Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms

Autor: Patricia Ferrer, Andrea A. Berry, Allison N. Bucsan, Surendra K. Prajapati, Karthik Krishnan, Michelle C. Barbeau, David M. Rickert, Sandra Mendoza Guerrero, Miho Usui, Yonas Abebe, Asha Patil, Sumana Chakravarty, Peter F. Billingsley, Faith Pa’ahana-Brown, Kathy Strauss, Biraj Shrestha, Effie Nomicos, Gregory A. Deye, B. Kim Lee Sim, Stephen L. Hoffman, Kim C. Williamson, Kirsten E. Lyke

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract Resistance to clinical malaria takes years to develop even in hyperendemic regions and sterilizing immunity has rarely been observed. To evaluate the maturation of the host response against controlled repeat exposures to P. falciparum (Pf) N

Externí odkaz: https://doaj.org/article/7a3ddfce59954bb4905f2bfc862aaeeb

Safety and immunogenicity of a variant-adapted SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant as a booster in adults primed with authorized vaccines: a phase 3, parallel-group studyResearch in context

Autor: Guy de Bruyn, Joyce Wang, Annie Purvis, Martin Sanchez Ruiz, Haritha Adhikarla, Saad Alvi, Matthew I. Bonaparte, Daniel Brune, Agustin Bueso, Richard M. Canter, Maria Angeles Ceregido, Sachin Deshmukh, David Diemert, Adam Finn, Remi Forrat, Bo Fu, Julie Gallais, Paul Griffin, Marie-Helene Grillet, Owen Haney, Jeffrey A. Henderson, Marguerite Koutsoukos, Odile Launay, Federico Martinon Torres, Roger Masotti, Nelson L. Michael, Juliana Park, Doris Maribel Rivera-Medina, Natalya Romanyak, Chris Rook, Lode Schuerman, Lawrence D. Sher, Fernanda Tavares-Da-Silva, Ashley Whittington, Roman M. Chicz, Sanjay Gurunathan, Stephen Savarino, Saranya Sridhar, Allaw Mohammed, Babin Valérie, Babyak Jennifer, Ines Ben-Ghezala, Thomas Breuer, Corinne Breymeier, Anne Conrad, Ciarrah Holmqvist, Cristiana Costa-Araujo, Florence Coux, Christine Dellanno, Bertrand Dussol, Brandon Essink, Jesús Garrido, Pierre-Olivier Girodet, Claudia Gonzalez, Marie-Ange Grosbois, Justin Hammond, Chelsea He, Ciarrah Homlqvist, Kathy Hudzina, Mark Hutchens, Peta-Gay Jackson Booth, Arnel Joaquin, Rama Kandasamy, Jennifer Kasztejna, Michael Keefer, Murray Kimmel, Matthew Kresge, Fabrice Laine, Maeva Lefebvre, Denise Lopez, Malaborbor Perpetua Lourdes, Zoha Maakaroun-Vermesse, Caitlin Malishchak, Lisa Menard, Sandra Mendoza, Patrick Moore, Mounika Mulamalla, Patrick Mulholland, Jean-Francois Nicolas, Onyema Ogbuagu, Juan Ortiz, Ana Paula Perroud, Gina Peyton, Ya-Fen Purvis, Vanessa Raabe, Enrique Rivas, Nadine Rouphael, Beatrice Roy, Lola Sagot, Nessryne Sater, Howard Schwartz, Randall Severance, Jiayuan Shi, Magdalena Sobieszczyk, Charlene Stevens, Tran Phuong Thuy, Ramy Toma, Tina Tong, Sophie Tourneux, John Treanor, Núria Turet, Rachel Froget, Stephen Walsh, Judith White, Victor del Campo Perez, Lina Perez Breva, Pablo Rojo Conejo, Maria Belen Ruiz Antoraz, Toong Chin, Charlotte Fribbens, Adrian Phillipson, Rachel Kaminski, Stevan Emmett, Corey Hebert, Thomas Birch, Russell Roberson, Jeffrey Zacher, Sophie Gelu-Maury, Loron Loryne, Yvonne Davis

Publikováno v: EClinicalMedicine, Vol 62, Iss , Pp 102109- (2023)

Summary: Background: In a parallel-group, international, phase 3 study (ClinicalTrials.gov NCT04762680), we evaluated prototype (D614) and Beta (B.1.351) variant recombinant spike protein booster vaccines with AS03-adjuvant (CoV2 preS dTM-AS03). Meth

Externí odkaz: https://doaj.org/article/1e007f68a3a6477da53dae2f0eb41b2d

Coral affected by stony coral tissue loss disease can produce viable offspring

Autor: Sandra Mendoza Quiroz, Raúl Tecalco Renteria, Gandhi Germán Ramírez Tapia, Margaret W. Miller, Maria Victoria Grosso-Becerra, Anastazia T. Banaszak

Publikováno v: PeerJ, Vol 11, p e15519 (2023)

Stony coral tissue loss disease (SCTLD) has caused high mortality of at least 25 coral species across the Caribbean, with Pseudodiploria strigosa being the second most affected species in the Mexican Caribbean. The resulting decreased abundance and c

Externí odkaz: https://doaj.org/article/51401fec0fe141328622db3d550c1f92

Gold nanoparticles: synthesis, application in colon cancer therapy and new approaches - review

Autor: Karen Magaly Soto, Sandra Mendoza, Jose M. López-Romero, Jose Ramón Gasca-Tirado, Alejandro Manzano-Ramírez

Publikováno v: Green Chemistry Letters and Reviews, Vol 14, Iss 4, Pp 665-678 (2021)

Gold nanoparticles (AuNPs) are essential metal nanoparticles, and they have much application in different areas such as bio-imaging, medical therapy, enzyme assays and the environment. Various physical and chemical methods have been used for the synt

Externí odkaz: https://doaj.org/article/94275ad98a784dd796cdbd5eef94a575

Seizure or child abuse?

Autor: Consuelo del Rocio Luna Muñoz, Martín Seminario-Aliaga, Sandra Mendoza-Cernaqué, Giuliana Reyes-Florian

Publikováno v: Revista de la Facultad de Medicina Humana, Vol 21, Iss 3, Pp 659-665 (2021)

More child abuse cases are reported in Peru every year; however, there is no official report that describes the actual incidence, especially of the most vulnerable population such as infants. Signs of physical abuse generally involve brain injury and

Externí odkaz: https://doaj.org/article/6d9270e55cb74b2ca14cf1a46f329ab0