Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sandra Keir"'
Autor:
Clive P. Page, Carmen Lorena Robaina Cabrera, Nick Clarkson, Nick Horniman, Sandra Keir-Rudman
Publikováno v:
Pulmonary pharmacologytherapeutics. 69
Introduction/background and purpose Studies with Cannabis Sativa plant extracts and endogenous agonists of cannabinoid receptors have demonstrated anti-inflammatory, bronchodilator , and antitussive properties in the airways of allergic and non-aller
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf059692ae0d86c50d383e4cf992d0d
https://pubmed.ncbi.nlm.nih.gov/34082108
https://pubmed.ncbi.nlm.nih.gov/34082108
Autor:
Sandra Keir, David A. Jackson, Clive P. Page, Francis Man, Anthony R.M. Coates, Varsha Kanabar, Yanira Riffo-Vasquez, Rodrigo Rodrigues e‐Lacerda, Valerie Corrigall
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 50(4)
Background\ud We have previously demonstrated that Mycobacteria tuberculosis chaperonin 60.1 inhibits leucocyte diapedesis and bronchial hyperresponsiveness in a murine model of allergic lung inflammation.\ud \ud Methods\ud In the present study, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4edb07490edfe3366201900dd61187
https://pubmed.ncbi.nlm.nih.gov/31845415
https://pubmed.ncbi.nlm.nih.gov/31845415
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 33:25-31
Airways obstruction induced by intravenously administered bradykinin is abolished in guinea pigs treated with indomethacin, which has been shown to be, at least in part thromboxane dependent. As thromboxane is primarily generated from circulating pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de46e05e726fb8c1cfae42b19b3d919
https://doi.org/10.1016/j.pupt.2015.05.004
https://doi.org/10.1016/j.pupt.2015.05.004
Autor:
Simon C. Pitchford, Paolo Gresele, Stefania Momi, Sandra Keir, Giorgia Manni, Richard T. Amison, Abigail Morris, Clive P. Page
Background Clinical studies reveal platelet activation in patients with asthma, allergic rhinitis, and eczema. This is distinct from platelet aggregation, which is critical for the maintenance of hemostasis and in which a role for platelet purinergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b05caaa5c82c0d7d40b86cacfe5e3d7
http://hdl.handle.net/11391/1326107
http://hdl.handle.net/11391/1326107
Publikováno v:
British Journal of Pharmacology. 147:720-728
Inhaled adenosine induces airway obstruction in asthmatic but not healthy subjects, a phenomenon that is also observed in various animal species when they are immunised to a relevant antigen, but which does not occur in naive animals. The purpose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70f1f7dfdb55c42fd4617ef5ad472566
https://doi.org/10.1038/sj.bjp.0706663
https://doi.org/10.1038/sj.bjp.0706663
Publikováno v:
Journal of Allergy and Clinical Immunology. 110:388-394
It has recently been suggested that regular treatment with racemic beta(2)-adrenoceptor agonists might result in bronchial hyperresponsiveness (BHR) to a range of spasmogens, and this might be due to adverse effects of the distomer.We sought to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11ca70fd09046386a398fa591ed074f
https://doi.org/10.1067/mai.2002.126661
https://doi.org/10.1067/mai.2002.126661
Autor:
Richard T, Amison, Stefania, Momi, Abigail, Morris, Giorgia, Manni, Sandra, Keir, Paolo, Gresele, Clive P, Page, Simon C, Pitchford
Publikováno v:
The Journal of allergy and clinical immunology. 135(2)
Clinical studies reveal platelet activation in patients with asthma, allergic rhinitis, and eczema. This is distinct from platelet aggregation, which is critical for the maintenance of hemostasis and in which a role for platelet purinergic receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19af2673bbf42981713716adb8d5ee3b
https://pubmed.ncbi.nlm.nih.gov/25445826
https://pubmed.ncbi.nlm.nih.gov/25445826
Autor:
Carla Cicala, Beatrice Severino, Giuseppe Cirino, Domenico Spina, Rosaria Meli, Clive P. Page, Sandra Keir
Publikováno v:
British Journal of Pharmacology. 132:1229-1234
1. Protease activated receptor-2 (PAR2) is a seven transmembrane domain G protein coupled receptor proteolytically activated. PAR2, together with other PARs, can be also activated by peptides mimicking the sequence of the receptor tethered ligand. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b325a2ddc33ca94cc1c6d7f58239337e
https://doi.org/10.1038/sj.bjp.0703934
https://doi.org/10.1038/sj.bjp.0703934
Publikováno v:
Pulmonary pharmacologytherapeutics. 26(3)
(−)-Δ9 -Tetrahydrocannabinol has been demonstrated to have beneficial effects in the airways, but its psychoactive effects preclude its therapeutic use for the treatment of airways diseases . In the present study we have investigated the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aca171a5a0f2a45c7b3e726ae00e52b
https://pubmed.ncbi.nlm.nih.gov/23428645
https://pubmed.ncbi.nlm.nih.gov/23428645
Publikováno v:
King's College London
Background Animal models of allergy and bronchial hyperresponsiveness (BHR) are useful in researching pulmonary diseases and evaluating drug effects on the airways. Neonatally immunised rabbits exhibit several features of asthma as adults, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0908ebc3bbc5dfeb277075b7ab07f8
https://pubmed.ncbi.nlm.nih.gov/21854860
https://pubmed.ncbi.nlm.nih.gov/21854860