Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sandra L. Pfister"'
Autor:
William B. Campbell, Adeniyi Michael Adebesin, Anja Herrnreiter, John R. Falck, Tamas Kriska, Sandra L. Pfister
Publikováno v:
Hypertension. 79:104-114
12/15-LO (12/15-lipoxygenase), encoded by Alox15 gene, metabolizes arachidonic acid to 12(S)-HETE (12-hydroxyeicosatetraenoic acid). Macrophages are the major source of 12/15-LO among immune cells, and 12/15-LO plays a crucial role in development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19fc3bd6ed2f5f6fda33375746a5b8d6
https://doi.org/10.1161/hypertensionaha.121.17824
https://doi.org/10.1161/hypertensionaha.121.17824
Autor:
Sang-Kyu Park, Benjamin A Falck, Kathryn M. Gauthier, Anja Herrnreiter, John R. Falck, William B. Campbell, Sandra L. Pfister
Publikováno v:
The Journal of biological chemistry. 293(27)
Endothelium-derived epoxyeicosatrienoic acids (EETs) have numerous vascular activities mediated by G protein–coupled receptors. Long-chain free fatty acids and EETs activate GPR40, prompting us to investigate the role of GPR40 in some vascular EET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27dd22e5b000d18286392f1cbf9d5d2
https://pubmed.ncbi.nlm.nih.gov/29777058
https://pubmed.ncbi.nlm.nih.gov/29777058
Publikováno v:
Oncotarget
Protein-protein interactions can increase or decrease its therapeutic target activity and the determining factors involved, however, are largely unknown. Here, we report that tyrosine-dephosphorylation of epidermal growth factor receptor (EGFR) incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dedfd4fd2a2c796442fdcf6a95cd2feb
https://doi.org/10.18632/oncotarget.3645
https://doi.org/10.18632/oncotarget.3645
15(S)-Hydroxyeicosa-(5Z,8Z,11Z,13E)-tetraenoic acid (15(S)-HETE) is a metabolite of arachidonic acid that elicits a number of biological effects including vasoconstriction and angiogenesis. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid (HETE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf1729ef6638bb7e8b6601a1ccaad62
https://europepmc.org/articles/PMC4893888/
https://europepmc.org/articles/PMC4893888/
Autor:
Yongmei Zhang, Candice D. Fike, Mark R. Kaplowitz, Judy L. Aschner, James C. Slaughter, Sandra L. Pfister
Publikováno v:
Pediatric Research. 70:136-141
Reactive oxygen species (ROS) have been implicated in the pathogenesis of pulmonary hypertension. ROS might mediate vascular responses, at least in part, by stimulating prostanoid production. Our goals were to determine whether the effect of ROS on v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124e8d50a81c7961070b06b8e1c6bb9d
https://doi.org/10.1203/pdr.0b013e3182207ce7
https://doi.org/10.1203/pdr.0b013e3182207ce7
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 300:H2064-H2071
This study explored the hypothesis that a portion of angiotensin II-induced contractions is dependent on superoxide generation and release of a previously unidentified arachidonic acid metabolite that activates vascular smooth muscle thromboxane rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8a8523de5bee009802f0584916b500
https://doi.org/10.1152/ajpheart.01135.2010
https://doi.org/10.1152/ajpheart.01135.2010
Autor:
Sandra L. Pfister
Publikováno v:
Hypertension. 57:825-832
Pulmonary arterial hypertension is characterized by elevated pulmonary artery pressure and vascular resistance. In women the incidence is 4 fold greater than that in men. Studies suggest sustained vasoconstriction is a factor in increased vascular re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc68e1e2edf4a697573fa1354d55fefc
https://doi.org/10.1161/hypertensionaha.110.168716
https://doi.org/10.1161/hypertensionaha.110.168716
Autor:
Ying Gao, Lewis B. Somberg, Elizabeth R. Jacobs, Timothy F. Lowry, Sandra L. Pfister, Meetha Medhora
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 141(2):425-431
Objectives Our model of a systemic–pulmonary shunt exhibits enhanced reactivity of pulmonary arteries contralateral to a localized shunt between the left lower lobe pulmonary artery and aorta relative to those of ipsilateral or control pulmonary ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e23e4487dd92f8e28b92c775de37d1
Autor:
Heng Zeng, Judy L. Aschner, James C. Slaughter, Naila Rashida Frye, Mark R. Kaplowitz, Sandra L. Pfister, Yongmei Zhang, Candice D. Fike
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 299:H1190-H1204
Aberrant interactions between heat shock protein (Hsp)90 and its client proteins could contribute to pulmonary hypertension. We tested the hypotheses that 1) the interaction between Hsp90 and its known client protein, endothelial nitric oxide synthas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d247b38caf3d050f2b2d39d246afb1
https://doi.org/10.1152/ajpheart.01207.2009
https://doi.org/10.1152/ajpheart.01207.2009
Autor:
Sandra L. Pfister
Publikováno v:
Prostaglandins & Other Lipid Mediators. 87:54-61
An increased synthesis of thromboxane (TX) A(2) is associated with a number of cardiovascular diseases including atherosclerosis, unstable angina and hypertension. We previously identified a subgroup of NZW rabbits in which isolated arteries failed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4359b2df72fba29b13556299452ab1e6
https://doi.org/10.1016/j.prostaglandins.2008.08.002
https://doi.org/10.1016/j.prostaglandins.2008.08.002