Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Sandra Laakmann"'
1
Minimally invasive closed-chest ultrasound-guided substance delivery into the pericardial space in mice
Autor: Lisa Fortmüller, G. Breves, Sandra Laakmann, Ilaria Piccini, Paulus Kirchhof, Larissa Fabritz, Wilhelm Schmitz, Stephanie Grote-Wessels
Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology
Organ-directed gene transfer remains an attractive method for both gaining a better understanding of heart disease and for cardiac therapy. However, virally mediated transfer of gene products into cardiac cells requires prolonged exposure of the myoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34bce83537245f4c4c076aca67acd96
http://europepmc.org/articles/PMC3570759
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2
PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression
Autor: Ilaria Piccini, Peter C. Kahr, H. H. Scheld, Sander Verheule, Ulrich Schotten, Paulus Kirchhof, Lisa Fortmueller, Nigel A. Brown, Heinrich Rotering, Sandra Laakmann, Larissa Fabritz, Sven Kaese, Ismail Vokshi
Publikováno v: Circulation: Cardiovascular Genetics; Vol 4
Circulation : Cardiovascular Genetics, 4(2), 123-U84. LIPPINCOTT WILLIAMS & WILKINS
Background— Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult hearts express PITX2 and whether variation in expression affects car
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fdf55b0c8c1441bc3523627c96a069
https://doi.org/10.1161/CIRCGENETICS.110.958058
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3
Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3
Autor: Dierk Damke, Daniela Volkery, Günter Breithardt, Michael R. Franz, Burkhard Riemann, Peter Carmeliet, Andreas Blana, Lisa Fortmüller, Uwe Kirchhefer, Paulus Kirchhof, Edward Carmeliet, Larissa Fabritz, Johannes Steinfurt, Kathrin Theis, Michael Schäfers, Sven Hermann, Elena Aleynichenko, Markus Emmerich, Sebastian Maier, Sandra Laakmann, Susann G. Kaufmann
Publikováno v: Cardiovascular Research
Aims Clinical observations in patients with long QT syndrome carrying sodium channel mutations (LQT3) suggest that bradycardia caused by parasympathetic stimulation may provoke torsades de pointes (TdP). β-Adrenoceptor blockers appear less effective
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec05fd34228bd43db8f53f807710de3a
https://doi.org/10.1093/cvr/cvq029
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7
Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability
Autor: Edward Carmeliet, Uwe Kirchhefer, Kelly A. van Bragt, Ilaria Piccini, Ulrich Schotten, Dierk Damke, Peter Carmeliet, Andreas Blana, Günter Breithardt, Sandra Laakmann, Sander Verheule, Paulus Kirchhof, Larissa Fabritz, Sven Kaese, Stanley Nattel, Lisa Fortmüller, Jens Eckstein
Publikováno v: Heart Rhythm, 7(12), 1862-1869. Elsevier Science
BACKGROUND Patients with long QT syndrome (LQTS) are at increased risk not only for ventricular arrhythmias but also for atrial pathology including atrial fibrillation (AF). Some patients with "lone" AF carry Na(+)-channel mutations. OBJECTIVE The pu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0585df2037d1cc03814702806b297539
https://cris.maastrichtuniversity.nl/en/publications/cb7d9d61-ba51-43d3-9f68-c4eca01df8b0
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Plný text Recenzováno Digitální knihovna AV ČR
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