Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandra Koska"'
Autor:
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S Goody, Matthias P Müller, Daniel Rauh
Publikováno v:
eLife, Vol 12 (2023)
Mutations within Ras proteins represent major drivers in human cancer. In this study, we report the structure-based design, synthesis, as well as biochemical and cellular evaluation of nucleotide-based covalent inhibitors for KRasG13C, an important o
Externí odkaz:
https://doaj.org/article/a1d132d50aee4a898fe7a71dc2e28751
Autor:
Tobias Grabe, Kirujan Jeyakumar, Janina Niggenaber, Tom Schulz, Sandra Koska, Silke Kleinbölting, Michael Edmund Beck, Matthias P. Müller, Daniel Rauh
Publikováno v:
ACS Medicinal Chemistry Letters. 14:591-598
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9101f7e1b187a745d5e89ba9a5de2194
https://doi.org/10.1021/acsmedchemlett.2c00514
https://doi.org/10.1021/acsmedchemlett.2c00514
Autor:
Axel Pahl, Jie Liu, Sohan Patil, Soheila Rezaei Adariani, Beate Scholermann, Jana Bonowski, Sandra Koska, Sonja Sievers, Jens Warmers, Slava Ziegler, Herbert Waldmann
The identification of bioactive small molecules is at the heart of chemical biology and medicinal research. The screening for modulators of disease-relevant targets and phenotypes is the first step on the way to new drugs. Therefore, large compound l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dce5b2917cea0fd68fc989942354ceb
https://doi.org/10.1101/2023.05.31.542818
https://doi.org/10.1101/2023.05.31.542818
Autor:
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S Goody, Matthias P Müller, Daniel Rauh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fef2d901ca844d77790e3ee8bb9e4e
https://doi.org/10.7554/elife.82184.sa2
https://doi.org/10.7554/elife.82184.sa2
Autor:
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning, Stefano Maffini, Helge Vatheuer, Paul Czodrowski, Roger S. Goody, Matthias P. Müller, Daniel Rauh
Mutations within Ras proteins represent major drivers in human cancer. In this study, we report the structure-based design, synthesis, as well as biochemical and cellular evaluation of nucleotide-based covalent inhibitors for KRasG13C, an important o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8059c0af079cd564489957a2783e2d4
https://doi.org/10.1101/2022.07.25.501348
https://doi.org/10.1101/2022.07.25.501348
Autor:
Xie, Jianing1 (AUTHOR), Pahl, Axel1,2 (AUTHOR), Krzyzanowski, Adrian1,3 (AUTHOR), Krupp, Anna4 (AUTHOR), Liu, Jie1 (AUTHOR), Koska, Sandra1 (AUTHOR), Schölermann, Beate1 (AUTHOR), Zhang, Ruirui1 (AUTHOR), Bonowski, Jana1 (AUTHOR), Sievers, Sonja1,2 (AUTHOR), Strohmann, Carsten4 (AUTHOR), Ziegler, Slava1 (AUTHOR), Grigalunas, Michael1 (AUTHOR) michael.grigalunas@mpi-dortmund.mpg.de, Waldmann, Herbert1,3 (AUTHOR) herbert.waldmann@mpi-dortmund.mpg.de
Publikováno v:
Angewandte Chemie. 11/27/2023, Vol. 135 Issue 48, p1-12. 12p.
Autor:
Goebel, Lisa, Kirschner, Tonia, Koska, Sandra, Rai, Amrita, Janning, Petra, Maffini, Stefano, Vatheuer, Helge, Czodrowski, Paul, Goody, Roger S., Müller, Matthias P., Rauh, Daniel
Publikováno v:
eLife; 3/27/2023, p1-22, 22p
Publikováno v:
Cancer Weekly; 4/11/2023, p1266-1266, 1p