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pro vyhledávání: '"Sandra Meissner"'
Autor:
John P. Welsh, Michael A. Rauscher, Thomas O. Linden, Sandra Meissner, Haiying Bao, Jennifer M. Pollard, InKwan Han
Publikováno v:
Engineering in Life Sciences. 16:133-142
Application of scale-down high-throughput screening has become integral for process development of antibody therapeutic products. In this work, methods are described for using high-throughput techniques to develop a multicolumn chromatography purific
Autor:
Sandra Meissner, Joseph Nti-Gyabaah, Janelle Konietzko, Edward Glowacki, David J. Roush, Rebecca A. Chmielowski, Thomas O. Linden
Publikováno v:
Biotechnology progress. 30(3)
Clearance of aggregates during protein purification is increasingly paramount as protein aggregates represent one of the major impurities in biopharmaceutical products. Aggregates, especially dimer species, represent a significant challenge for purif