. DeFrancesco, Sandra P. Tou, Darcy B. Adin, Oliver Domenig, Joshua A. Stern, Kathryn M. Meurs, Clarke E. Atkins, Bruce W. Keene
Publikováno v: Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 600-606 (2020)
Background An angiotensin‐converting enzyme (ACE) gene polymorphism occurs in dogs; however, functional importance is not well studied. Hypothesis We hypothesized that dogs with the polymorphism would show alternative renin‐angiotensin aldosteron
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a80452e3c09034591e71438a19d23c5
http://europepmc.org/articles/PMC7097578
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4
Myxomatous mitral valve disease in Miniature Schnauzers and Yorkshire Terriers: 134 cases (2007-2016)
Autor: Kerry A O'Donnell, Darcy B. Adin, Dylan DeProspero, Clarke E. Atkins, Teresa C. DeFrancesco, Kathryn M. Meurs, Bruce W. Keene, Sandra P. Tou
Publikováno v: Journal of the American Veterinary Medical Association. 259(12)
OBJECTIVE To characterize features of myxomatous mitral valve disease (MMVD) in Miniature Schnauzers and Yorkshire Terriers. ANIMALS 69 Miniature Schnauzers and 65 Yorkshire Terriers, each with MMVD. PROCEDURES Medical record data for each dog were c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca54a5b9d741c9f2dd54b35ffbafa853
https://pubmed.ncbi.nlm.nih.gov/34757932
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5
A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death
Autor: Sandra P. Tou, G. Diane Shelton, Teresa C. DeFrancesco, Oriana Yost, Natasha J. Olby, Bruce W. Keene, Sunshine Lahmers, Kathleen Woodruff, Chandra Saripalli, Justin Kolb, Henk Granzier, Paola Tonino, Kathryn M. Meurs, Darcy B. Adin, Steven G. Friedenberg
Publikováno v: Human Genetics. 138:515-524
The dog provides a large animal model of familial dilated cardiomyopathy for the study of important aspects of this common familial cardiovascular disease. We have previously demonstrated a form of canine dilated cardiomyopathy in the Doberman pinsch
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ab439d781e5add4e6fdcf63e1f8cb9
https://doi.org/10.1007/s00439-019-01973-2
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6
Echocardiographic phenotype of canine dilated cardiomyopathy differs based on diet type
Autor: Teresa C. DeFrancesco, Clarke E. Atkins, Sandra P. Tou, Darcy B. Adin, Bruce W. Keene, Kathryn M. Meurs, Lara Barron, Brent Aona, Korinn E. Saker, Kari Kurtz
Publikováno v: Journal of Veterinary Cardiology. 21:1-9
Introduction Canine dilated cardiomyopathy (DCM) can result from numerous etiologies including genetic mutations, infections, toxins, and nutritional imbalances. This study sought to characterize differences in echocardiographic findings between dogs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492d0fd8c5615fd6152f49863106753c
https://doi.org/10.1016/j.jvc.2018.11.002
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7
Myxomatous mitral valve disease in the miniature poodle: A retrospective study
Autor: Clarke E. Atkins, Teresa C. DeFrancesco, Kathryn M. Meurs, Bruce W. Keene, K. O’Donnell, Darcy B. Adin, Sandra P. Tou
Publikováno v: The Veterinary Journal. 244:94-97
Myxomatous mitral valve disease (MMVD) is the most common cardiovascular disease in the dog. The natural history of the disease is wide ranging and includes patients without clinical signs as well as those with significant clinical consequences from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fea68406463466bc607ec000d7596dc
https://doi.org/10.1016/j.tvjl.2018.12.019
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8
A deleterious mutation in the ALMS1 gene in a naturally occurring model of hypertrophic cardiomyopathy in the Sphynx cat
Autor: Kathryn M. Meurs, Darcy B. Adin, Dylan DeProspero, J. Ashley Ezzell, David E. Malarkey, Steven G. Friedenberg, Brian G. Williams, Bruce W. Keene, Sandra P. Tou, Teresa C. DeFrancesco
Publikováno v: Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-7 (2021)
Background Familial hypertrophic cardiomyopathy is a common inherited cardiovascular disorder in people. Many causal mutations have been identified, but about 40% of cases do not have a known causative mutation. Mutations in the ALMS1 gene are associ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8495bdc98da89cebe71eec250f3f1e77
http://europepmc.org/articles/PMC7913409
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9
Assessment of
Autor: Kathryn M, Meurs, Joshua A, Stern, Darcy, Adin, Bruce W, Keene, Theresa C, De Francesco, Sandra P, Tou
Publikováno v: Journal of the American Veterinary Medical Association. 257(10)
To evaluate the frequency of variants in the pyruvate kinase dehydrogenase 4 (48 Doberman Pinschers with DCM.Doberman Pinschers with recently diagnosed DCM were identified, and genomic DNA from each was genotyped with a PCR assay for detection ofOf t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::784764a0fb84c282ea12b420eea76580
https://pubmed.ncbi.nlm.nih.gov/33135971
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10
Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure
Autor: Lara Barron, John D. Bonagura, Brent Aona, Darcy B. Adin, Bruce W. Keene, Anna McManamey, Ashley L. Walker, Kathryn M. Meurs, Kari Kurtz, James B Robertson, Sandra P. Tou, Teresa C. DeFrancesco
Publikováno v: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology. 40
Introduction Dilated cardiomyopathy (DCM) in dogs has been associated with feeding of grain-free (GF), legume-rich diets. Some dogs with presumed diet-associated DCM have shown improved myocardial function and clinical outcomes following a change in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93925cedc1e38ea68c0e96614cf2ee
https://pubmed.ncbi.nlm.nih.gov/33741312
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