Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sandra Montes Olivas"'
Autor:
Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander G Fletcher, Ann C Williams, Lucia Marucci, Martin Homer
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011386 (2023)
Organoids offer a powerful model to study cellular self-organisation, the growth of specific tissue morphologies in-vitro, and to assess potential medical therapies. However, the intrinsic mechanisms of these systems are not entirely understood yet,
Externí odkaz:
https://doaj.org/article/bc64428b884d4479a8b56223f15161f1
Autor:
Sandra Montes-Olivas, Yaz Ozten, Martin Homer, Katy Turner, Christopher K. Fairley, Jane S. Hocking, Desiree Tse, Nicolas Verschueren van Rees, William C. W. Wong, Jason J. Ong
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
ObjectivesTo illustrate the epidemiologic and cost-effectiveness impact of shifting the focus from population-based screening toward a targeted management approach for genital chlamydia infection.DesignModeling study, implementing an individual-based
Externí odkaz:
https://doaj.org/article/04ffbb4d151b46f4b6f73c4d83c468c2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 230-240 (2020)
Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell proliferation and differentiat
Externí odkaz:
https://doaj.org/article/9b85863fdf8041979dcae5f67fbcaf5c
Autor:
Elisa Pedone, Lorena Postiglione, Francesco Aulicino, Dan L. Rocca, Sandra Montes-Olivas, Mahmoud Khazim, Diego di Bernardo, Maria Pia Cosma, Lucia Marucci
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Cellular systems have numerous mechanisms to control gene expression. Here the authors build a Tet-On system with conditional destablising elements to regulate gene expression and protein stability, allowing fine modulation of mESC signalling pathway
Externí odkaz:
https://doaj.org/article/e79a3cc6f3294f59896d1257115ecf15
Autor:
Thomas E. Gorochowski, Sabine Hauert, Jan-Ulrich Kreft, Lucia Marucci, Namid R. Stillman, T.-Y. Dora Tang, Lucia Bandiera, Vittorio Bartoli, Daniel O. R. Dixon, Alex J. H. Fedorec, Harold Fellermann, Alexander G. Fletcher, Tim Foster, Luca Giuggioli, Antoni Matyjaszkiewicz, Scott McCormick, Sandra Montes Olivas, Jonathan Naylor, Ana Rubio Denniss, Daniel Ward
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Many complex behaviors in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are of great interest to bioengineer
Externí odkaz:
https://doaj.org/article/1690bd498c644b809310d629489f45c1
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Organoids are engineered three-dimensional tissue cultures derived from stem cells and capable of self-renewal and self-organization into a variety of progenitors and differentiated cell types. An organoid resembles the cellular structure of an organ
Externí odkaz:
https://doaj.org/article/814398dd1426400e925be7de922b8673
Autor:
Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander G. Fletcher, Ann C. Williams, Lucia Marucci, Martin Homer
Organoids offer a powerful model to study cellular self-organisation, the growth of specific tissue morphologiesin-vitro, and to assess potential medical therapies. However, the intrinsic mechanisms of these systems are not entirely understood yet, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c2465167792f8490c255d96ffdd069
https://doi.org/10.1101/2022.12.08.519603
https://doi.org/10.1101/2022.12.08.519603
Autor:
Antoni Matyjaszkiewicz, Tim Foster, Sabine Hauert, Jan-Ulrich Kreft, Jonathan Naylor, Daniel O. R. Dixon, T-Y Dora Tang, Thomas E. Gorochowski, Vittorio Bartoli, Luca Giuggioli, Daniel Ward, Ana Rubio Denniss, Harold Fellermann, Scott McCormick, Alex J. H. Fedorec, Lucia Marucci, Sandra Montes Olivas, Lucia Bandiera, Namid R. Stillman, Alexander G. Fletcher
Many complex behaviours in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are of great interest to bioenginee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cf728553d54cbdf8bc77238416303d
https://doi.org/10.20944/preprints202005.0058.v1
https://doi.org/10.20944/preprints202005.0058.v1
Autor:
Lucia Marucci, Daniel L. Rocca, Lorena Postiglione, Sandra Montes-Olivas, Francesco Aulicino, Maria Pia Cosma, Mahmoud Khazim, Elisa Pedone, Diego di Bernardo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Pedone, E, Postiglione, L, Aulicino, F, Rocca, D L, Montes-Olivas, S, Khazim, M, di Bernardo, D, Pia Cosma, M & Marucci, L 2019, ' A tunable dual-input system for on-demand dynamic gene expression regulation ', Nature Communications, vol. 10, 4481 (2019) . https://doi.org/10.1038/s41467-019-12329-9
Nature Communications
Pedone, E, Postiglione, L, Aulicino, F, Rocca, D L, Montes-Olivas, S, Khazim, M, di Bernardo, D, Pia Cosma, M & Marucci, L 2019, ' A tunable dual-input system for on-demand dynamic gene expression regulation ', Nature Communications, vol. 10, 4481 (2019) . https://doi.org/10.1038/s41467-019-12329-9
Cellular systems have evolved numerous mechanisms to adapt to environmental stimuli, underpinned by dynamic patterns of gene expression. In addition to gene transcription regulation, modulation of protein levels, dynamics and localization are essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e732dacf5438afe42ff6dd4489aac026
https://doi.org/10.1038/s41467-019-12329-9
https://doi.org/10.1038/s41467-019-12329-9
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 230-240 (2020)
Ward, D, Montes Olivas, S, Fletcher, A, Homer, M & Marucci, L 2020, ' Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts : Insights from an agent-based model ', Computational and Structural Biotechnology Journal, vol. 18, pp. 230-240 . https://doi.org/10.1016/j.csbj.2019.12.015
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 230-240 (2020)
Ward, D, Montes Olivas, S, Fletcher, A, Homer, M & Marucci, L 2020, ' Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts : Insights from an agent-based model ', Computational and Structural Biotechnology Journal, vol. 18, pp. 230-240 . https://doi.org/10.1016/j.csbj.2019.12.015
Graphical abstract
Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell prolif
Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4206fc939bb199fcd86d5bbd8058f769
https://pubmed.ncbi.nlm.nih.gov/33489001
https://pubmed.ncbi.nlm.nih.gov/33489001