Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sandra Korge"'
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000792 (2020)
A ubiquitous feature of the circadian clock across life forms is its organization as a network of cellular oscillators, with individual cellular oscillators within the network often exhibiting considerable heterogeneity in their intrinsic periods. Th
Externí odkaz:
https://doaj.org/article/58d54a6a14b846cc8988396d7f4b15e9
Autor:
Sandra Korge, Bert Maier, Franziska Brüning, Lea Ehrhardt, Thomas Korte, Matthias Mann, Andreas Herrmann, Maria S Robles, Achim Kramer
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007189 (2018)
Circadian clocks are molecular timekeeping mechanisms that allow organisms to anticipate daily changes in their environment. The fundamental cellular basis of these clocks is delayed negative feedback gene regulation with PERIOD and CRYPTOCHROME cont
Externí odkaz:
https://doaj.org/article/d3586331872d44469d329fc1d365e3a7
Autor:
Marta del Olmo, Florian Spörl, Sandra Korge, Karsten Jürchott, Matthias Felten, Astrid Grudziecki, Jan de Zeeuw, Claudia Nowozin, Hendrik Reuter, Thomas Blatt, Hanspeter Herzel, Dieter Kunz, Achim Kramer, Bharath Ananthasubramaniam
Publikováno v:
NAR Genomics and Bioinformatics. 4
The skin is the largest human organ with a circadian clock that regulates its function. Although circadian rhythms in specific functions are known, rhythms in the proximal clock output, gene expression, in human skin have not been thoroughly explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fab9aa3ffc943d56f953afcac251829
https://doi.org/10.1093/nargab/lqac097
https://doi.org/10.1093/nargab/lqac097
Autor:
Marta del Olmo, Florian Spörl, Sandra Korge, Karsten Jürchott, Matthias Felten, Astrid Grudziecki, Jan de Zeeuw, Claudia Nowozin, Hendrik Reuter, Thomas Blatt, Hanspeter Herzel, Dieter Kunz, Achim Kramer, Bharath Ananthasubramaniam
The skin is the largest human organ with a circadian clock that regulates its function. Although circadian rhythms in specific functions are known, rhythms in the proximal clock output, gene expression, in human skin have not been thoroughly explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de13a1d64adcf8cae8a3f67c2764305e
https://doi.org/10.1101/2022.06.03.494693
https://doi.org/10.1101/2022.06.03.494693
Autor:
Thomas Wallach, Achim Kramer, Nicholas C. Fiorenza, Mechthild Rosing, Bert Maier, Sabrina Klemz, Sandra Korge, Erik D. Herzog, Roman Klemz, Anna K. Fritzsche, Ralf Stanewsky, Irem Kaymak
Publikováno v:
Genes Dev
In all organisms with circadian clocks, post-translational modifications of clock proteins control the dynamics of circadian rhythms, with phosphorylation playing a dominant role. All major clock proteins are highly phosphorylated, and many kinases h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac814709cbbccf4c96a0142c2183ab9f
https://europepmc.org/articles/PMC8336894/
https://europepmc.org/articles/PMC8336894/
Autor:
Tamer Oruc, Marc Kraft, Natalie Jankowski, Jörg Niewöhner, Stefan Hildebrand, Astrid Trachterna, Simon Gallinger, Milena D. Bister, Urte Heitman, Robert Downes, Sandra Korge
Publikováno v:
Current Directions in Biomedical Engineering, Vol 5, Iss 1, Pp 277-279 (2019)
Pressure ulcers (decubiti) are one of the most frequent side effects in the palliative care setting. Terminally ill and dying people have multiple comorbidities resulting in a high risk to develop pressure ulcers. These skin lesions are caused by pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d132ec16050f62852fd6706c53569387
https://doi.org/10.1515/cdbme-2019-0070
https://doi.org/10.1515/cdbme-2019-0070
Publikováno v:
PLoS Biology
PLoS Biology, Vol 18, Iss 8, p e3000792 (2020)
PLoS Biology, Vol 18, Iss 8, p e3000792 (2020)
A ubiquitous feature of the circadian clock across life forms is its organization as a network of cellular oscillators, with individual cellular oscillators within the network often exhibiting considerable heterogeneity in their intrinsic periods. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2795a17c3aa3fdc3c565e5e8d40c500b
https://pubmed.ncbi.nlm.nih.gov/33052900
https://pubmed.ncbi.nlm.nih.gov/33052900
A ubiquitous feature of circadian clocks across life forms is its organization as a network of coupled cellular oscillators. Individual cellular oscillators of the network often exhibit a considerable degree of heterogeneity in their intrinsic period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0694373d74d1a824ceee499e6296e0c6
https://doi.org/10.1101/731075
https://doi.org/10.1101/731075
Autor:
Andreas Herrmann, Thomas Korte, Franziska Brüning, Maria S. Robles, Achim Kramer, Matthias Mann, Sandra Korge, Bert Maier, Lea Ehrhardt
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 1, p e1007189 (2018)
PLoS Genetics, Vol 14, Iss 1, p e1007189 (2018)
Circadian clocks are molecular timekeeping mechanisms that allow organisms to anticipate daily changes in their environment. The fundamental cellular basis of these clocks is delayed negative feedback gene regulation with PERIOD and CRYPTOCHROME cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbe296ed2f0aedc1f90c953092d670c
https://hdl.handle.net/21.11116/0000-0000-B195-F21.11116/0000-0000-B197-D21.11116/0000-0000-B198-C
https://hdl.handle.net/21.11116/0000-0000-B195-F21.11116/0000-0000-B197-D21.11116/0000-0000-B198-C
Publikováno v:
Journal of Biological Rhythms. 30:389-395
Targeted genome editing using CRISPR/Cas9 is a relatively new, revolutionary technology allowing for efficient and directed alterations of the genome. It has been widely used for loss-of-function studies in animals and cell lines but has not yet been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47de49aa5b5abb474f3fe6ab6543f45b
https://doi.org/10.1177/0748730415597519
https://doi.org/10.1177/0748730415597519