Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandra M, Skovdal"'
Autor:
Sandra M Skovdal, Stig Hill Christiansen, Karen Singers Johansen, Ole Viborg, Niels Henrik Bruun, Søren Jensen-Fangel, Ida Elisabeth Holm, Thomas Vorup-Jensen, Eskild Petersen
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223647 (2019)
The developmental speed of new antimicrobials does not meet the emergence of multidrug-resistant bacteria sufficiently. A potential shortcut is assessing the antimicrobial activity of already approved drugs. Intrudingly, the antibacterial action of g
Externí odkaz:
https://doaj.org/article/7d42a65bd6d94152b8ccd00ab6ec56ba
Autor:
Lars Schreiber, Sandra M. Skovdal, Ian P. G. Marshall, Nis Pedersen Jørgensen, Rikke Louise Meyer, Niels Nørskov-Lauritsen
Publikováno v:
Meyer, R L, Skovdal, S M, Marshall, I P G, Schreiber, L, Nørskov-Lauritsen, N & Jørgensen, N P 2021, ' Genome sequence of staphylococcus epidermidis AUH4567, a clinical isolate from an infected central venous catheter ', Microbiology Resource Announcements, vol. 10, no. 12, e01254-20 . https://doi.org/10.1128/MRA.01254-20
Microbiology Resource Announcements
Microbiology Resource Announcements
Staphylococcus epidermidis is a common cause of implant-associated infections, and this is related to its ability to form biofilms. Strain-to-strain variability in biofilm formation is likely caused by genetic differences. Here, we present a draft ge
Autor:
Henning Büttner, Liva Kjær Hansen, Guanghong Zeng, Nis Pedersen Jørgensen, Rikke Louise Meyer, Sandra M. Skovdal, Diana Malskær Ivarsen, Holger Rohde
Publikováno v:
Skovdal, S M, Hansen, L K, Ivarsen, D M, Zeng, G, Büttner, H, Rohde, H, Jørgensen, N P & Meyer, R L 2021, ' Host factors abolish the need for polysaccharides and extracellular matrix-binding protein in Staphylococcus epidermidis biofilm formation ', Journal of Medical Microbiology, vol. 70, no. 3, 001287 . https://doi.org/10.1099/jmm.0.001287
Introduction. Staphylococcus epidermidis is predominant in implant-associated infections due to its capability to form biofilms. It can deploy several strategies for biofilm development using either polysaccharide intercellular adhesin (PIA), extrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dfd71446a9b5fe17c1524537f6cee0
https://pure.au.dk/portal/da/publications/host-factors-abolish-the-need-for-polysaccharides-and-extracellular-matrixbinding-protein-in-staphylococcus-epidermidis-biofilm-formation(bea19448-194f-4abd-86fe-cd3f63f28c23).html
https://pure.au.dk/portal/da/publications/host-factors-abolish-the-need-for-polysaccharides-and-extracellular-matrixbinding-protein-in-staphylococcus-epidermidis-biofilm-formation(bea19448-194f-4abd-86fe-cd3f63f28c23).html
Autor:
Sandra M, Skovdal, Liva Kjær, Hansen, Diana Malskær, Ivarsen, Guanghong, Zeng, Henning, Büttner, Holger, Rohde, Nis Pedersen, Jørgensen, Rikke L, Meyer
Publikováno v:
Journal of Medical Microbiology
Introduction Staphylococcus epidermidis is predominant in implant-associated infections due to its capability to form biofilms. It can deploy several strategies for biofilm development using either polysaccharide intercellular adhesin (PIA), extracel
Autor:
Eskild Petersen, Ole Viborg, Thomas Vorup-Jensen, Karen Singers Eiskjær Johansen, Stig Hill Christiansen, Sandra M. Skovdal, Ida Elisabeth Holm, Niels Henrik Bruun, Søren Jensen-Fangel
Publikováno v:
Skovdal, S M, Hill Christiansen, S, Singers Johansen, K, Viborg, O, Bruun, N H, Jensen-Fangel, S, Holm, I E, Vorup-Jensen, T & Petersen, J E 2019, ' Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs ', P L o S One, vol. 14, no. 10, e0223647 . https://doi.org/10.1371/journal.pone.0223647
PLoS ONE
Skovdal, S M, Christiansen, S H, Johansen, K S, Viborg, O, Bruun, N H, Jensen-Fangel, S, Holm, I E, Vorup-Jensen, T & Petersen, E 2019, ' Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs ', PLOS ONE, vol. 14, no. 10, e0223647 . https://doi.org/10.1371/journal.pone.0223647
Skovdal, S M, Christiansen, S H, Johansen, K S, Viborg, O, Bruun, N H, Jensen-Fangel, S, Holm, I E, Vorup-Jensen, T & Petersen, E 2019, ' Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs ', PLOS ONE, vol. 14, no. 10, pp. e0223647 . https://doi.org/10.1371/journal.pone.0223647
PLoS ONE, Vol 14, Iss 10, p e0223647 (2019)
PLoS ONE
Skovdal, S M, Christiansen, S H, Johansen, K S, Viborg, O, Bruun, N H, Jensen-Fangel, S, Holm, I E, Vorup-Jensen, T & Petersen, E 2019, ' Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs ', PLOS ONE, vol. 14, no. 10, e0223647 . https://doi.org/10.1371/journal.pone.0223647
Skovdal, S M, Christiansen, S H, Johansen, K S, Viborg, O, Bruun, N H, Jensen-Fangel, S, Holm, I E, Vorup-Jensen, T & Petersen, E 2019, ' Inhaled nebulized glatiramer acetate against Gram-negative bacteria is not associated with adverse pulmonary reactions in healthy, young adult female pigs ', PLOS ONE, vol. 14, no. 10, pp. e0223647 . https://doi.org/10.1371/journal.pone.0223647
PLoS ONE, Vol 14, Iss 10, p e0223647 (2019)
The developmental speed of new antimicrobials does not meet the emergence of multidrugresistant bacteria sufficiently. A potential shortcut is assessing the antimicrobial activity of already approved drugs. Intrudingly, the antibacterial action of gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b083550dc64d51b458de55a19f825cd
https://findresearcher.sdu.dk:8443/ws/files/154913975/journal.pone.0223647.pdf
https://findresearcher.sdu.dk:8443/ws/files/154913975/journal.pone.0223647.pdf
Autor:
M. Wang, Eskild Petersen, Sandra M. Skovdal, Mikkel Illemann Johansen, Nis Pedersen Jørgensen, Holger Rohde, Ryosuke Ogaki, Guanghong Zeng, Rikke Louise Meyer, Søren Jensen-Fangel
Publikováno v:
Skovdal, S M, Jørgensen, N P, Petersen, E, Jensen-Fangel, S, Ogaki, R, Zeng, G, Johansen, M I, Wang, M, Rohde, H & Meyer, R L 2018, ' Ultra-dense polymer brush coating reduces Staphylococcus epidermidis biofilms on medical implants and improves antibiotic treatment outcome ', Acta Biomaterialia, vol. 76, pp. 46-55 . https://doi.org/10.1016/j.actbio.2018.07.002
Staphylococcal biofilm formation is a severe complication of medical implants, leading to high antibiotic tolerance and treatment failure. Ultra-dense poly(ethylene glycol) (udPEG) coating resists adsorption of proteins, polysaccharides and extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b5eeb296e481a819682173ae3e7d02
https://pure.au.dk/portal/da/publications/ultradense-polymer-brush-coating-reduces-staphylococcus-epidermidis-biofilms-on-medical-implants-and-improves-antibiotic-treatment-outcome(573b29b9-ab72-47c0-82f0-325f2f4cb390).html
https://pure.au.dk/portal/da/publications/ultradense-polymer-brush-coating-reduces-staphylococcus-epidermidis-biofilms-on-medical-implants-and-improves-antibiotic-treatment-outcome(573b29b9-ab72-47c0-82f0-325f2f4cb390).html
Autor:
Thomas Vorup-Jensen, Marlene Fredborg, Michael Lykke Hvam, Rikke Louise Meyer, R.A. Murphy, Mihaela Gadjeva, Jens R. Nyengaard, Arne Möller, Stig Hill Christiansen, M. Wang, Sandra M. Skovdal, Kenneth A. Howard, Eskild Petersen, Jane C. Davies, Kristian Juul-Madsen, Uffe B. Skov Sørensen, Esben Axelgaard, Niels Nørskov-Lauritsen
Publikováno v:
Hill Christiansen, S, Murphy, R A, Juul-Madsen, K, Fredborg, M, Hvam, M L, Axelgaard, E, Skovdal, S M, Meyer, R L, Sørensen, U B S, Möller, A, Nyengaard, J R, Nørskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, K A, Davies, J C, Petersen, E & Vorup-Jensen, T 2017, ' The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria ', Scientific Reports, vol. 7, 15653 . https://doi.org/10.1038/s41598-017-15969-3
Christiansen, S H, Murphy, R A, Juul-Madsen, K, Fredborg, M, Hvam, M L, Axelgaard, E, Skovdal, S M, Meyer, R L, Sorensen, U B S, Moeller, A, Nyengaard, J R, Norskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, K A, Davies, J C, Petersen, E & Vorup-Jensen, T 2017, ' The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria ', Scientific Reports, vol. 7, 15653 . https://doi.org/10.1038/s41598-017-15969-3
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Christiansen, S H, Murphy, R A, Juul-Madsen, K, Fredborg, M, Hvam, M L, Axelgaard, E, Skovdal, S M, Meyer, R L, Sorensen, U B S, Moeller, A, Nyengaard, J R, Norskov-Lauritsen, N, Wang, M, Gadjeva, M, Howard, K A, Davies, J C, Petersen, E & Vorup-Jensen, T 2017, ' The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria ', Scientific Reports, vol. 7, 15653 . https://doi.org/10.1038/s41598-017-15969-3
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Classic drug development strategies have failed to meet the urgent clinical needs in treating infections with Gram-negative bacteria. Repurposing drugs can lead to timely availability of new antibiotics, accelerated by existing safety profiles. Glati
Autor:
Nis Pedersen Jørgensen, Kurt Fuursted, Eskild Petersen, Sandra M. Skovdal, Frederik Dagnæs-Hansen, Rikke Louise Meyer
Publikováno v:
Jørgensen, N P, Skovdal, S M, Meyer, R L, Dagnæs-Hansen, F, Fuursted, K & Petersen, E 2016, ' Rifampicin-containing combinations are superior to combinations of vancomycin, linezolid and daptomycin against Staphylococcus aureus biofilm infection in vivo and in vitro ', Pathogens and Disease, vol. 74, no. 4 . https://doi.org/10.1093/femspd/ftw019
Susceptibility to antibiotics is dramatically reduced when bacteria form biofilms. In clinical settings this has a profound impact on treatment of implant-associated infections, as these are characterized by biofilm formation. Current routine suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84bc0e01e0915d37383d539f5c9f7d5
https://pure.au.dk/portal/da/publications/rifampicincontaining-combinations-are-superior-to-combinations-of-vancomycin-linezolid-and-daptomycin-against-staphylococcus-aureus-biofilm-infection-in-vivo-and-in-vitro(bfe13419-ea0a-4e0f-8166-e72c4a7d3c19).html
https://pure.au.dk/portal/da/publications/rifampicincontaining-combinations-are-superior-to-combinations-of-vancomycin-linezolid-and-daptomycin-against-staphylococcus-aureus-biofilm-infection-in-vivo-and-in-vitro(bfe13419-ea0a-4e0f-8166-e72c4a7d3c19).html