Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sandra M. Sanabria-Bohórquez"'
Autor:
Sandra M. Sanabria Bohórquez, Suzanne Baker, Paul T. Manser, Matteo Tonietto, Christopher Galli, Kristin R. Wildsmith, Yixuan Zou, Geoffrey A. Kerchner, Robby Weimer, Edmond Teng
Publikováno v:
Frontiers in Neuroimaging, Vol 3 (2024)
PurposeWe evaluated the impact of partial volume correction (PVC) methods on the quantification of longitudinal [18F]GTP1 tau positron-emission tomography (PET) in Alzheimer's disease and the suitability of describing the tau pathology burden tempora
Externí odkaz:
https://doaj.org/article/935c608a68ca4a409b94bd58178354e4
Autor:
Andrés Cervantes, Josep Tabernero, José Baselga, Premal Patel, Yibing Yan, Kui Lin, Raymond D. Meng, Sandra M. Sanabria Bohórquez, Wai Y. Chan, Michelle Nannini, Jin Zhu, Nageshwar Budha, Luna Musib, Juan Manuel Sanchis-García, Rafael Morales-Barrera, José Alejandro Pérez-Fidalgo, Teresa Macarulla, Mafalda Oliveira, Susana Roselló, Desamparados Roda, Cristina Saura
Supplementary Table S1. IC50 values of ipatasertib on cell viability in cell lines with or without alterations in PTEN or PIK3CA. Supplementary Table S2. Percent tumor growth inhibition (%TGI) in xenograft models with or without alterations in PTEN o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e4701c0f95763c34a048939d9dd118
https://doi.org/10.1158/2159-8290.22531864
https://doi.org/10.1158/2159-8290.22531864
Autor:
Kristin R. Wildsmith, Randall J. Bateman, Paul T. Manser, Balazs Toth, Sandra M. Sanabria-Bohórquez, Nicolas R. Barthélemy, Michael Keeley, Edmond Teng, Robby M. Weimer
Publikováno v:
Journal of Alzheimer's Disease. 85:415-429
Background: Understanding patterns of association between CSF phosphorylated tau (p-tau) species and clinical disease severity will aid Alzheimer’s disease (AD) diagnosis and treatment. Objective: To evaluate changes in tau phosphorylation ratios t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a0bea7962fd4765cc9818dc811bda4
https://doi.org/10.3233/jad-210677
https://doi.org/10.3233/jad-210677
Autor:
Laura Kist de Ruijter, Pim P. van de Donk, Jahlisa S. Hooiveld-Noeken, Danique Giesen, Sjoerd G. Elias, Marjolijn N. Lub-de Hooge, Sjoukje F. Oosting, Mathilde Jalving, Wim Timens, Adrienne H. Brouwers, Thomas C. Kwee, Jourik A. Gietema, Rudolf S. N. Fehrmann, Bernard M. Fine, Sandra M. Sanabria Bohórquez, Mahesh Yadav, Hartmut Koeppen, Jing Jing, Sebastian Guelman, Mark T. Lin, Michael J. Mamounas, Jeffrey Ryan Eastham, Patrick K. Kimes, Simon P. Williams, Alexander Ungewickell, Derk J. A. de Groot, Elisabeth G. E. de Vries
Publikováno v:
Nature Medicine, 28. Nature Publishing Group
Immune checkpoint inhibitors (ICIs), by reinvigorating CD8+ T cell mediated immunity, have revolutionized cancer therapy. Yet, the systemic CD8+ T cell distribution, a potential biomarker of ICI response, remains poorly characterized. We assessed saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fad80f7e4b7ae3586f26895a3559fcd
https://research.rug.nl/en/publications/c56d04f1-2d9e-4214-836f-e0cf92446507
https://research.rug.nl/en/publications/c56d04f1-2d9e-4214-836f-e0cf92446507
Autor:
Susanne Ostrowitzki, Tobias Bittner, Kaycee M. Sink, Howard Mackey, Christina Rabe, Lawrence S. Honig, Emanuele Cassetta, Michael Woodward, Mercè Boada, Christopher H. van Dyck, Timo Grimmer, Dennis J. Selkoe, Andres Schneider, Kathleen Blondeau, Nan Hu, Angelica Quartino, David Clayton, Michael Dolton, Yifan Dang, Beth Ostaszewski, Sandra M. Sanabria-Bohórquez, Michael Rabbia, Balazs Toth, Udo Eichenlaub, Jillian Smith, Lee A. Honigberg, Rachelle S. Doody
Publikováno v:
JAMA neurology. 79(11)
ImportanceAlzheimer disease (AD), a neurodegenerative disease characterized by β-amyloid plaques and τ tangles in the brain, represents an unmet medical need with no fully approved therapeutics to modify disease progression.ObjectiveTo investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173bd06a5f646f9e109a57dd1b9fccff
https://pubmed.ncbi.nlm.nih.gov/36121669
https://pubmed.ncbi.nlm.nih.gov/36121669
Autor:
Laura, Kist de Ruijter, Pim P, van de Donk, Jahlisa S, Hooiveld-Noeken, Danique, Giesen, Sjoerd G, Elias, Marjolijn N, Lub-de Hooge, Sjoukje F, Oosting, Mathilde, Jalving, Wim, Timens, Adrienne H, Brouwers, Thomas C, Kwee, Jourik A, Gietema, Rudolf S N, Fehrmann, Bernard M, Fine, Sandra M, Sanabria Bohórquez, Mahesh, Yadav, Hartmut, Koeppen, Jing, Jing, Sebastian, Guelman, Mark T, Lin, Michael J, Mamounas, Jeffrey Ryan, Eastham, Patrick K, Kimes, Simon P, Williams, Alexander, Ungewickell, Derk J A, de Groot, Elisabeth G E, de Vries
Publikováno v:
Nature medicine. 28(12)
Immune checkpoint inhibitors (ICIs), by reinvigorating CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87945da94bc13f053c8fbe46b842f455
https://pubmed.ncbi.nlm.nih.gov/36471036
https://pubmed.ncbi.nlm.nih.gov/36471036
Autor:
Ilsung Chang, Johanna C. Bendell, Raymond D. Meng, Premal Patel, Sandra M. Sanabria-Bohórquez, Daniel C. Cho, Patricia LoRusso, Matthew Wongchenko, Geoffrey I. Shapiro, Iris T. Chan, Yibing Yan, Luna Musib
Publikováno v:
Investigational New Drugs. 39:163-174
Background: This Phase Ib study explored combination dosing of the allosteric MEK1/2 inhibitor cobimetinib and the ATP-competitive pan-AKT inhibitor ipatasertib. Methods: Patients with advanced solid tumors were enrolled to two dose escalation arms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9452c83b98676f0b80dbf0103f07238
https://doi.org/10.1007/s10637-020-00975-6
https://doi.org/10.1007/s10637-020-00975-6
Autor:
Shih-Min A. Huang, Howard A. Burris, Sandra M. Sanabria-Bohórquez, Johanna C. Bendell, Lars Mueller, Jean-Charles Soria, Michael Tagen, Marie-Claire Wagle, Andrea Varga, Lichuan Liu, Patricia LoRusso, Hatem Dokainish, Kwame Okrah, Elaine Murray, Antoine Hollebecque
Publikováno v:
Clinical Cancer Research. 26:1229-1236
Purpose: ERK1/2 signaling can be dysregulated in cancer. GDC-0994 is an oral inhibitor of ERK1/2. A first-in-human, phase I dose escalation study of GDC-0994 was conducted in patients with locally advanced or metastatic solid tumors. Patients and Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c40049d3f6099a4953c260cd16cfd8
https://doi.org/10.1158/1078-0432.ccr-19-2574
https://doi.org/10.1158/1078-0432.ccr-19-2574
Autor:
Kristin R. Wildsmith, Suzanne L. Baker, Rebecca D. Ray, Sandra M. Sanabria-Bohórquez, Edmond Teng, Geoffrey A. Kerchner, Michael Ward, Robby M. Weimer, Paul T. Manser
Publikováno v:
Neurobiology of Aging. 81:138-145
The regional relationships between tau positron emission tomography (PET) imaging and cognitive impairment in Alzheimer's disease (AD) remain uncertain. We examined cross-sectional associations between cognitive performance, cerebral uptake of the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7707d5bab1dd1161a7751da6678f53
https://doi.org/10.1016/j.neurobiolaging.2019.05.026
https://doi.org/10.1016/j.neurobiolaging.2019.05.026
Autor:
Suzanne L. Baker, Michael Ward, Paul T. Manser, Geoffrey A. Kerchner, Rebecca D. Ray, Sandra M. Sanabria-Bohórquez, Edmond Teng, Robby M. Weimer
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a3cc0fd5d0728e1828b84b9dfd9aca
https://doi.org/10.1016/j.jalz.2018.07.177
https://doi.org/10.1016/j.jalz.2018.07.177