Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sandra Malmgren Hill"'
Autor:
Anna Maria Eisele-Bürger, Frederik Eisele, Sandra Malmgren Hill, Xinxin Hao, Kara L. Schneider, Rahmi Imamoglu, David Balchin, Beidong Liu, F. Ulrich Hartl, Peter V. Bozhkov, Thomas Nyström
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113372- (2023)
Summary: Metacaspases are ancestral homologs of caspases that can either promote cell death or confer cytoprotection. Furthermore, yeast (Saccharomyces cerevisiae) metacaspase Mca1 possesses dual biochemical activity: proteolytic activity causing cel
Externí odkaz:
https://doaj.org/article/9af3080157bc43d7b143e62b2b0ce9aa
Autor:
Sandra Malmgren Hill, Xinxin Hao, Johan Grönvall, Stephanie Spikings-Nordby, Per O. Widlund, Triana Amen, Anna Jörhov, Rebecca Josefson, Daniel Kaganovich, Beidong Liu, Thomas Nyström
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 826-838 (2016)
Age can be reset during mitosis in both yeast and stem cells to generate a young daughter cell from an aged and deteriorated one. This phenomenon requires asymmetry-generating genes (AGGs) that govern the asymmetrical inheritance of aggregated protei
Externí odkaz:
https://doaj.org/article/85711078b4514e339fb3c9bf5ed15b8d
Autor:
Sandra Malmgren Hill, Thomas Nyström
Publikováno v:
eLife, Vol 5 (2016)
A previously unknown pathway can selectively degrade mitochondrial proteins in aged and stressed cells without destroying the organelle itself.
Externí odkaz:
https://doaj.org/article/6c717d8d9084480094b2dd8eeac54381
Autor:
Per O. Widlund, Sandra Malmgren Hill, Katharina Keuenhof, Thomas Nyström, Kara L. Schneider, Johanna L. Höög, Lisa Larsson Berglund
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
When the temperature is increased, the heat-shock response is activated to protect the cellular environment. The transcriptomics and proteomics of this process are intensively studied, while information about how the cell responds structurally to hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e975848fd311fc66d2e517f70eaa804
http://europepmc.org/articles/PMC8403982
http://europepmc.org/articles/PMC8403982
Autor:
Sandra Malmgren Hill, Sung Min Son, David C. Rubinsztein, Farah H. Siddiqi, Hyunjeong Kim, Lidia Wrobel, Cansu Karabiyik
The mechanistic target of rapamycin complex 2 (mTORC2) controls cell metabolism and survival in response to environmental inputs. Dysregulation of mTORC2 signaling has been linked to diverse human diseases, including cancer and metabolic disorders, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8531bf5ae99e5e8a0a1d794883da1cd7
Autor:
Marco M. Manni, Lidia Wrobel, Sandra Malmgren Hill, Sung Min Son, Julien Villeneuve, So Jung Park, Claudia Puri, Motoki Fujimaki, Eleanna Stamatakou, Ye Zhu, David C. Rubinsztein, Marian Fernandez-Estevez, Farah H. Siddiqi
Publikováno v:
Cell Discovery
Cell Discovery, Vol 6, Iss 1, Pp 1-1 (2020)
Cell Discovery, Vol 6, Iss 1, Pp 1-1 (2020)
The lysosomal degradation pathway of macroautophagy (herein referred to as autophagy) plays a crucial role in cellular physiology by regulating the removal of unwanted cargoes such as protein aggregates and damaged organelles. Over the last five deca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc098e337e62de263c1df0cf529850a
https://pubmed.ncbi.nlm.nih.gov/32377374
https://pubmed.ncbi.nlm.nih.gov/32377374
Autor:
Sandra Malmgren Hill, Sung Min Son, Marco M. Manni, Motoki Fujimaki, Marian Fernandez-Estevez, Julien Villeneuve, Claudia Puri, So Jung Park, Farah H. Siddiqi, David C. Rubinsztein, Ye Zhu, Eleanna Stamatakou, Lidia Wrobel
Publikováno v:
Cell Discovery
Cell Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
The lysosomal degradation pathway of macroautophagy (herein referred to as autophagy) plays a crucial role in cellular physiology by regulating the removal of unwanted cargoes such as protein aggregates and damaged organelles. Over the last five deca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0090f0cb5b90dd191e846940f98ff4e
Publikováno v:
Autophagy. 17:1052-1053
VCP/p97 is an essential multifunctional protein implicated in a plethora of intracellular quality control systems, and abnormal function of VCP is the underlying cause of several neurodegenerative disorders. We reported that VCP regulates the levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c937019fdaf7d3a0a5a63486640574
https://doi.org/10.1080/15548627.2021.1898742
https://doi.org/10.1080/15548627.2021.1898742