Thrombo-tag, an in vivo formed nanotracer for the detection of thrombi in mice by fast pre-targeted molecular imaging

Autor: Fernando Herranz, Irene Fernández-Barahona, José M. Adrover, Andrés Hidalgo, Jesús Ruiz-Cabello, Juan Pellico, Sandra Martín-Salamanca

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Adrover, J M, Pellico, J, Fernández-barahona, I, Martín-salamanca, S, Ruiz-cabello, J, Hidalgo, A & Herranz, F 2020, ' Thrombo-tag, an in vivo formed nanotracer for the detection of thrombi in mice by fast pre-targeted molecular imaging ', Nanoscale, vol. 12, no. 45, pp. 22978-22987 . https://doi.org/10.1039/D0NR04538A

Radioisotope-labelled nanoparticles permit novel applications in molecular imaging, while recent developments in imaging have enabled direct visualization of biological processes. While this holds true for pathological processes that are stable in ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14422de3227b34dd5d72b9b89dcbdb4b
https://doi.org/10.1039/d0nr04538a

Thrombo-tag, an

Autor: José M, Adrover, Juan, Pellico, Irene, Fernández-Barahona, Sandra, Martín-Salamanca, Jesús, Ruiz-Cabello, Andrés, Hidalgo, Fernando, Herranz

Publikováno v: Nanoscale. 12(45)

Radioisotope-labelled nanoparticles permit novel applications in molecular imaging, while recent developments in imaging have enabled direct visualization of biological processes. While this holds true for pathological processes that are stable in ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fcb1ecb88dc3b1bf4a5972105f2335c1
https://pubmed.ncbi.nlm.nih.gov/33053000

Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges

Autor: Thomas Seidenbecher, Sandra Martín-Salamanca, Jan-Kolja Strecker, Xiaolin Li, Jens Minnerup, Arthur Liesz, Michael Heming, Christian Thomas, Sven G. Meuth, Maike Hartlehnert, Anna-Lena Börsch, I-Na Lu, Alessio Ricci, Andrés Hidalgo, David Schafflick, Mathias Pawlak, Jolien Wolbert, Heinz Wiendl, Gerd Meyer zu Hörste

Publikováno v: Nature neuroscience. 24(9)

The CNS is ensheathed by the meninges and cerebrospinal fluid, and recent findings suggest that these CNS-associated border tissues have complex immunological functions. Unlike myeloid lineage cells, lymphocytes in border compartments have yet to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dba00555667e2c9772d15c9a6330c09
https://pubmed.ncbi.nlm.nih.gov/34253922

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

Autor: Cristina López-Rodríguez, Shu Zhen Chong, Jaime García-Prieto, Carlos Silvestre-Roig, Monica Gomez-Parrizas, José M. Adrover, Juan A. Quintana, Jorge López, Francisco Abad-Santos, Ana Victoria Lechuga-Vieco, David Sancho, Maximilien Evrard, Christian Weber, María A. Moro, Linnea A. Weiss, Maria Casanova-Acebes, Lai Guan Ng, Alexander Zarbock, Itziar Cossío, Borja Ibanez, Carlos del Fresno, Françoise Bachelerie, Jan Rossaint, Hector Huerga-Encabo, Alejandra Aroca-Crevillen, Andrés Hidalgo, Sandra Martín-Salamanca, Cecilia Muñoz-Calleja, Georgiana Crainiciuc, Kiril Bidzhekov, Karl Balabanian, Oliver Soehnlein, María Isabel Cuartero, Iván Ballesteros

Publikováno v: Immunity, 50(2), 390-402. Cell Press
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Immunity
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Neutrophils eliminate pathogens efficiently but can inflict severe damage to the host if they over-activate within blood vessels. It is unclear how immunity solves the dilemma of mounting an efficient anti-microbial defense while preserving vascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1ce54b41a61ac7131fe5b451395fb7
https://doi.org/10.1016/j.immuni.2019.11.001