Pyruvate oxidase influences the sugar utilization pattern and capsule production in Streptococcus pneumoniae.

Autor: Sandra M Carvalho, Vahid Farshchi Andisi, Henrik Gradstedt, Jolanda Neef, Oscar P Kuipers, Ana R Neves, Jetta J E Bijlsma

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68277 (2013)

Pyruvate oxidase is a key function in the metabolism and lifestyle of many lactic acid bacteria and its activity depends on the presence of environmental oxygen. In Streptococcus pneumoniae the protein has been suggested to play a major role in metab

Externí odkaz: https://doaj.org/article/17d860c78cfd458baa3ea0b96f1b3fbb

Staphylococcus epidermidis biofilms undergo metabolic and matrix remodeling under nitrosative stress

Autor: Ana S. Oliveira, Lígia M. Saraiva, Sandra M. Carvalho

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

Staphylococcus epidermidis is a commensal skin bacterium that forms host- and antibiotic-resistant biofilms that are a major cause of implant-associated infections. Most research has focused on studying the responses to host-imposed stresses on plank

Externí odkaz: https://doaj.org/article/7e4739e362a54edb902d8f3369c9f01e

Defenses of multidrug resistant pathogens against reactive nitrogen species produced in infected hosts

Autor: Sandra M, Carvalho, Jordi Zamarreño, Beas, Marco A M, Videira, Lígia M, Saraiva

Publikováno v: Advances in microbial physiology. 80

Bacterial pathogens have sophisticated systems that allow them to survive in hosts in which innate immunity is the frontline of defense. One of the substances produced by infected hosts is nitric oxide (NO) that together with its derived species lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::903e1d09092c95a35b1ff1327e02d9c1
https://pubmed.ncbi.nlm.nih.gov/35489794

Tailor-made sRNAs: a plasmid tool to control the expression of target mRNAs in Pseudomonas putida

Autor: Sandra C. Viegas, Patrícia Apura, Alexandra Peregrina, Cecília M. Arraiano, Lígia M. Saraiva, Margarida Saramago, Sandra M. Carvalho, Susana Domingues

Publikováno v: Plasmid

Pseudomonas putida is a highly attractive production system for industrial needs. However, for its improvement as a biocatalyst at the industrial level, modulation of its gene expression is urgently needed. We report the construction of a plasmid exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9541d6ecf5619ade4792f648c6eaf6ce

Metabolomics of Escherichia coli Treated with the Antimicrobial Carbon Monoxide-Releasing Molecule CORM-3 Reveals Tricarboxylic Acid Cycle as Major Target

Autor: Carlos C. Romão, Sandra M. Carvalho, Joana Marques, Lígia M. Saraiva

Publikováno v: Antimicrobial Agents and Chemotherapy
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

In the last decade, carbon monoxide-releasing molecules (CORMs) have been shown to act against several pathogens and to be promising antimicrobials. However, the understanding of the mode of action and reactivity of these compounds on bacterial cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80683c0f52c089199a6ec6681883db4a