Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sandra Nestler"'
Autor:
Max Schlueter, Sandra Nestler-Parr
Publikováno v:
Journal of Comparative Effectiveness Research, Vol 13, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/506d171435494f9a9ed32d01619d72b3
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Hereditary transthyretin amyloidosis (ATTRv) is an ultra-rare, life-shortening disease with a high unmet need. This study examined ATTRv caregiver health-related quality of life (HRQoL) and productivity. Methods A cross-sectional
Externí odkaz:
https://doaj.org/article/163cde2fb9ee48dba2f2808e8ac023c7
Autor:
Claudia Merger, Alexandre René, Kirsten Fischer, Peter Bouss, Sandra Nestler, David Dahmen, Carsten Honerkamp, Moritz Helias
Publikováno v:
Physical Review X, Vol 13, Iss 4, p 041033 (2023)
One challenge of physics is to explain how collective properties arise from microscopic interactions. Indeed, interactions form the building blocks of almost all physical theories and are described by polynomial terms in the action. The traditional a
Externí odkaz:
https://doaj.org/article/a523f110422843ccba803710d4613280
Publikováno v:
Physical Review Research, Vol 5, Iss 3, p 033177 (2023)
Neuronal systems need to process temporal signals. Here, we show how higher-order temporal (co)fluctuations can be employed to represent and process information. Concretely, we demonstrate that a simple biologically inspired feedforward neuronal mode
Externí odkaz:
https://doaj.org/article/ab662ab4e8944795b5f003cb99af225a
Publikováno v:
Advances in continuous and discrete models 2022(1), 13 (2022). doi:10.1186/s13662-022-03686-9
Advances in continuous and discrete models 2022(1), 13 (2022). doi:10.1186/s13662-022-03686-9
Published by BioMed Central, London
Published by BioMed Central, London
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdf8173d4ac623bed300d9df83295de
https://juser.fz-juelich.de/record/906138
https://juser.fz-juelich.de/record/906138
Autor:
Mondher Toumi, Zoltán Kaló, Elizabeth Molsen, Sandra Nestler-Parr, Christopher M. Blanchette, William K. Redekop, Thomas Morel, Steven Simoens, CL Pashos, D Korchagina, Ruediger Gatermann
Publikováno v:
Value in Health, 21(5), 493-500. Elsevier Ltd.
Background Successful development of new treatments for rare diseases (RDs) and their sustainable patient access require overcoming a series of challenges related to research and health technology assessment (HTA). These impediments, which may be uni
Autor:
Sandra Nestler-Parr, Katy L. Benjamin, Eleanor M. Perfetto, Margaret K. Vernon, Laurie B. Burke, Donald L. Patrick
Publikováno v:
Value in Health. 20:838-855
Background Rare diseases (RDs) affect a small number of people within a population. About 5000 to 8000 distinct RDs have been identified, with an estimated 6% to 8% of people worldwide suffering from an RD. Approximately 75% of RDs affect children. F
Autor:
Theresa Tesoro, Sandra Nestler-Parr, Zeba M. Khan, Dyfrig A. Hughes, Robert Babela, Trevor Richter, Elizabeth Molsen
Publikováno v:
Value in Health. 18(6):906-914
Background At present, there is no universal definition of rare disease. Objective To provide an overview of rare disease definitions currently used globally. Methods We systematically searched for definitions related to rare disease from organizatio
Publikováno v:
Food Additives & Contaminants. 22:58-64
The potency of ochratoxin A (OTA) as a renal carcinogen in the rat in response to lifetime administration by oral gavage is a basis of current concern about possible human risk from dietary exposure to the mycotoxin. In this study, dietary delivery o
Autor:
Christophe Cavin, Clotilde Verguet, Peter G. Mantle, Sandra Nestler, Benoît Schilter, Maricel Marin-Kuan, Dominique Piguet, Claudine Bezençon, Thierry Delatour
Publikováno v:
Toxicology and applied pharmacology. 224(2)
Kidney samples of male Fischer 344 (F-344) rats fed a carcinogenic dose of OTA over 7 days, 21 days and 12 months were analysed for various cell signalling proteins known to be potentially involved in chemical carcinogenicity. OTA was found to increa