Výsledky vyhledávání - "Sandra Mónica María Arriaga"

Complement activation and disease: protective effects of hyperbilirubinaemia

Autor: Fabián Pelusa, Sandra Mónica María Arriaga, Cecilia Lorena Basiglio, Adriana M. Almará, Aldo D. Mottino, Jaime Kapitulnik

Publikováno v: Clinical Science. 118:99-113

Complement, an important effector mechanism of the immune system, is an enzymatic cascade of approx. 30 serum proteins leading to the amplification of a specific humoral response. It can be activated through the classical or alternative pathways, or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6228af3f0d622f2b5c29bfaed2d81629
https://doi.org/10.1042/cs20080540

Zobrazit plný text záznamu

Protective role of unconjugated bilirubin on complement-mediated hepatocytolysis

Autor: Cecilia Lorena Basiglio, Marcelo G. Roma, Aldo D. Mottino, Héctor Fabián Pelusa, Sandra Mónica María Arriaga, Adriana M. Almará

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1770:1003-1010

Hyperbilirubinemia and complement-mediated immune attack on hepatocyte membrane are common features of certain hepatic diseases. To assess whether unconjugated bilirubin (UB) counteracts complement-mediated hepatocytolysis, we first generated a rabbi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293661c32f4a5d5c731d98a76f1f0c18
https://doi.org/10.1016/j.bbagen.2007.03.005

Zobrazit plný text záznamu

In vivo anti-complement effect of bilirubin-IXα

Autor: Sandra Mónica María Arriaga, Aldo D. Mottino, Adriana M. Almará

Publikováno v: Biochemical Pharmacology. 64:741-744

The effect of the IXα isomer of unconjugated bilirubin (UB) on complement-mediated intravascular hemolysis was evaluated in rats carrying naturally occurring heteroantibodies against sheep erythrocytes. Several doses of UB were administered i.v. to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129473514e50575d93f874b8d0f7ff2b
https://doi.org/10.1016/s0006-2952(02)01215-7

Zobrazit plný text záznamu

Physiological concentrations of unconjugated bilirubin prevent oxidative stress-induced hepatocanalicular dysfunction and cholestasis

Autor: Sandra Mónica María Arriaga, Marcelo G. Roma, Enrique J. Sánchez Pozzi, Flavia Daniela Toledo, Aldo D. Mottino, Andrea Carolina Boaglio, Justina E. Ochoa, Cecilia Lorena Basiglio

Publikováno v: RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR

Bilirubin is an endogenous antioxidant with cytoprotective properties, and several studies highlight its potential in the treatment of pro-oxidant diseases. We demonstrated that oxidative stress (OS), a key feature in most hepatopathies, induces chol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fc94dc61ccd1f6edec82539c9ff50d

Zobrazit plný text záznamu

Unconjugated bilirubin inhibits C1 esterase activity

Autor: Sandra Mónica María Arriaga, Aldo D. Mottino, Adriana M. Almará, Cecilia Lorena Basiglio

Publikováno v: Clinical Biochemistry. 42:919-921

Objective To evaluate if unconjugated bilirubin (UB) inhibits C1 esterase activity. Design and methods Esterase activity was evaluated by C1-mediated hydrolysis of N-acetyl- l -tyrosine ethyl ester, and binding of UB to C1r and C1s was assessed by do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4d460d5a9702d871ec47227e258a43
https://doi.org/10.1016/j.clinbiochem.2008.12.015

Zobrazit plný text záznamu

Evaluation of urinary N-acetyl-beta-D-glucosaminidase as a marker of early renal damage in patients with type 2 diabetes mellitus

Autor: Ana María Amarilla, Adriana L. Monje, Sandra Mónica María Arriaga, Adriana M. Almará, Cecilia Vicenta Paparella, Beatriz Reina Bouvet

Publikováno v: Arquivos Brasileiros de Endocrinologia & Metabologia v.58 n.8 2014
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Arquivos Brasileiros de Endocrinologia & Metabologia, Volume: 58, Issue: 8, Pages: 798-801, Published: NOV 2014
RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR

Objective: To evaluate the clinical usefulness of urinary N-acetyl-beta-D-glucosaminidase (NAG) excretion for the detection of early tubular damage in type 2 diabetes mellitus (T2DM). Subjects and methods: Thirty six patients with T2DM were divided i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe4bb6564cd411d2d3bf5eb2f092e15
https://pubmed.ncbi.nlm.nih.gov/25465599

Zobrazit plný text záznamu

Onset and evolution of nephropathy in rats with spontaneous diabetes mellitus

Autor: Juan Carlos Picena, Sandra Mónica María Arriaga, Silvana Marisa Montenegro, N. Hisano, María Cristina Tarrés, Alberto Enrique D'Ottavio, Stella Maris Martínez, Lida S. Morisoli, Stella Maris Daniele

Publikováno v: Journal of physiology and biochemistry. 56(1)

The occurrence of renal diabetic complications was studied in diabetic nonobese IIM/FmeSS (eSS) rats. The results were compared with eumetabolic Wistar rats paired by sex and age. Between 6 and 12 months of age, eSS male rats had higher fructosamine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b09a319887699fdbdd9a7c21efc6dd5
https://pubmed.ncbi.nlm.nih.gov/10879681

Zobrazit plný text záznamu

Inhibitory effect of bilirubin on complement-mediated hemolysis

Autor: Adriana M. Almará, Sandra Mónica María Arriaga, Aldo D. Mottino

Publikováno v: Biochimica et biophysica acta. 1473(2-3)

We investigated the in vitro action of the bile pigments, unconjugated bilirubin (UB) and bilirubin monoglucuronide (BMG) on complement (C) cascade reaction. Both UB and BMG inhibited hemolysis in the classical pathway (CP) in a dose-dependent manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3246655f45fca16ad8c8ee5264d601e
https://pubmed.ncbi.nlm.nih.gov/10594370

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání