Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sandra M. Bovens"'
Autor:
Ryan M. Pedrigi, Vikram V. Mehta, Sandra M. Bovens, Zahra Mohri, Christian Bo Poulsen, Willy Gsell, Jordi L. Tremoleda, Leila Towhidi, Ranil de Silva, Enrico Petretto, Rob Krams
Publikováno v:
Royal Society Open Science, Vol 3, Iss 10 (2016)
The precise flow characteristics that promote different atherosclerotic plaque types remain unclear. We previously developed a blood flow-modifying cuff for ApoE−/− mice that induces the development of advanced plaques with vulnerable and stable
Externí odkaz:
https://doaj.org/article/76fe35acac5d4fd48f6f80f7901a76a6
Autor:
Pleunie van den Borne, Sander W van der Laan, Sandra M Bovens, Dave Koole, Mark C Kowala, Laura F Michael, Arjan H Schoneveld, Sander M van de Weg, Evelyn Velema, Jean-Paul de Vries, Gert J de Borst, Frans L Moll, Dominique P V de Kleijn, Paul H A Quax, Imo E Hoefer, Gerard Pasterkamp
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86522 (2014)
BackgroundLeukotriene B4 (LTB4) has been associated with the initiation and progression of atherosclerosis and abdominal aortic aneurysm (AAA) formation. However, associations of LTB4 levels with tissue characteristics and adverse clinical outcome of
Externí odkaz:
https://doaj.org/article/168e8b1d462c493483326251ca5eae6c
Autor:
Jaco J.M. Zwanenburg, Jeroen Hendrikse, Anne G. den Hartog, Dennis W. J. Klomp, Shahrzad Sepehrkhouy, Gerard Pasterkamp, Aryan Vink, Peter R. Luijten, Gert J. de Borst, Martine T. B. Truijman, W. Koning, Frans L. Moll, Sandra M. Bovens, Alexandra A. J. de Rotte
Publikováno v:
Investigative Radiology, 49(11), 749-757. LIPPINCOTT WILLIAMS & WILKINS
Objectives The objective of this study was to assess the feasibility of carotid vessel wall imaging at 7.0 for T magnetic resonance imaging (MRI) in a series of patients with a symptomatic greater than 70% stenosis of the internal carotid artery. Mat
Autor:
Ranil de Silva, Enrico Petretto, Rob Krams, Ryan M. Pedrigi, Vikram V. Mehta, Sandra M. Bovens
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:2224-2231
In this review, we summarized the effect of mechanical factors (shear and wall stress) on thin-cap fibroatheroma formation and rupture. To make this review understandable for a biology-oriented audience, we start with detailed definitions of relevant
Autor:
Takayuki Homma, Sandra M. Bovens, Nataly Maimari, Ryan M. Pedrigi, Leila Towhidi, Jennifer Frueh, Rob Krams
Publikováno v:
Cardiovascular Research. 99:334-341
This review provides an overview of the effect of blood flow on endothelial cell (EC) signalling pathways, applying microarray technologies to cultured cells, and in vivo studies of normal and atherosclerotic animals. It is found that in cultured ECs
Autor:
Ranil de Silva, Willy Gsell, Rob Krams, Christian Bo Poulsen, Jordi L. Tremoleda, Sandra M. Bovens, Zahra Mohri, Enrico Petretto, Leila Towhidi, Ryan M. Pedrigi, Vikram V. Mehta
Publikováno v:
Royal Society Open Science, Vol 3, Iss 10 (2016)
Royal Society Open Science
Pedrigi, R M, Mehta, V V, Bovens, S M, Mohri, Z, Poulsen, C B, Gsell, W, Tremoleda, J L, Towhidi, L, de Silva, R, Petretto, E & Krams, R 2016, ' Influence of shear stress magnitude and direction on atherosclerotic plaque composition ', Royal Society Open Science, vol. 3, no. 10, 160588, pp. 160588 . https://doi.org/10.1098/rsos.160588
Royal Society Open Science
Pedrigi, R M, Mehta, V V, Bovens, S M, Mohri, Z, Poulsen, C B, Gsell, W, Tremoleda, J L, Towhidi, L, de Silva, R, Petretto, E & Krams, R 2016, ' Influence of shear stress magnitude and direction on atherosclerotic plaque composition ', Royal Society Open Science, vol. 3, no. 10, 160588, pp. 160588 . https://doi.org/10.1098/rsos.160588
The precise flow characteristics that promote different atherosclerotic plaque types remain unclear. We previously developed a blood flow-modifying cuff for ApoE −/− mice that induces the development of advanced plaques with vulnerable and stable
Autor:
Pieter A. Doevendans, Sandra M. Bovens, Cees J. A. van Echteld, Rob J. van der Geest, Kees W.A. van de Kolk, Maarten J. Cramer, Bernard C. M. te Boekhorst, Ronald van ‘t Klooster, Matthijs F.M. van Oosterhout, Gerard Pasterkamp
Publikováno v:
Magnetic Resonance in Medicine, 67(6), 1764-1775
Intra-plaque hemorrhage (IPH) and lipid core, characteristics of rupture prone carotid plaques, are often visualized in vivo with MRI using T1 weighted gradient and spin echo, respectively. Increasing magnetic field strength may help to identify IPH
Autor:
Sandra M. Bovens, A.G. den Hartog, G.J. de Borst, Gerard Pasterkamp, W. Koning, F.L. Moll, J. Hendrikse
Publikováno v:
Current Cardiology Reviews
Introduction: In patients with carotid artery stenosis histological plaque composition is associated with plaque stability and with presenting symptomatology. Preferentially, plaque vulnerability should be taken into account in pre-operative work-up
Autor:
Kees W.A. van de Kolk, Marcel G.J. Nederhoff, Krista den Ouden, Sandra M. Bovens, Cees J. A. van Echteld, Bernard C. M. te Boekhorst, Arno Nauerth, Michiel ten Hove, Gerard Pasterkamp
Publikováno v:
Nmr in Biomedicine, 24(3), 307-315. John Wiley & Sons Inc.
Measurement of cardiac function is often performed in mice after, for example, a myocardial infarction. Cardiac MRI is often used because it is noninvasive and provides high temporal and spatial resolution for the left and right ventricle. In animal
Autor:
Pieter A. Doevendans, Maarten-Jan M. Cramer, M. ten Hove, Gerard Pasterkamp, Robert E. Poelmann, Sandra M. Bovens, C. J. A. van Echteld, Gustav J. Strijkers, B. C. M. te Boekhorst, C. W. A. van de Kolk, L. van der Weerd
Publikováno v:
NMR in Biomedicine, 23(8), 939-951
NMR in biomedicine, 23(8), 939-951. John Wiley and Sons Ltd
NMR in biomedicine, 23(8), 939-951. John Wiley and Sons Ltd
Single fast spin echo scans covering limited time frames are mostly used for contrast-enhanced MRI of atherosclerotic plaque biomarkers. Knowledge on inter-scan variability of the normalized enhancement ratio of plaque (NER(plaque)) and relation betw