Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sandra M Holley"'
Autor:
Ana C Sias, Ashleigh K Morse, Sherry Wang, Venuz Y Greenfield, Caitlin M Goodpaster, Tyler M Wrenn, Andrew M Wikenheiser, Sandra M Holley, Carlos Cepeda, Michael S Levine, Kate M Wassum
Publikováno v:
eLife, Vol 10 (2021)
Adaptive reward-related decision making often requires accurate and detailed representation of potential available rewards. Environmental reward-predictive stimuli can facilitate these representations, allowing one to infer which specific rewards mig
Externí odkaz:
https://doaj.org/article/f13e8ca44fc446ad953247be2041e83e
Autor:
Jack C. Reidling, Aroa Relaño-Ginés, Sandra M. Holley, Joseph Ochaba, Cindy Moore, Brian Fury, Alice Lau, Andrew H. Tran, Sylvia Yeung, Delaram Salamati, Chunni Zhu, Asa Hatami, Carlos Cepeda, Joshua A. Barry, Talia Kamdjou, Alvin King, Dane Coleal-Bergum, Nicholas R. Franich, Frank M. LaFerla, Joan S. Steffan, Mathew Blurton-Jones, Charles K. Meshul, Gerhard Bauer, Michael S. Levine, Marie-Francoise Chesselet, Leslie M. Thompson
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 58-72 (2018)
Summary: Huntington's disease (HD) is an inherited neurodegenerative disorder with no disease-modifying treatment. Expansion of the glutamine-encoding repeat in the Huntingtin (HTT) gene causes broad effects that are a challenge for single treatment
Externí odkaz:
https://doaj.org/article/6a20e0b98a194e96bbd0862727f88f6d
Autor:
Kwang Lee, Konstantin I. Bakhurin, Leslie D. Claar, Sandra M. Holley, Natalie C. Chong, Carlos Cepeda, Michael S. Levine, Sotiris C. Masmanidis
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2438-2449.e4 (2019)
Summary: The cortex and thalamus send excitatory projections to the striatum, but little is known about how these inputs, either individually or collectively, regulate striatal dynamics during behavior. The lateral striatum receives overlapping input
Externí odkaz:
https://doaj.org/article/6687792c86704d40893e8394ebcf8d59
Autor:
Sandra M. Holley, Laurie Galvan, Talia Kamdjou, Ashley Dong, Michael S. Levine, Carlos Cepeda
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Huntington’s disease (HD) is a heritable neurological disorder that affects cognitive and motor performance in patients carrying the mutated huntingtin (HTT) gene. In mouse models of HD, previous reports showed a significant increase in spontaneous
Externí odkaz:
https://doaj.org/article/a990527128d54895b1d6aad87eb0f053
Autor:
Pierre Gressens, Alfredo Feria-Velasco, Michael S. Levine, Carlos Cepeda, Brian Chu, Don P. Dejarme, Sandra M. Holley, Payam Bokhoor, Paul M. Zhao, Alana Taniguchi, Alfonso R. Arrazola, Socorro A. R. Barajas, Araceli Espinosa-Jeffrey, Jean de Vellis
Publikováno v:
Brain Sciences, Vol 3, Iss 4, Pp 1461-1482 (2013)
Periventricular leukomalacia (PVL) is the most frequent cause of cerebral palsy and other intellectual disabilities, and currently there is no treatment. In PVL, glutamate excitotoxicity (GME) leads to abnormal oligodendrocytes (OLs), myelin deficien
Externí odkaz:
https://doaj.org/article/25b45d72de484dcfb4e9628da77a71c1
Autor:
Samuel S Pappas, Katherine Darr, Sandra M Holley, Carlos Cepeda, Omar S Mabrouk, Jenny-Marie T Wong, Tessa M LeWitt, Reema Paudel, Henry Houlden, Robert T Kennedy, Michael S Levine, William T Dauer
Publikováno v:
eLife, Vol 4 (2015)
Striatal dysfunction plays an important role in dystonia, but the striatal cell types that contribute to abnormal movements are poorly defined. We demonstrate that conditional deletion of the DYT1 dystonia protein torsinA in embryonic progenitors of
Externí odkaz:
https://doaj.org/article/9d4d4dc0369b4370b4eceffea8ccb288
Autor:
Carlos Cepeda, Sherry Wang, Michael Levine, Ashleigh K Morse, Andrew M. Wikenheiser, Tyler M Wrenn, Ana C Sias, Venuz Y. Greenfield, Kate M. Wassum, Sandra M. Holley, Caitlin M Goodpaster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b6f6ea21152e9aeddb845807d8f3785
https://doi.org/10.7554/elife.68617.sa2
https://doi.org/10.7554/elife.68617.sa2
Autor:
Ashleigh K Morse, Caitlin M Goodpaster, Carlos Cepeda, Venuz Y. Greenfield, Kate M. Wassum, Andrew M. Wikenheiser, Sandra M. Holley, Tyler M Wrenn, Ana C Sias, Sherry Wang, Michael S. Levine
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Adaptive reward-related decision making often requires accurate and detailed representation of potential available rewards. Environmental reward-predictive stimuli can facilitate these representations, allowing one to infer which specific rewards mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1108cf93a4b57b626f6057dcff1d961
http://europepmc.org/articles/PMC8266390
http://europepmc.org/articles/PMC8266390
Publikováno v:
Eur J Neurosci
The pathological hallmark of Huntington’s disease (HD) is the massive loss of striatal and cortical neurons. Until recently, it was believed that striatal interneurons were spared from degeneration. This view has changed after the demonstration tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afab3b63d606e5522a3b756d6d88ddc9
https://doi.org/10.1111/ejn.14283
https://doi.org/10.1111/ejn.14283
Autor:
Venuz Y. Greenfield, Kate M. Wassum, Caitlin M Goodpaster, Carlos Cepeda, Michael S. Levine, Tyler M Wrenn, Andrew M. Wikenheiser, Ashleigh K Morse, Sherry Wang, Ana C Sias, Sandra M. Holley
Adaptive reward-related decision making often requires accurate and detailed representation of potential available rewards. Environmental reward-predictive stimuli can facilitate these representations, allowing one to infer which specific rewards mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be35b712bf62acb37489df3ade02b3dd
https://doi.org/10.1101/2021.03.20.436233
https://doi.org/10.1101/2021.03.20.436233