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pro vyhledávání: '"Sandra Lopez Garces"'
Autor:
Carine Moezinia, Valerie Wong, James Watson, Lydia Nagib, Sandra Lopez Garces, Siyu Zhang, Bahja Ahmed Abdi, Florence Newton, David Abraham, Richard Stratton
Publikováno v:
Cells, Vol 12, Iss 20, p 2490 (2023)
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised by pathological processes involving autoimmunity, vasculopathy and resultant extensive skin and organ fibrosis. Recent studies have demonstrated activation and aberrant
Externí odkaz:
https://doaj.org/article/9899f88d77a34306a4c142c0ced8efa1
Autor:
Sandra Lopez Garces, Bahja Ahmed Abdi, Claire MacFadyen, Robert Smillie, Lydia Nagib, Shahi Ghani, Shivani Shah, David Abraham, Christopher Denton, Richard J Stratton
Publikováno v:
Rheumatology. 61
Background/Aims In the systemic sclerosis (SSc) microenvironment, accumulation of extracellular matrix (ECM) components induces changes in the matrix's mechanical properties, which triggers Rho/MRTFF-A activation and the downstream signalling cascade