Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sandra Milasta"'
Autor:
Mika B. Jekabsons, Mollie Merrell, Anna G. Skubiz, Noah Thornton, Sandra Milasta, Douglas Green, Taosheng Chen, Yan-Hong Wang, Bharathi Avula, Ikhlas A. Khan, Yu-Dong Zhou
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-24 (2023)
Abstract Gene expression signatures associated with breast cancer metastases suggest that metabolic re-wiring is important for metastatic growth in lungs, bones, and other organs. However, since pathway fluxes depend on additional factors such as ATP
Externí odkaz:
https://doaj.org/article/7e752c0384814035bfa0d6530ec190eb
Autor:
Heather S. Smallwood, Susu Duan, Marie Morfouace, Svetlana Rezinciuc, Barry L. Shulkin, Anang Shelat, Erika E. Zink, Sandra Milasta, Resha Bajracharya, Ajayi J. Oluwaseum, Martine F. Roussel, Douglas R. Green, Ljiljana Pasa-Tolic, Paul G. Thomas
Publikováno v:
Cell Reports, Vol 19, Iss 8, Pp 1640-1653 (2017)
Influenza is a worldwide health and financial burden posing a significant risk to the immune-compromised, obese, diabetic, elderly, and pediatric populations. We identified increases in glucose metabolism in the lungs of pediatric patients infected w
Externí odkaz:
https://doaj.org/article/14d7ac117c7942c4a3b2b1bd69d18796
Autor:
Stephen W.G. Tait, Andrew Oberst, Giovanni Quarato, Sandra Milasta, Martina Haller, Ruoning Wang, Maria Karvela, Gabriel Ichim, Nader Yatim, Matthew L. Albert, Grahame Kidd, Randall Wakefield, Sharon Frase, Stefan Krautwald, Andreas Linkermann, Douglas R. Green
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 878-885 (2013)
Programmed necrosis (or necroptosis) is a form of cell death triggered by the activation of receptor interacting protein kinase-3 (RIPK3). Several reports have implicated mitochondria and mitochondrial reactive oxygen species (ROS) generation as effe
Externí odkaz:
https://doaj.org/article/3bac1bef9e604f5e88b84218c1ad4f99
Autor:
Ricardo Weinlich, Andrew Oberst, Christopher P. Dillon, Laura J. Janke, Sandra Milasta, John R. Lukens, Diego A. Rodriguez, Prajwal Gurung, Chandra Savage, Thirumala D. Kanneganti, Douglas R. Green
Publikováno v:
Cell Reports, Vol 5, Iss 2, Pp 340-348 (2013)
Caspase-8 or cellular FLICE-like inhibitor protein (cFLIP) deficiency leads to embryonic lethality in mice due to defects in endothelial tissues. Caspase-8−/− and receptor-interacting protein kinase-3 (RIPK3)−/−, but not cFLIP−/− and RIPK
Externí odkaz:
https://doaj.org/article/ab6fdc9635da46a3b9b445a0ce2bf653
Autor:
Andrew M. Davidoff, Taosheng Chen, R. Kiplin Guy, Stephen White, Douglas R. Green, Junmin Peng, Chunxu Qu, Yong Cheng, Ashutosh Mishra, Jie J. Zheng, Zhenmei Li, Yinan Wu, Anang Shelat, Sourav Das, Brandon Young, Vincent A. Boyd, Su Sien Ong, Yingdi Wang, Ruoning Wang, Amit C. Nathwani, Pollyanna Goh, Ju Bao, Wenwei Lin, Jonathan Low, Jesse Davidson, Junfang Zhou, Rodrigo B. Interiano, Alaa M. AlTahan, Dongli Hu, Sandra Milasta, Jun Yang
Histone lysine demethylases facilitate the activity of oncogenic transcription factors, including possibly MYC. Here we show that multiple histone demethylases influence the viability and poor prognosis of neuroblastoma cells, where MYC is often over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e96065cdcf2a58b228dbe3422f2dd09
https://doi.org/10.1158/0008-5472.c.6508916
https://doi.org/10.1158/0008-5472.c.6508916
Autor:
Andrew M. Davidoff, Taosheng Chen, R. Kiplin Guy, Stephen White, Douglas R. Green, Junmin Peng, Chunxu Qu, Yong Cheng, Ashutosh Mishra, Jie J. Zheng, Zhenmei Li, Yinan Wu, Anang Shelat, Sourav Das, Brandon Young, Vincent A. Boyd, Su Sien Ong, Yingdi Wang, Ruoning Wang, Amit C. Nathwani, Pollyanna Goh, Ju Bao, Wenwei Lin, Jonathan Low, Jesse Davidson, Junfang Zhou, Rodrigo B. Interiano, Alaa M. AlTahan, Dongli Hu, Sandra Milasta, Jun Yang
Figure S1 shows siRNA screening in neuroblastoma cells. Figure S2 shows the dentification of ciclopirox that targets KDM4B. Figure S3 shows the CPX effect on other histone methyl marks. Figure S4 shows that CPX targets the Myc pathway. Figure S5 show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c093311ea8c98a81adeb8b227cbaf3d
https://doi.org/10.1158/0008-5472.22414205
https://doi.org/10.1158/0008-5472.22414205
Autor:
Marie Morfouace, Anang A. Shelat, Martine F. Roussel, Barry L. Shulkin, Resha Bajracharya, Heather S. Smallwood, Ljiljana Paša-Tolić, Sandra Milasta, Erika E. Zink, Ajayi J. Oluwaseum, Paul G. Thomas, Svetlana Rezinciuc, Susu Duan, Douglas R. Green
Publikováno v:
Cell Reports, Vol 19, Iss 8, Pp 1640-1653 (2017)
Influenza is a worldwide health and financial burden posing a significant risk to the immune-compromised, obese, diabetic, elderly, and pediatric populations. We identified increases in glucose metabolism in the lungs of pediatric patients infected w
Autor:
John D. Schuetz, Jie Zheng, Ju Bao, Hongbo Chi, John Lynch, Yao Wang, Partha Krishnamurthy, Amanda Nourse, Geoffrey Neale, Yu Fukuda, Andras Herras, Douglas R. Green, Juwina Wijaya, Sandra Milasta, Satish Cheepala
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Seminars in Immunology. 28:525-534
T cell activation results in a rapidly proliferating T cell endowed with a metabolic phenotype necessary for growth and division. However, before the cell can proceed towards this burst of cell division a phase of quiescence occurs, during which the
Autor:
Swantje Liedmann, Ruoning Wang, Cliff Guy, Katherine Verbist, Douglas R. Green, Marcin Kamiński, Sandra Milasta
Publikováno v:
Nature
Asymmetric cell division, the partitioning of cellular components in response to polarizing cues during mitosis, has roles in differentiation and development. It is important for the self-renewal of fertilized zygotes in Caenorhabditis elegans and ne