Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandra M. M. Hellwig"'
Autor:
Jan G. J. van de Winkel, María Eugenia Rodríguez, Sandra M. M. Hellwig, María Laura Anabella Pérez Vidakovics, Guy A. M. Berbers
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 46(1), 39-47. Wiley
Universidad Nacional de La Plata
instacron:UNLP
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 46(1), 39-47. Wiley
Bordetella pertussis attachment to host cells is a crucial step in colonization. In this study, we investigated the specificity of antibodies, induced either by vaccination or infection, capable of reducing bacterial adherence to respiratory epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4b8f2fb70a08fc0a50e8681119aa15
https://doi.org/10.1111/j.1574-695x.2005.00001.x
https://doi.org/10.1111/j.1574-695x.2005.00001.x
Autor:
Paul J.M. Roholl, Sandra M. M. Hellwig, Jolanda P. Vermeulen, Frits R. Mooi, Jan H.G. Hoekman, Jan A. M. A. Dormans, Rob J. Vandebriel
Publikováno v:
Microbial Pathogenesis. 35:19-29
Mouse models are frequently used to study immunity and pathogenesis to Bordetella pertussis infection. To improve the understanding of the mouse infection model, the influx of host cells and B. pertussis localisation in the lungs were evaluated. Furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404345458113435c543dc0fa7e4a6155
https://doi.org/10.1016/s0882-4010(03)00087-1
https://doi.org/10.1016/s0882-4010(03)00087-1
Autor:
Sandra M. M. Hellwig, Annemiek B. van Spriel, Frits R. Mooi, Jan G. J. van de Winkel, Joop F. P. Schellekens
Publikováno v:
Infection and Immunity. 69:4846-4850
The gram-negative bacterium Bordetella pertussis is the causative agent of pertussis (whooping cough). B. pertussis expresses various virulence factors, including adhesins and toxins, which all play a role in pathogenesis. B. pertussis colonizes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b34d7bc7a4e87e201241b2b03a7f23a
https://doi.org/10.1128/iai.69.8.4846-4850.2001
https://doi.org/10.1128/iai.69.8.4846-4850.2001
Autor:
Jan G. J. van de Winkel, Frits R. Mooi, Sandra M. M. Hellwig, Wouter L. W. Hazenbos, Annemiek B. van Spriel, Hans van Oirschot
Publikováno v:
The Journal of Infectious Diseases. 183:871-879
In the absence of opsonizing antibodies, Bordetella pertussis, the causative agent of pertussis, readily binds to phagocytes via complement receptor 3 (CR3). After opsonization with antibodies, binding is mediated by IgG receptors (FcgammaR). The eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f115fa0678bea0703b45bc82a6b91f2
https://doi.org/10.1086/319266
https://doi.org/10.1086/319266
Publikováno v:
FEMS Immunology & Medical Microbiology. 26:203-207
Bordetella pertussis can attach, invade and survive intracellularly in human macrophages in vitro. To study the significance of this bacterial feature in vivo, we analyzed the presence of viable bacteria in broncho-alveolar lavage (BAL) cells of mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0715680dd3ef030f767f0c97270d3be4
https://doi.org/10.1111/j.1574-695x.1999.tb01391.x
https://doi.org/10.1111/j.1574-695x.1999.tb01391.x
Autor:
Sandra M. M. Hellwig, María Eugenia Rodriguez, Guy A. M. Berbers, Jan G. J. van de Winkel, Frits R. Mooi
Publikováno v:
The Journal of Infectious Diseases. 189:1333-1335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b0771c92fad44e7b2e90658d710878
https://doi.org/10.1086/382159
https://doi.org/10.1086/382159
Autor:
Jan A. M. A. Dormans, Rob J. Vandebriel, Eric R. Gremmer, Sandra M. M. Hellwig, Jolanda P. Vermeulen, Frits R. Mooi, Paul J.M. Roholl
Publikováno v:
Vaccine. 25(12)
While evaluating vaccine efficacy against clinical Bordetella pertussis isolates in mice, after challenge vaccinated mice showed increased lung pathology with eosinophilia, compared to challenged, non-vaccinated animals. This led us to study bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e089c754a87afed093a284b47664b35
https://pubmed.ncbi.nlm.nih.gov/17224216
https://pubmed.ncbi.nlm.nih.gov/17224216
Autor:
Frits R. Mooi, Guy A. M. Berbers, Jan G. J. van de Winkel, María Eugenia Rodríguez, Sandra M. M. Hellwig
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Pertussis, a serious infectious disease of the respiratory tract caused by Bordetella pertussis, is reemerging in vaccinated populations. Efforts to curtail this disease are hampered by limited insight into the basis of protective immunity. Opsonopha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef6858257049309c432d851367d5960
http://sedici.unlp.edu.ar/handle/10915/83288
http://sedici.unlp.edu.ar/handle/10915/83288
Autor:
M van Vugt, Takashi Saito, H.H van Ojik, Shozo Izui, Sandra M. M. Hellwig, G-J B van Ommen, Lucien A. Aarden, J. Gerber, R. Roozendaal, W.B. van den Berg, David M. Mosser, S.A da Silveira, S. de Kimpe, Andreea Ioan-Facsinay, Y.F de Jong, Christine Sedlik, Frans M. A. Hofhuis, J.G.J. van de Winkel, J. S. Verbeek, Sebastian Amigorena, P.L.E.M. van Lent
Publikováno v:
Immunity, 16, 391-402
Immunity, Vol. 16, No 3 (2002) pp. 391-402
Immunity, 16(3), 391-402. Cell Press
Immunity, 16, 3, pp. 391-402
Immunity, Vol. 16, No 3 (2002) pp. 391-402
Immunity, 16(3), 391-402. Cell Press
Immunity, 16, 3, pp. 391-402
Item does not contain fulltext The high-affinity receptor for IgG, FcgammaRI, shares its capacity to bind IgG2a immune complexes (IgG2a-IC) with the low-affinity receptor FcgammaRIII and complement factors, hampering the definition of its biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a3cae053f3ff12d83428dcebf70697
http://hdl.handle.net/2066/142819
http://hdl.handle.net/2066/142819
Autor:
María Eugenia Rodríguez, Jeanette H. W. Leusen, Daniela Flavia Hozbor, Sandra M. M. Hellwig, W. L. van der Pol, J.G.J. van de Winkel
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
The relevance of specific Abs for the induction of cellular effector functions against Bordetella pertussis was studied. IgG-opsonized B. pertussis was efficiently phagocytosed by human polymorphonuclear leukocytes (PMN). This process was mediated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bfecb1aa012bdfb942dea08b0aeba7
http://sedici.unlp.edu.ar/handle/10915/84228
http://sedici.unlp.edu.ar/handle/10915/84228