Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Sandra L. Hofmann"'
Autor:
Hemanth R. Nelvagal, Samantha L. Eaton, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takahashi, Steven Q. Le, Rachel Nesbitt, Joshua T. Dearborn, Nicholas Siano, Ana C. Puhl, Patricia I. Dickson, Gerard Thompson, Fraser Murdoch, Paul M. Brennan, Mark Gray, Stephen N. Greenhalgh, Peter Tennant, Rachael Gregson, Eddie Clutton, James Nixon, Chris Proudfoot, Stefano Guido, Simon G. Lillico, C. Bruce A. Whitelaw, Jui-Yun Lu, Sandra L. Hofmann, Sean Ekins, Mark S. Sands, Thomas M. Wishart, Jonathan D. Cooper
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
CLN1 disease, also called infantile neuronal ceroid lipofuscinosis (NCL) or infantile Batten disease, is a fatal neurodegenerative lysosomal storage disorder resulting from mutations in the CLN1 gene encoding the soluble lysosomal enzyme palmitoyl-pr
Externí odkaz:
https://doaj.org/article/fb7adb2cd6174d5a9c38555ece25def7
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 4 (2016)
A 70-year-old African American female with a past medical history significant for chronic bilateral shoulder pain and reported sickle cell trait presented with acute-onset bilateral thoracolumbar pain radiating to her left arm. Two days after admissi
Externí odkaz:
https://doaj.org/article/b24ca4bf5b52402c8dd82cc9addccaf3
Autor:
Jui-Yun Lu, Sandra L. Hofmann
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1352-1357 (2006)
Much is now understood concerning the synthesis of prenylated and palmitoylated proteins, but what is known of their metabolic fate? This review details metabolic pathways for the lysosomal degradation of S-fatty acylated and prenylated proteins. Cen
Externí odkaz:
https://doaj.org/article/9669acde9ec74620a2c7a5aaee279303
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 2, Pp 314-323 (2005)
The neuronal ceroid lipofuscinoses are a newly-recognized group of lysosomal storage disorders in which neurodegeneration predominates. The pathophysiological basis for this is unknown. In the current paper, we sought to determine whether neurons tha
Externí odkaz:
https://doaj.org/article/7cc42ab725fd402db39139b614b2a52e
Autor:
Sandra L. Hofmann, John D. Minna, Ignacio I. Wistuba, Eugene P. Frenkel, Jaime Rodriguez-Canales, Hui Liu, Luc Girard, Jill E. Larsen, Ryan M. Carstens, Kenneth E. Huffman, Chunli Shao, Jui-Yun Lu, Hui Tian
Supplementary Figures S1-S5 and Supplementary Methods. Figure S1: Screening of a large number of NSCLC lines for sensitivity to siRNAs directed against 23 DHHC palmitoyltransferases. Figure S2: Membrane localization of DHHC5 in DHHC5 and DHHS mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a14431f6d2462aed52d13a6bfd01c6
https://doi.org/10.1158/1541-7786.22515022
https://doi.org/10.1158/1541-7786.22515022
Autor:
Sandra L. Hofmann, John D. Minna, Ignacio I. Wistuba, Eugene P. Frenkel, Jaime Rodriguez-Canales, Hui Liu, Luc Girard, Jill E. Larsen, Ryan M. Carstens, Kenneth E. Huffman, Chunli Shao, Jui-Yun Lu, Hui Tian
Tables S1-S3 Table S1. Non-small cell lung cancer cell lines used in the current study. Table S2. Clinicopathological characteristics for 194 primary patient samples (NSCLC). Table S3. siRNA used in screen (purchased from Qiagen) in 53 NSCLC lines an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f402e2febf59551fc67d9a7ab7f3995
https://doi.org/10.1158/1541-7786.22515019
https://doi.org/10.1158/1541-7786.22515019
Autor:
Nicholas C.J. Lee, Sean Yates, Siayareh Rambally, Ravindra Sarode, Ibrahim F. Ibrahim, Yu-Min Shen, Sandra L. Hofmann, Natalie Bavli
Publikováno v:
Blood. 140:2693-2694
Publikováno v:
British Journal of Haematology. 196
Publikováno v:
eLife, Vol 2 (2013)
In fibroblasts, large Ca transients activate massive endocytosis (MEND) that involves membrane protein palmitoylation subsequent to mitochondrial permeability transition pore (PTP) openings. Here, we characterize this pathway in cardiac muscle. Myocy
Externí odkaz:
https://doaj.org/article/9ff487c1759e425a9fcbed3a88b83b6b
Autor:
Hemanth R. Nelvagal, Samantha L. Eaton, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takahashi, Steven Q. Le, LaRachel Nesbitt, Joshua T. Dearborn, Ana C. Puhl, Patricia I. Dickson, Paul M. Brennan, Gerard Thompson, Sandra L. Hofmann, Sean Ekins, Mark S. Sands, Thomas M. Wishart, Jonathan D. Cooper
Publikováno v:
Molecular Genetics and Metabolism. 135:S88