Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sandra M Muxel"'
Autor:
Cláudia A Zago, Karina R Bortoluci, Luiz R Sardinha, Fernando D Pretel, Sheyla I Castillo-Méndez, Ana Paula Freitas do Rosário, Meire I Hiyane, Sandra M Muxel, Sérgio M Rodriguez-Málaga, Ises A Abrahamsohn, José M Álvarez, Maria Regina D'Império Lima
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29894 (2012)
Plasmodium chabaudi infection induces a rapid and intense splenic CD4(+) T cell response that contributes to both disease pathogenesis and the control of acute parasitemia. The subsequent development of clinical immunity to disease occurs concomitant
Externí odkaz:
https://doaj.org/article/3c3fd9fee8d243b5b8e3b0d536e26fee
Autor:
Maria Fernanda Laranjeira da Silva, Ricardo Andrade Zampieri, Sandra M Muxel, Stephen M Beverley, Lucile M Floeter-Winter
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34022 (2012)
In Leishmania, de novo polyamine synthesis is initiated by the cleavage of L-arginine to urea and L-ornithine by the action of arginase (ARG, E.C. 3.5.3.1). Previous studies in L. major and L. mexicana showed that ARG is essential for in vitro growth
Externí odkaz:
https://doaj.org/article/8274eb36d1b04c6c8b1acd4f000760bf
Autor:
Cláudia Emanuele Carvalho-Sousa, Sanseray eda Silveira Cruz-Machado, Eduardo Koji Tamura, Pedro A C. M. Fernandes, Luciana ePinato, Sandra M Muxel, Erika eCecon, Regina P. Markus
Publikováno v:
Frontiers in Endocrinology, Vol 2 (2011)
The pineal gland, which is the gland that translates darkness into an endocrine signal by releasing melatonin at night, is now considered a key player in the mounting of an innate immune response. Tumor necrosis factor (TNF), the first pro-inflammato
Externí odkaz:
https://doaj.org/article/8aecbbbfe05e4fdf86a275dfa71a0758
Autor:
Emerson A Castilho-Martins, Maria Fernanda Laranjeira da Silva, Marcos G dos Santos, Sandra M Muxel, Lucile M Floeter-Winter
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27818 (2011)
Leishmania (L.) amazonensis uses arginine to synthesize polyamines to support its growth and survival. Here we describe the presence of two gene copies, arranged in tandem, that code for the arginine transporter. Both copies show similar Open Reading
Externí odkaz:
https://doaj.org/article/a532e95fae4849098c2d9a715420c3bf
Autor:
Juliane C. R. Fernandes, André N. A. Gonçalves, Lucile M. Floeter-Winter, Helder I. Nakaya, Sandra M. Muxel
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
It is well established that infection with Leishmania alters the host cell’s transcriptome. Since mammalian cells have multiple mechanisms to control gene expression, different molecules, such as noncoding RNAs, can be involved in this process. Mic
Externí odkaz:
https://doaj.org/article/e24c131bbe4344cdaae74139c426d708
Autor:
Carolina M. Polonio, Patrick da Silva, Fabiele B. Russo, Brendo R. N. Hyppolito, Nagela G. Zanluqui, Cecília Benazzato, Patrícia C. B. Beltrão-Braga, Sandra M. Muxel, Jean Pierre S. Peron
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10282 (2022)
Viral infections have always been a serious burden to public health, increasing morbidity and mortality rates worldwide. Zika virus (ZIKV) is a flavivirus transmitted by the Aedes aegypti vector and the causative agent of severe fetal neuropathogenes
Externí odkaz:
https://doaj.org/article/438796f597d8469f8168c7e0609e1172
Autor:
Felipe R Floreste, Braz Titon, Stefanny C M Titon, Sandra M Muxel, Fernando R Gomes, Vania R Assis
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Synopsis Inflammation comprises alterations in glucocorticoids (in amphibians, corticosterone—CORT) and melatonin (MEL) levels, two hormones with immunomodulatory effects on cytokine production in several vertebrates. Cytokines mediate inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e8ce794287c96a7ed9e948f11ad98a
https://doi.org/10.1093/icb/icac013
https://doi.org/10.1093/icb/icac013
Autor:
Regina P Markus, Kassiano DS Sousa, Sandra M Muxel, Waldir Caldeira, Isabela L Trevisan, Marlina Córdoba-Moreno, Edson ED Ribeiro-Paz, Adriessa A Santos, Ewerton S Souza
Publikováno v:
Melatonin Research. 5:55-67
Microglia, the sentinels of the central nervous system, are responsible for the surveillance and the innate defense against pathogen or danger/damage-associated molecular patterns. The response is fine-tuned to restrain pro-inflammatory responses, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2bee0bfe5a2f80c6bc21ae4a05d819
https://doi.org/10.32794/mr112500120
https://doi.org/10.32794/mr112500120
Autor:
Felipe R. Floreste, Braz Titon, Stefanny C.M. Titon, Sandra M. Muxel, Aymam C. de Figueiredo, Fernando R. Gomes, Vania R. Assis
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The inflammatory response comprises highly orchestrated events that are conserved amongst vertebrate groups. Hepatic and splenic cytokines are major mediators of the systemic inflammatory processes. However, the liver is still neglected as an immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7d89e730b505caacb91ff7f8825bea
Autor:
Kassiano S. Sousa, Caroline L. Quiles, Sandra M. Muxel, Isabela L. Trevisan, Zulma S. Ferreira, Regina P. Markus
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The pineal gland is a key player in surveillance and defense responses. In healthy conditions, nocturnal circulating melatonin (MEL) impairs the rolling and adhesion of leukocytes to the endothelial layer. Fungi, bacteria, and pro-inflammatory cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba4cadccaff9a34d348f4541bc2a337
https://pubmed.ncbi.nlm.nih.gov/35798261
https://pubmed.ncbi.nlm.nih.gov/35798261