Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sandra K. Kirkman"'
Publikováno v:
Toxicology and Applied Pharmacology. 59:355-363
Wy-13,876, 3-(p-chlorophenyl)-2,3-dihydro-3-hydroxythiazolo[3,2a]benzimidazole-2-acetic acid, causes enlargement of the thyroids of rats and dogs. Radioactivity was accumulated in the thyroids, but not in other tissues of dogs given the 14C-labeled d
Autor:
Hans W. Ruelius, Frank W. Janssen, Anthony J Coleman, Sandra K. Kirkman, Peter J Southgate, William J. Jusko, Soong T. Chiang
Publikováno v:
Clinical Pharmacology and Therapeutics. 27:352-362
Absorption, biotransformation, excretion, and kinetics of oxaprozin (4,5-diphenyl-2-oxazolepropionic acid) were examined in subjects after an oral dose of 14C-oxaprozin alone as well as before, during, and after long-term administration of unlabeled
Publikováno v:
Analytical Biochemistry. 30:217-221
A method for quantitation of cycloleucine in biological fluids is described. Cycloleucine is oxidized to cyclopentanone by ninhydrin. The cyclopentanone formed is extracted into chloroform and determined by GLC. The method is accurate, convenient, ra
Publikováno v:
Biochemical Pharmacology. 22:1379-1383
Publikováno v:
Journal of Pharmaceutical Sciences. 69:794-796
A high-performance liquid chromatographic method for the analysis of oxaprozin in the presence of ketoprofen (the internal standard) was developed. Sample preparation involved macro- and microextraction procedures. An octadecylsilane reversed-phase s
Autor:
Hans W. Ruelius, Sandra K. Kirkman, Emily M. Young, Frank W. Janssen, H.P.K. Agersborg, Walter E. Tucker
Publikováno v:
Toxicology and applied pharmacology. 29(1)
A nephrotoxic effect was noted in male but not in female COBS-CD rats chronically treated with 1-aminocyclohexanecarboxylic acid (ACHC), a metabolite of 6-(1-aminocyclohexanecarboxamido)penicillanic acid (cyclacillin). The renal changes were qualitat
Publikováno v:
Biochemistry. 6(10)
Publikováno v:
Biochemistry. 6(5)
Autor:
Hans W. Ruelius, Sandra K. Kirkman, E M Young, R.T. Schillings, Frank W. Janssen, S.F. Sisenwine
Publikováno v:
Biochemical Pharmacology. 34:451-452