Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sandra M. Garraway"'
Autor:
Adam M. Hamilton, Lisa Blackmer-Raynolds, Yaqing Li, Sean D. Kelly, Nardos Kebede, Anna E. Williams, Jianjun Chang, Sandra M. Garraway, Shanthi Srinivasan, Timothy R. Sampson
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Spinal cord injury (SCI) results in numerous systemic dysfunctions, including intestinal dysmotility and enteric nervous system (ENS) atrophy. The ENS has capacity to recover following perturbation, yet intestinal pathologies persist. With e
Externí odkaz:
https://doaj.org/article/15c1690b33ae465794ceaf50c419c3b4
Autor:
Donald J. Noble, Rochinelle Dongmo, Shangrila Parvin, Karmarcha K. Martin, Sandra M. Garraway
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
The mechanisms of neuropathic pain after spinal cord injury (SCI) are not fully understood. In addition to the plasticity that occurs within the injured spinal cord, peripheral processes, such as hyperactivity of primary nociceptors, are critical to
Externí odkaz:
https://doaj.org/article/861a0bc70ac1483087c1a510ae712972
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Brain-derived neurotrophic factor (BDNF) signals through tropomyosin receptor kinase B (TrkB), to exert various types of plasticity. The exact involvement of BDNF and TrkB in neuropathic pain states after spinal cord injury (SCI) remains unresolved.
Externí odkaz:
https://doaj.org/article/a8935288483245c2a5aba5ff0323187c
Autor:
Joel D. Turtle, Misty M. Strain, Joshua A. Reynolds, Yung-Jen Huang, Kuan H. Lee, Melissa K. Henwood, Sandra M. Garraway, James W. Grau
Publikováno v:
Frontiers in Systems Neuroscience, Vol 12 (2018)
Pain (nociceptive) input caudal to a spinal contusion injury increases tissue loss and impairs long-term recovery. It was hypothesized that noxious stimulation has this effect because it engages unmyelinated pain (C) fibers that produce a state of ov
Externí odkaz:
https://doaj.org/article/c71010e764024f0098009f7bacb5b0cb
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
In humans, exercises involving slowed respiratory rate (SRR) counter autonomic sympathetic bias and reduce responses to stressors, including in individuals with various degrees of autonomic dysfunction. In the rat, we examined whether operant conditi
Externí odkaz:
https://doaj.org/article/f1660b3dbde9477fa4c6f184d81a559f
Autor:
Sandra M. Garraway, J. Russell Huie
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic factor family of signaling molecules. Since its discovery over three decades ago, BDNF has been identified as an important regulator of neuronal development, synaptic transmissi
Externí odkaz:
https://doaj.org/article/1fd031b79f9742e99806b1aade15bd4b
Autor:
James W Grau, J Russell Huie, Kuan H Lee, Kevin C Hoy, Yung-Jen eHuang, Joel D Turtle, Misty M. Strain, Kyle M Baumbauer, Rajesh M Miranda, Michelle A Hook, Adam R Ferguson, Sandra M. Garraway
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Research has shown that spinal circuits have the capacity to adapt in response to training, nociceptive stimulation and peripheral inflammation. These changes in neural function are mediated by physiological and neurochemical systems analogous to tho
Externí odkaz:
https://doaj.org/article/67b73a12a21b4d1fa0f3488e9e7d9fff
Autor:
James W Grau, Russell eHuie, Sandra M. Garraway, Michelle A. Hook, Eric D. Crown, Kyle M. Baumbauer, Kuan H. Lee, Kevin C. Hoy, Adam R Ferguson
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
How nociceptive signals are processed within the spinal cord, and whether these signals lead to behavioral signs of neuropathic pain, depends upon their relation to other events and behavior. Our work shows that these relations can have a lasting eff
Externí odkaz:
https://doaj.org/article/c33dd4934d824b7fae402c17305298a2
Autor:
Sandra M. Garraway
Publikováno v:
Oxford Research Encyclopedia of Neuroscience ISBN: 9780190264086
Understanding of the various types of plasticity that occur in the spinal cord, as well as understanding of spinal cord functions, has vastly improved over the past 50 years, mainly due to an increase in the number of research studies and review arti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b92311b9bb68dfd1cb3fec01f940ab1a
https://doi.org/10.1093/acrefore/9780190264086.013.384
https://doi.org/10.1093/acrefore/9780190264086.013.384
Publikováno v:
J Neurotrauma
Previously, we showed that noxious stimulation of the tail produces numerous detrimental effects after spinal cord injury (SCI), including an earlier onset and increased magnitude of mechanical hypersensitivity. Expanding on these observations, this