Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sandra J. Saouaf"'
Autor:
Geng Zhang, Sandra J. Saouaf, Mark I. Greene, Wayne W. Hancock, Yuan Shen, Narumi Furuuchi, Bin Li
Publikováno v:
Experimental and Molecular Pathology. 87:99-104
Collagen-induced arthritis (CIA) is an established mouse model of disease with hallmarks of clinical rheumatoid arthritis. Histone/protein deacetylase inhibitors (HDACi) are known to inhibit the pathogenesis of CIA and other models of autoimmune dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730603c1824ead5daa6e410a330f51d9
https://doi.org/10.1016/j.yexmp.2009.06.003
https://doi.org/10.1016/j.yexmp.2009.06.003
Autor:
Mark I. Greene, Wayne W. Hancock, Makoto Katsumata, Yuan Shen, Qiang Wang, Arabinda Samanta, Sandra J. Saouaf, Xiaomin Song, Geng Zhang, Kathryn Bembas, Bin Li
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14023-14027
Expression of FOXP3, a potent gene-specific transcriptional repressor, in regulatory T cells is required to suppress autoreactive and alloreactive effector T cell function. Recent studies have shown that FOXP3 is an acetylated protein in a large nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55203f36d6cdd82183d9dd1b24090e03
https://doi.org/10.1073/pnas.0806726105
https://doi.org/10.1073/pnas.0806726105
Publikováno v:
Experimental and Molecular Pathology. 83:283-295
The immunoglobulin superfamily member CD147 plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development. Here we review the current understanding of CD147 expression and protein interactions with regard to CD147 functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58b34256ee713bd6ef80affdd0197ed
https://doi.org/10.1016/j.yexmp.2007.08.014
https://doi.org/10.1016/j.yexmp.2007.08.014
Autor:
Kathryn T. Iacono, Arabinda Samanta, Xiaomin Song, Mark I. Greene, Wayne W. Hancock, Sandra J. Saouaf, Samik Basu, James L. Riley, Yuan Shen, Ran Tao, Kathryn Bembas, Bin Li
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4571-4576
The forkhead family protein FOXP3 acts as a repressor of transcription and is both an essential and sufficient regulator of the development and function of regulatory T cells. The molecular mechanism by which FOXP3-mediated transcriptional repression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda000af61d32124ffc7026cc4012b72
https://doi.org/10.1073/pnas.0700298104
https://doi.org/10.1073/pnas.0700298104
Autor:
Patrick J. Brennan, Mark I. Greene, Avinash Bhandoola, Sandra J. Saouaf, Jamey D. Marth, Steven J. Van Dyken, Bin Li
Publikováno v:
International Immunology. 18:627-635
Decreased binding by the 6C10 auto-antibody serves as a unique marker for CD4+ T cell unresponsiveness after the induction of T cell tolerance in Vbeta8.1 TCR transgenic mice. We further define the nature of the epitope recognized by the 6C10 antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0426e85f43d2b5b90a76a6a54a3d0369
https://doi.org/10.1093/intimm/dxh344
https://doi.org/10.1093/intimm/dxh344
Publikováno v:
Immunologic Research. 28:193-200
Our studies on the immune response to foreign antigens are reviewed as they relate to the mechanisms of peripheral immune tolerance. The activation of suppressor T cells by distinct modes of antigen presentation is discussed. Through the use of mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c9e56bb2aa27134775cdd93e16f194
https://doi.org/10.1385/ir:28:3:193
https://doi.org/10.1385/ir:28:3:193
Publikováno v:
Journal of Biological Chemistry. 270:27072-27078
To elucidate interactions occurring between B cell protein tyrosine kinases and the signaling components of the B cell antigen receptor, we have co-transfected into COS cells individual tyrosine kinases together with chimeric cell surface receptors c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d594a7c11bd9f50d8f1d96e60410c92a
https://doi.org/10.1074/jbc.270.45.27072
https://doi.org/10.1074/jbc.270.45.27072
Publikováno v:
Clinical Immunology and Immunopathology. 76:S151-S157
The nonreceptor protein tyrosine kinases (PTKs) have been grouped into 10 different enzyme families based on predicted amino acid sequences. As the number of enzymes belonging to the nonreceptor class of PTK is increasing, one challenge is to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f7ca17ec4502977c75eda263677c53
https://doi.org/10.1016/s0090-1229(95)90036-5
https://doi.org/10.1016/s0090-1229(95)90036-5
Autor:
Joseph Fargnoli, Owen N. Witte, Sandra J. Saouaf, Joseph B. Bolen, R. B. Rowley, S. A. Kut, Anne L. Burkhardt, Satoshi Tsukada, Sandeep Mahajan
Publikováno v:
Proceedings of the National Academy of Sciences. 91:9524-9528
We evaluated in WEHI 231 B cells the time-dependent responses of Lyn, Blk, Btk, Syk, and three members of the Jak family of protein tyrosine kinases following antibody-mediated surface engagement of the B-cell antigen receptor. Our results show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aa452c89d725b4b6a55ca02385984b
https://doi.org/10.1073/pnas.91.20.9524
https://doi.org/10.1073/pnas.91.20.9524
Autor:
Qiang Wang, Xiao Yun Zhao, Kathryn Bembas, Bin Li, Xiaomin Song, Hongtao Zhang, Zhaocai Zhou, Zheng Cai, Alan Berezov, Yuan Shen, Mark I. Greene, Sandra J. Saouaf
Publikováno v:
The Epigenetics of Autoimmune Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ff100d7ed92e82d77157587b56d723f
https://doi.org/10.1002/9780470743553.ch21
https://doi.org/10.1002/9780470743553.ch21
