Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sandra Larouche"'
Autor:
Jorge Ivan Alvarez, Olivia Saint-Laurent, Alisha Godschalk, Simone Terouz, Casper Briels, Sandra Larouche, Lyne Bourbonnière, Catherine Larochelle, Alexandre Prat
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 14-24 (2015)
Early changes in the normal appearing white matter of multiple sclerosis (MS) patients precede the appearance of gadolinium-enhancing lesions. Although these findings suggest blood–brain barrier (BBB) breakdown as an important feature in MS pathoge
Externí odkaz:
https://doaj.org/article/9727d0fd5e3b4d4b92a9a292fdfccc6e
Autor:
Marc Charabati, Stephanie Zandee, Antoine P Fournier, Olivier Tastet, Karine Thai, Roxaneh Zaminpeyma, Marc-André Lécuyer, Lyne Bourbonnière, Sandra Larouche, Wendy Klement, Camille Grasmuck, Fiona Tea, Bettina Zierfuss, Ali Filali-Mouhim, Robert Moumdjian, Alain Bouthillier, Romain Cayrol, Evelyn Peelen, Nathalie Arbour, Catherine Larochelle, Alexandre Prat
Publikováno v:
Brain. 146:1483-1495
The trafficking of autoreactive leucocytes across the blood–brain barrier endothelium is a hallmark of multiple sclerosis pathogenesis. Although the blood–brain barrier endothelium represents one of the main CNS borders to interact with the infil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc336d30eeb0f8febc94fb723d174b8
https://doi.org/10.1093/brain/awac389
https://doi.org/10.1093/brain/awac389
Autor:
Antoine Philippe Fournier, Olivier Tastet, Marc Charabati, Chloé Hoornaert, Lyne Bourbonnière, Wendy Klement, Sandra Larouche, Fiona Tea, Yu Chang Wang, Catherine Larochelle, Nathalie Arbour, Jiannis Ragoussis, Stephanie Zandee, Alexandre Prat
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 10(1)
Background and ObjectivesMultiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease characterized by infiltration of immune cells in multifocal areas of the CNS. The specific molecular processes allowing autoreactive immune cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e52aa9f439f6ff33b8d1764806665c
https://pubmed.ncbi.nlm.nih.gov/36446612
https://pubmed.ncbi.nlm.nih.gov/36446612
Autor:
Antoine Philippe Fournier, Stephanie Zandee, Marc Charabati, Evelyn Peelen, Olivier Tastet, Jorge Ivan Alvarez, Hania Kebir, Lyne Bourbonnière, Sandra Larouche, Boaz Lahav, Wendy Klement, Fiona Tea, Alain Bouthillier, Robert Moumdjian, Romain Cayrol, Pierre Duquette, Marc Girard, Catherine Larochelle, Nathalie Arbour, Alexandre Prat
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 9(6)
Background and ObjectivesIn multiple sclerosis (MS), peripheral immune cells use various cell trafficking molecules to infiltrate the CNS where they cause damage.The objective of this study was to investigate the involvement of coxsackie and adenovir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f5a7ef261445a44c80ab69af1cdfd7
https://pubmed.ncbi.nlm.nih.gov/36241608
https://pubmed.ncbi.nlm.nih.gov/36241608
Autor:
Marc, Charabati, Camille, Grasmuck, Soufiane, Ghannam, Lyne, Bourbonnière, Antoine P, Fournier, Marc-André, Lécuyer, Olivier, Tastet, Hania, Kebir, Rose-Marie, Rébillard, Chloé, Hoornaert, Elizabeth, Gowing, Sandra, Larouche, Olivier, Fortin, Camille, Pittet, Ali, Filali-Mouhim, Boaz, Lahav, Robert, Moumdjian, Alain, Bouthillier, Marc, Girard, Pierre, Duquette, Romain, Cayrol, Evelyn, Peelen, Francisco J, Quintana, Jack P, Antel, Alexander, Flügel, Catherine, Larochelle, Nathalie, Arbour, Stephanie, Zandee, Alexandre, Prat
Publikováno v:
Science translational medicine. 14(626)
The migration of circulating leukocytes into the central nervous system (CNS) is a key driver of multiple sclerosis (MS) pathogenesis. The monoclonal antibody natalizumab proved that pharmaceutically obstructing this process is an effective therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da92b6686c7d77550fe45ec88df640a6
https://pubmed.ncbi.nlm.nih.gov/35119940
https://pubmed.ncbi.nlm.nih.gov/35119940
Autor:
Marc Charabati, Camille Grasmuck, Soufiane Ghannam, Lyne Bourbonnière, Antoine P. Fournier, Marc-André Lécuyer, Olivier Tastet, Hania Kebir, Rose-Marie Rébillard, Chloé Hoornaert, Elizabeth Gowing, Sandra Larouche, Olivier Fortin, Camille Pittet, Ali Filali-Mouhim, Boaz Lahav, Robert Moumdjian, Alain Bouthillier, Marc Girard, Pierre Duquette, Romain Cayrol, Evelyn Peelen, Francisco J. Quintana, Jack P. Antel, Alexander Flügel, Catherine Larochelle, Nathalie Arbour, Stephanie Zandee, Alexandre Prat
Publikováno v:
Science Translational Medicine. 14
DICAM contributes to the pathogenesis of autoimmune neuroinflammation by promoting the migration of T H 17 lymphocytes across the blood-brain barrier.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::345d3e0341e90f94b714f22cffd8f83f
https://doi.org/10.1126/scitranslmed.abj0473
https://doi.org/10.1126/scitranslmed.abj0473
Autor:
Pierre Duquette, Sandra Larouche, Alexandre Prat, Marc Girard, Catherine Lachance, Tessa Dhaeze, Robert Moumdjian, Xavier Ayrignac, Rose-Marie Rébillard, Josée Poirier, Alain Bouthillier, Lyne Bourbonnière, Evelyn Peelen, Catherine Larochelle, Camille Grasmuck, Laurence Tremblay, Boaz Lahav, Stephanie Zandee
Publikováno v:
Cellular & Molecular Immunology. 16:652-665
CD70 is the unique ligand of CD27 and is expressed on immune cells only upon activation. Therefore, engagement of the costimulatory CD27/CD70 pathway is solely dependent on upregulation of CD70. However, the T cell-intrinsic effect and function of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9e4e9fcf39dc010bda28f8a3967a57e
https://doi.org/10.1038/s41423-018-0198-5
https://doi.org/10.1038/s41423-018-0198-5
Autor:
Tessa Dhaeze, Alexandre Prat, Boaz Lahav, Laure Michel, Marc-André Lécuyer, Pierre Duquette, Lyne Bourbonnière, Evelyn Peelen, Camille Grasmuck, Amit Bar-Or, Robert Moumdjian, Marc Charabati, Alain Bouthillier, Jennifer L. Gommerman, Sandra Larouche, Stephanie Zandee, Jorge I. Alvarez, Rui Li
Publikováno v:
Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2019, 11 (518), pp.eaaw0475. ⟨10.1126/scitranslmed.aaw0475⟩
Science Translational Medicine, 2019, 11 (518), pp.eaaw0475. ⟨10.1126/scitranslmed.aaw0475⟩
Science Translational Medicine, American Association for the Advancement of Science, 2019, 11 (518), pp.eaaw0475. ⟨10.1126/scitranslmed.aaw0475⟩
Science Translational Medicine, 2019, 11 (518), pp.eaaw0475. ⟨10.1126/scitranslmed.aaw0475⟩
International audience; The presence of B lymphocyte-associated oligoclonal immunoglobulins in the cerebrospinal fluid is a classic hallmark of multiple sclerosis (MS). The clinical efficacy of anti-CD20 therapies supports a major role for B lymphocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c7104436698d37d4d0d6e29f8a9d04
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02397748
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02397748
Autor:
Sandra Larouche, Marc André Lécuyer, Alexandre Prat, Catherine Lachance, Stephanie Zandee, Lyne Bourbonnière, Tessa Dhaeze, Laurence Tremblay, Rose Marie Rébillard, Olivia Saint-Laurent, Camille Grasmuck
TCR(1640) mice, which have a T cell receptor (TCR) directed against MOG(92–106), spontaneously develop experimental autoimmune encephalomyelitis. Female mice mostly develop a relapsing-remitting (RR) course and have a higher incidence of disease, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de10e8d367593dd0e8e046ad78e8725
https://europepmc.org/articles/PMC6483003/
https://europepmc.org/articles/PMC6483003/
Autor:
Josée Poirier, Jean-Philippe Ouimet, Evelyn Peelen, Romain Cayrol, Alain Bouthillier, Marc Charabati, Lamia Hachehouche, Elizabeth Gowing, Pierre Duquette, Stephanie Zandee, Lyne Bourbonnière, Robert Moumdjian, Nathalie Arbour, Alexandre Prat, Olivier Tastet, Florent Lemaître, Marc-André Lécuyer, Sandra Larouche, Boaz Lahav, Bieke Broux
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
Objective To investigate the involvement of interleukin (IL)-26 in neuroinflammatory processes in multiple sclerosis (MS), in particular in blood-brain barrier (BBB) integrity. Methods Expression of IL-26 was measured in serum, CSF, in vitro differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9900c4d5f1b35a44a1fa7e5a94d7820
https://doi.org/10.1212/nxi.0000000000000870
https://doi.org/10.1212/nxi.0000000000000870