Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Sandra J Shefelbine"'
Publikováno v:
MethodsX, Vol 11, Iss , Pp 102428- (2023)
Lamellar bone formed in individuals with moderate and severe osteogenesis imperfecta (OI) is often composed of lamellae that are structurally abnormal. Measuring the thickness of these lamellae can be helpful in assessing the effect of specific colla
Externí odkaz:
https://doaj.org/article/4ea5a361b12d4fea87af14efa7cea38d
Autor:
Alessandra Carriero, Behzad Javaheri, Neda Bassir Kazeruni, Andrew A Pitsillides, Sandra J Shefelbine
Publikováno v:
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
ABSTRACT Bone adapts its architecture to the applied load; however, it is still unclear how bone mechano‐adaptation is coordinated and why potential for adaptation adjusts during the life course. Previous animal models have suggested strain as the
Externí odkaz:
https://doaj.org/article/c6b20a1cd93d4f998dbbe7aca1ef1e06
Autor:
Timothy J Duerr, Ester Comellas, Eun Kyung Jeon, Johanna E Farkas, Marylou Joetzjer, Julien Garnier, Sandra J Shefelbine, James R Monaghan
Publikováno v:
eLife, Vol 9 (2020)
Measuring nascent macromolecular synthesis in vivo is key to understanding how cells and tissues progress through development and respond to external cues. Here we perform in vivo injection of alkyne- or azide-modified analogs of thymidine, uridine,
Externí odkaz:
https://doaj.org/article/c22f47b3523048f3b88c251ed6bba1d0
Publikováno v:
JBMR Plus, Vol 3, Iss 9, Pp n/a-n/a (2019)
ABSTRACT Disuse osteoporosis is a serious, secondary consequence of spinal cord injury (SCI). Numerous pharmacological and exercise therapies have been implemented to mitigate bone loss after SCI. However, these therapies have not been shown to impro
Externí odkaz:
https://doaj.org/article/64b86ccb99f245a088f69218a59065d0
Autor:
Behzad Javaheri, Mark Hopkinson, Blandine Poulet, Andrea S Pollard, Sandra J Shefelbine, Yu-Mei Chang, Philippa Francis-West, George Bou-Gharios, Andrew A Pitsillides
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159657 (2016)
Tissue inhibitor of metalloproteinases-3 (TIMP-3) regulates extracellular matrix via its inhibition of matrix metalloproteinases and membrane-bound sheddases. Timp-3 is expressed at multiple sites of extensive tissue remodelling. This extends to bone
Externí odkaz:
https://doaj.org/article/8c729571bc684693be70e8d6a47be8d6
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Structure model index (SMI) is widely used to measure rods and plates in trabecular bone. It exploits the change in surface curvature that occurs as a structure varies from spherical (SMI = 4), to cylindrical (SMI = 3) to planar (SMI = 0). The most i
Externí odkaz:
https://doaj.org/article/46330134353249bd9b3a91cdfc84da86
Autor:
Kai Yu Zhang, Alexis Wiktorowicz-Conroy, John R Hutchinson, Michael Doube, Michal Klosowski, Sandra J Shefelbine, Anthony M J Bull
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34619 (2012)
We present a three dimensional (3D) morphometric modelling study of the scapulae of Felidae, with a focus on the correlations between forelimb postures and extracted scapular shape variations. Our shape modelling results indicate that the scapular in
Externí odkaz:
https://doaj.org/article/db68971a4de1422e83addb8f65aa334b
Autor:
Gemma N Jones, Dafni Moschidou, Tamara-Isabel Puga-Iglesias, Katarzyna Kuleszewicz, Maximilien Vanleene, Sandra J Shefelbine, George Bou-Gharios, Nicholas M Fisk, Anna L David, Paolo De Coppi, Pascale V Guillot
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43395 (2012)
Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications and cell-based therapies, but their collection is restricted ethically and technically. In contrast, the placenta is a pote
Externí odkaz:
https://doaj.org/article/9daf098975aa48ffa18a8f9bc460f3f2
Publikováno v:
Current Osteoporosis Reports. 21:105-116
Purpose of the Review Bone adapts structure and material properties in response to its mechanical environment, a process called mechanoadpatation. For the past 50 years, finite element modeling has been used to investigate the relationships between b
Reaction-diffusion systems have been widely used to model pattern formation in biological systems. However, the emergence of Turing patterns in three-dimensional (3D) domains remains relatively unexplored. A few studies on this topic have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ba4f794ccb37122752582f0c94424f9
https://doi.org/10.1101/2023.03.29.534782
https://doi.org/10.1101/2023.03.29.534782