Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sandra M Robinson"'
Autor:
Akihiko Urayama, Shinya Dohgu, Sandra M Robinson, William S Sly, Jeffery H Grubb, William A Banks
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142347 (2015)
The impermeability of the adult blood-brain barrier (BBB) to lysosomal enzymes impedes the ability to treat the central nervous system manifestations of lysosomal storage diseases. Here, we found that simultaneous stimulation of the alpha1 and alpha2
Externí odkaz:
https://doaj.org/article/07b7ca41fa7c47d6af2fb8e43771832b
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39565 (2012)
HIV-1 circulates both as free virus and within immune cells, with the level of free virus being predictive of clinical course. Both forms of HIV-1 cross the blood-brain barrier (BBB) and much progress has been made in understanding the mechanisms by
Externí odkaz:
https://doaj.org/article/dfb8ba7080424bb591625ed37f06c3e1
Publikováno v:
Clinical Rheumatology. 41:3869-3877
Educating patients about methotrexate is a core role of rheumatology nurses. We have previously reported the scoring of videoed interviews of rheumatology nurses educating patients prior to commencing methotrexate in comparison with the Calgary-Cambr
Autor:
Subinoy Rana, Margaret A. Riley, Daniel F. Moyano, Krishnendu Saha, Xiaoning Li, Hao Kong, Xinrong Zhang, Sandra M. Robinson, Rubul Mout, Vincent M. Rotello
Publikováno v:
ACS Nano
Identification of infectious bacteria responsible for biofilm-associated infections is challenging due to the complex and heterogeneous biofilm matrix. To address this issue and minimize the impact of heterogeneity on biofilm identification, we devel
Autor:
Margaret A. Riley, Akash Gupta, Ali Sahar, Daniel F. Moyano, Sandra M. Robinson, Vincent M. Rotello, Ziwen Jiang, Krishnendu Saha, Xiaoning Li
Publikováno v:
ACS Nano
We present the use of functionalized gold nanoparticles (AuNPs) to combat multi-drug-resistant pathogenic bacteria. Tuning of the functional groups on the nanoparticle surface provided gold nanoparticles that were effective against both Gram-negative
Publikováno v:
Future Medicinal Chemistry. 5:1231-1242
The importance of the human microbiome in health may be the single most valuable development in our conception of the microbial world since Pasteur’s germ theory of the 1860s. Its implications for our understanding of health and pathogenesis are pr
Autor:
Vivian Liu, Robert L. Dorit, Morgan Dennis, Christopher M. Roy, Sandra M. Robinson, Margaret A. Riley
Publikováno v:
Biochemical Society Transactions. 40:1438-1442
Pathogenic bacteria resistant to many or all antibiotics already exist. With the decline in microbiological research at pharmaceutical companies, the high rate at which resistance has evolved and spread has demanded a novel approach to addressing thi
Autor:
Sandra M. Robinson, Michael L. Niehoff, William A. Banks, Claudia Mattern, Nicole Ducharme, John E. Morley
Publikováno v:
European Journal of Pharmacology. 641:128-134
Neurosteroids hold great promise for the treatment of diseases of the central nervous system (CNS). We compared the uptake by 11 brain regions and appearance in blood of tritium-labeled pregnenolone and progesterone after intranasal and intravenous (
Autor:
Susan A. Farr, Vijaya B. Kumar, M. Paul Murphy, William A. Banks, Jessica L. Lynch, Steven N. Johnson, Michael L. Niehoff, Melissa A. Fleegal-DeMotta, Mark C. Hwang, Sandra M. Robinson, Shinya Dohgu, Laura B. Jaeger
Publikováno v:
Journal of Alzheimer's Disease. 17:553-570
Decreased clearance is the main reason amyloid-beta protein (Abeta) is increased in the brains of patients with Alzheimer's disease (AD). The neurovascular hypothesis states that this decreased clearance is caused by impairment of low density lipopro
Autor:
Shinya Dohgu, Suneetha Mare, Nuran Ercal, Suman Penugonda, Sandra M. Robinson, William A. Banks
Publikováno v:
Peptides. 28:1424-1432
The amyloid hypothesis states that amyloid beta protein (Abeta) plays a major causal role in the onset of Alzheimer's disease. Toxicity of Abeta can be modified by metal ions. Two mechanisms by which such Abeta and metal ions could interact are by en