Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandra Kling"'
Autor:
Renata Vieira de Sá, Emma Sudria-Lopez, Marta Cañizares Luna, Oliver Harschnitz, Dianne M. A. van den Heuvel, Sandra Kling, Danielle Vonk, Henk-Jan Westeneng, Henk Karst, Lauri Bloemenkamp, Suzy Varderidou-Minasian, Domino K. Schlegel, Mayte Mars, Mark H. Broekhoven, Nicky C. H. van Kronenburg, Youri Adolfs, Vamshidhar R. Vangoor, Rianne de Jongh, Tijana Ljubikj, Lianne Peeters, Sabine Seeler, Enric Mocholi, Onur Basak, David Gordon, Fabrizio Giuliani, Tessa Verhoeff, Giel Korsten, Teresa Calafat Pla, Morten T. Venø, Jørgen Kjems, Kevin Talbot, Michael A. van Es, Jan H. Veldink, Leonard H. van den Berg, Pavol Zelina, R. Jeroen Pasterkamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Intermediate-length repeat expansions in ATAXIN-2 (ATXN2) are the strongest genetic risk factor for amyotrophic lateral sclerosis (ALS). At the molecular level, ATXN2 intermediate expansions enhance TDP-43 toxicity and pathology. However, wh
Externí odkaz:
https://doaj.org/article/f542924285bc411ab2ef82b8bba3d188
Autor:
Suzy Varderidou-Minasian, Bert M. Verheijen, Oliver Harschnitz, Sandra Kling, Henk Karst, W. Ludo van der Pol, R. Jeroen Pasterkamp, Maarten Altelaar
Publikováno v:
ACS Omega, Vol 6, Iss 51, Pp 35375-35388 (2021)
Externí odkaz:
https://doaj.org/article/e82a0a9c2a524d3fa27fb3e05b82551b
Autor:
Paul R. Ormel, Renata Vieira de Sá, Emma J. van Bodegraven, Henk Karst, Oliver Harschnitz, Marjolein A. M. Sneeboer, Lill Eva Johansen, Roland E. van Dijk, Nicky Scheefhals, Amber Berdenis van Berlekom, Eduardo Ribes Martínez, Sandra Kling, Harold D. MacGillavry, Leonard H. van den Berg, René S. Kahn, Elly M. Hol, Lot D. de Witte, R. Jeroen Pasterkamp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Brain organoid models reported to date lack cells of mesodermal origin, such as microglia. Here, the authors demonstrate that mature microglia-like cells are generated within their cerebral organoid model, providing new avenues for studying human mic
Externí odkaz:
https://doaj.org/article/0f43c1e80fff44ada197169a4b75a7dc
Autor:
R. Jeroen Pasterkamp, Sandra Kling, Oliver Harschnitz, W. Ludo van der Pol, Henk Karst, Wouter van Rheenen, Leonard H. van den Berg, Marc D. Jansen, Lotte Vlam, Renata Vieira de Sá, Corette J. Wierenga, Lill Eva Johansen
Publikováno v:
Annals of Neurology. 80:71-88
OBJECTIVE: We investigated the pathogenicity of immunoglobulin M (IgM) anti-GM1 antibodies in serum from patients with multifocal motor neuropathy (MMN) using human induced pluripotent stem cell (iPSC)-derived motor neurons (MNs). METHODS: iPSCs were
Autor:
Renata Vieira de Sá, Lot de Witte, Henk Karst, Paul R. Ormel, Eduardo Ribes Martínez, Leonard H. van den Berg, R. Jeroen Pasterkamp, Emma J. van Bodegraven, Sandra Kling, Harold D. MacGillavry, Roland van Dijk, Elly M. Hol, Nicky Scheefhals, Lill Eva Johansen, Marjolein A. M. Sneeboer, René S. Kahn, Oliver Harschnitz, Amber Berdenis van Berlekom
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications [E], 9(1). Nature Publishing Group
Nature Communications, 9(1):4167. Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications [E], 9(1). Nature Publishing Group
Nature Communications, 9(1):4167. Nature Publishing Group
Cerebral organoids are 3D stem cell-derived models that can be utilized to study the human brain. The current consensus is that cerebral organoids consist of cells derived from the neuroectodermal lineage. This limits their value and applicability, a
Publikováno v:
Tehnički Vjesnik, Vol 30, Iss 2, Pp 416-425 (2023)
The paper deals with the isogeometric analysis (IGA) of active composite laminates with piezoelectric layers. IGA is a special formulation of the finite element method (FEM) that aims at seamless integration of geometric and finite element modelling.
Externí odkaz:
https://doaj.org/article/b566eb9316c6438b920f1d22d1f39c24
Autor:
Oliver, Harschnitz, Leonard H, van den Berg, Lill Eva, Johansen, Marc D, Jansen, Sandra, Kling, Renata, Vieira de Sá, Lotte, Vlam, Wouter, van Rheenen, Henk, Karst, Corette J, Wierenga, R Jeroen, Pasterkamp, W Ludo, van der Pol
Publikováno v:
Annals of neurology. 80(1)
We investigated the pathogenicity of immunoglobulin M (IgM) anti-GM1 antibodies in serum from patients with multifocal motor neuropathy (MMN) using human induced pluripotent stem cell (iPSC)-derived motor neurons (MNs).iPSCs were generated from fibro
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008784 (2021)
The interior of a eukaryotic cell is a highly complex composite material which consists of water, structural scaffoldings, organelles, and various biomolecular solutes. All these components serve as obstacles that impede the motion of vesicles. Hence
Externí odkaz:
https://doaj.org/article/f7483c7413a9485cafe17a621089dffa
Autor:
Serhat Aygün, Sandra Klinge
Publikováno v:
Polymers, Vol 12, Iss 11, p 2575 (2020)
The present contribution deals with the thermomechanical modeling of the strain-induced crystallization in unfilled polymers. This phenomenon significantly influences mechanical and thermal properties of polymers and has to be taken into consideratio
Externí odkaz:
https://doaj.org/article/5470483589c04fe88605cdfe76a96415
Publikováno v:
Applied Sciences, Vol 8, Iss 10, p 1948 (2018)
Selective laser melting process has already been developed for many metallic materials, including steel, aluminum, and titanium. The quasistatic properties of these materials have been found to be comparable or even better than their conventionally-m
Externí odkaz:
https://doaj.org/article/052669cf018d4bca8aa8dc74d3234920