Výsledky vyhledávání - "Sandra Koernig"

Akademický článek

Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates

Autor: Cédric Vonarburg, Marius Loetscher, Martin O. Spycher, Alain Kropf, Marlies Illi, Sharon Salmon, Sean Roberts, Karin Steinfuehrer, Ian Campbell, Sandra Koernig, Joseph Bain, Monika Edler, Ulrich Baumann, Sylvia Miescher, Dennis W. Metzger, Alexander Schaub, Fabian Käsermann, Adrian W. Zuercher

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)

Abstract Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Dise

Externí odkaz: https://doaj.org/article/14ff40a2a8dd402c98faa7221f7dd197

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Akademický článek

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells

Publikováno v: Stem Cell Reports, Vol 7, Iss 3, Pp 571-582 (2016)

Hematopoiesis is a multistage process involving the differentiation of stem and progenitor cells into distinct mature cell lineages. Here we present Haemopedia, an atlas of murine gene-expression data containing 54 hematopoietic cell types, covering

Externí odkaz: https://doaj.org/article/0e4686e0159f47788abe1fd7d9831621

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Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

Autor: Milica Ng, Ildem Sanli, Adrian Zuercher, Pawel Pelczar, Wy Ching Ng, Fabian Käsermann, Cédric Vonarburg, Alexander Schaub, Charley Mackenzie-Kludas, Ian K. Campbell, Lorena E. Brown, Monther Alhamdoosh, Sandra Koernig, Roland Zehnder, Marius Loetscher

Publikováno v: Mucosal Immunology

Recurrent and persistent airway infections remain prevalent in patients with primary immunodeficiency (PID), despite restoration of serum immunoglobulin levels by intravenous or subcutaneous plasma-derived IgG. We investigated the effectiveness of di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4716cf962d707803fc16b343723dd
https://doi.org/10.1038/s41385-019-0167-z

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Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates

Autor: Adrian Zuercher, Sean Roberts, Joseph Bain, Dennis W. Metzger, Fabian Käsermann, Alain Kropf, Marlies Illi, Marius Loetscher, Monika Edler, Karin Steinfuehrer, Sandra Koernig, Sylvia Miescher, Ulrich Baumann, Alexander Schaub, Martin O. Spycher, Sharon L. Salmon, Ian K. Campbell, Cédric Vonarburg

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Respiratory Research

Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Disease or wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb9756a20139aa9fd30fc2462510ccc
https://doi.org/10.1186/s12931-019-1057-3

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Treating murine inflammatory diseases with an anti-erythrocyte antibody

Autor: Danielle Marjoram, Alan H. Lazarus, Ian K. Campbell, Michael Kim, Patrick J. Mott, Jennifer Brasseit, Chao Ching Jen, Andrew R. Crow, Rick Kapur, Simrat S Kahlon, Adrian Zuercher, Yoelys Cruz-Leal, Sandra Koernig, Issaka Yougbaré, Fabian Käsermann, Ramsha Khan, Alaa Amash, Heyu Ni, John W. Semple

Publikováno v: Science translational medicine, 11(506):eaau8217. American Association for the Advancement of Science

Treatment of autoimmune and inflammatory diseases typically involves immune suppression. In an opposite strategy, we show that administration of the highly inflammatory erythrocyte-specific antibody Ter119 into mice remodels the monocyte cellular lan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3775f874a82cc199d63ec89e8a03f0
https://pure.amc.nl/en/publications/treating-murine-inflammatory-diseases-with-an-antierythrocyte-antibody(07971f1e-2181-4261-89c4-21ccc0858001).html

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rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 200(8)

Activation of Fc receptors and complement by immune complexes is a common important pathogenic trigger in many autoimmune diseases and so blockade of these innate immune pathways may be an attractive target for treatment of immune complex-mediated pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa3a7164c9d87af7b6e29ca887ff09b
https://pubmed.ncbi.nlm.nih.gov/29760434

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Evaluation of the bioactivity of influenza vaccine strains in vitro suggests that the introduction of new strains in the 2010 Southern Hemisphere Trivalent Influenza Vaccine is associated with adverse events

Autor: Milica Ng, Steve Rockman, Dorit Becher, Allison Dyson, Eugene Maraskovsky, Megan Barnden, Adriana Baz Morelli, Sandra Koernig, Mimi L.K. Tang, Martin J. Pearse

Publikováno v: Vaccine. 32(30):3861-3868

In Australia, during the 2010 Southern Hemisphere (SH) influenza season, there was an unexpected increase in post-marketing adverse event reports of febrile seizures (FS) in children under 5 years of age shortly after vaccination with the CSL trivale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8aaf111c8d8474506221e0a424d16e2

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ISCOMATRIX: a novel adjuvant for use in prophylactic and therapeutic vaccines against infectious diseases

Autor: Anabel Silva, Debbie Drane, Eugene Maraskovsky, Sandra Koernig, Dorit Becher, Adriana Baz Morelli

Publikováno v: Journal of Medical Microbiology. 61:935-943

The ISCOMATRIX adjuvant has antigen delivery and presentation properties as well as immunomodulatory capabilities, which combine to provide enhanced and accelerated immune responses. The responses are broad, including a range of subclasses of antibod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942b17037b51d2495e9fb57c3b549e33
https://doi.org/10.1099/jmm.0.040857-0

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The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62

Autor: Cecile Voisine, Sandra Koernig, C. A. Egan, Jean Langhorne, William Harnett, Tracey J. Lamb

Publikováno v: Parasite Immunology. 29:271-276

ES-62 is a phosphorylcholine-containing glycoprotein secreted by filarial nematodes. This molecule has been shown to reduce the severity of inflammation in collagen-induced arthritis (CIA) in mice, a model of rheumatoid arthritis, via down-regulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6a9723aafe0ae0c6c0b8fecea2d959
https://doi.org/10.1111/j.1365-3024.2007.00941.x

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