Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sandra Iurescia"'
Autor:
Giordano Perini, Valentina Palmieri, Andrea Papait, Alberto Augello, Daniela Fioretti, Sandra Iurescia, Monica Rinaldi, Elsa Vertua, Antonietta Silini, Riccardo Torelli, Angela Carlino, Teresa Musarra, Maurizio Sanguinetti, Ornella Parolini, Marco De Spirito, Massimiliano Papi
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100986- (2024)
Surgically addressing tumors poses a challenge, requiring a tailored, multidisciplinary approach for each patient based on the unique aspects of their case. Innovative therapeutic regimens combined to reliable reconstructive methods can contribute to
Externí odkaz:
https://doaj.org/article/fc8bc366561840078d9df5c859cb908b
Autor:
Daniela Fioretti, Mario Ledda, Sandra Iurescia, Raffaella Carletti, Cira Di Gioia, Maria Grazia Lolli, Rodolfo Marchese, Antonella Lisi, Monica Rinaldi
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 30 (2023)
Background: The regeneration of severe traumatic muscle injuries is an unsolved medical need that is relevant for civilian and military medicine. In this work, we produced a critically sized nonhealing muscle defect in a mouse model to investigate mu
Externí odkaz:
https://doaj.org/article/7deac05d873241c4acaf2179df0f5207
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The innate immune system provides the first line of defense against pathogen infection though also influences pathways involved in cancer immunosurveillance. The innate immune system relies on a limited set of germ line-encoded sensors termed pattern
Externí odkaz:
https://doaj.org/article/558fa7e44a7b4732a212c17337db24dd
Publikováno v:
Cancers (Basel) 12 (2020). doi:10.3390/cancers12113158
info:cnr-pdr/source/autori:Sandra Iurescia, Daniela Fioretti and Monica Rinaldi/titolo:The Innate Immune Signalling Pathways: Turning RIG-I Sensor Activation Against Cancer/doi:10.3390%2Fcancers12113158/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers, Vol 12, Iss 3158, p 3158 (2020)
Cancers
info:cnr-pdr/source/autori:Sandra Iurescia, Daniela Fioretti and Monica Rinaldi/titolo:The Innate Immune Signalling Pathways: Turning RIG-I Sensor Activation Against Cancer/doi:10.3390%2Fcancers12113158/rivista:Cancers (Basel)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Cancers, Vol 12, Iss 3158, p 3158 (2020)
Cancers
Simple Summary The clinical success in immunotherapy has been remarkable, and, at the same time, disappointing. The immune context of the tumour microenvironment has an influence on tumour initiation, response, and therapy. It is an urgent matter to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3332f4f711514e4428b5cb598be7ef9
https://publications.cnr.it/doc/435329
https://publications.cnr.it/doc/435329
Publikováno v:
Molecular neurobiology (Online) (2017). doi:10.1007/s12035-016-0304-6
info:cnr-pdr/source/autori:Iurescia S., Seripa D., Rinaldi M./titolo:Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression/doi:10.1007%2Fs12035-016-0304-6/rivista:Molecular neurobiology (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Iurescia S., Seripa D., Rinaldi M./titolo:Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression/doi:10.1007%2Fs12035-016-0304-6/rivista:Molecular neurobiology (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume
Serotonin (5-HT) is a neurotransmitter that regulates fundamental aspects of brain development, physiology and behaviour. The serotonin transporter (5-HTT) is deputized to the reuptake of 5-HT from the intersynaptic space in the presynaptic neurons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e974601b83a4f71cfa1a5873fcbc20da
https://doi.org/10.1007/s12035-016-0304-6
https://doi.org/10.1007/s12035-016-0304-6
Publikováno v:
Recent patents on anti-cancer drug discovery
13 (2018): 2–17. doi:10.2174/1574892812666171030163804
info:cnr-pdr/source/autori:Iurescia S.; Fioretti D.; Rinaldi M./titolo:Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy/doi:10.2174%2F1574892812666171030163804/rivista:Recent patents on anti-cancer drug discovery (Print)/anno:2018/pagina_da:2/pagina_a:17/intervallo_pagine:2–17/volume:13
13 (2018): 2–17. doi:10.2174/1574892812666171030163804
info:cnr-pdr/source/autori:Iurescia S.; Fioretti D.; Rinaldi M./titolo:Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy/doi:10.2174%2F1574892812666171030163804/rivista:Recent patents on anti-cancer drug discovery (Print)/anno:2018/pagina_da:2/pagina_a:17/intervallo_pagine:2–17/volume:13
Background Nucleic acid sensing is an essential strategy employed by the innate immune system to detect both pathogen-derived nucleic acids and self-DNA released by host apoptotic or necrotic cells. The presence of nucleic acids that gain access to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44923ee952317e201ca71c1f37a8992f
https://doi.org/10.2174/1574892812666171030163804
https://doi.org/10.2174/1574892812666171030163804
Publikováno v:
Molecular neurobiology (Online) 53 (2016): 5510–5526. doi:10.1007/s12035-015-9409-6
info:cnr-pdr/source/autori:Iurescia S., Seripa D., Rinaldi M./titolo:Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants/doi:10.1007%2Fs12035-015-9409-6/rivista:Molecular neurobiology (Online)/anno:2016/pagina_da:5510/pagina_a:5526/intervallo_pagine:5510–5526/volume:53
info:cnr-pdr/source/autori:Iurescia S., Seripa D., Rinaldi M./titolo:Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants/doi:10.1007%2Fs12035-015-9409-6/rivista:Molecular neurobiology (Online)/anno:2016/pagina_da:5510/pagina_a:5526/intervallo_pagine:5510–5526/volume:53
The serotonin (5-hydroxytriptamine (5-HT)) transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) is a variable number tandem repeats (VNTR) located in the promoter region of the human 5-HTT-encoding gene SLC6A4. This length polymorphism gives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87ef9d0fc8aa2447a69c51dcd427892
https://publications.cnr.it/doc/347049
https://publications.cnr.it/doc/347049
Publikováno v:
ResearcherID
Optimally designed cancer vaccines should combine the best tumor antigens with the most effective immunotherapy agents and delivery strategies to achieve positive clinical results. The unique immunoglobulin (Ig) idiotype on the surface of each B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e366eec8a1988a7d4ef048e2f2d894a7
https://doi.org/10.2174/156652311797415863
https://doi.org/10.2174/156652311797415863
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
Journal of Biomedicine and Biotechnology
2010 (2010): 174378. doi:10.1155/2010/174378
info:cnr-pdr/source/autori:Fioretti D.1*; Iurescia S.1*; Fazio V. M.2,3; Rinaldi M.1 (*first co-authorship)/titolo:DNA vaccines: developing new strategies against cancer/doi:10.1155%2F2010%2F174378/rivista:Journal of Biomedicine and Biotechnology (Print)/anno:2010/pagina_da:174378/pagina_a:/intervallo_pagine:174378/volume:2010
Journal of Biomedicine and Biotechnology
2010 (2010): 174378. doi:10.1155/2010/174378
info:cnr-pdr/source/autori:Fioretti D.1*; Iurescia S.1*; Fazio V. M.2,3; Rinaldi M.1 (*first co-authorship)/titolo:DNA vaccines: developing new strategies against cancer/doi:10.1155%2F2010%2F174378/rivista:Journal of Biomedicine and Biotechnology (Print)/anno:2010/pagina_da:174378/pagina_a:/intervallo_pagine:174378/volume:2010
Due to their rapid and widespread development, DNA vaccines have entered into a variety of human clinical trials for vaccines against various diseases including cancer. Evidence that DNA vaccines are well tolerated and have an excellent safety profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90bb3581545a81e2e5d61da057d852ea
https://doi.org/10.1155/2010/174378
https://doi.org/10.1155/2010/174378
Publikováno v:
Topics in Anti-Cancer Research, pp. 747–794. Oak Park, IL: Bentham Science Publisher, 2015
info:cnr-pdr/source/autori:Daniela Fioretti, Sandra Iurescia and Monica Rinaldi/titolo:The Rationale of Immunogenic and Effective Naked DNA Vaccines Against Cancer: Latest Advances/titolo_volume:Topics in Anti-Cancer Research/curatori_volume:/editore: /anno:2015
info:cnr-pdr/source/autori:Daniela Fioretti, Sandra Iurescia and Monica Rinaldi/titolo:The Rationale of Immunogenic and Effective Naked DNA Vaccines Against Cancer: Latest Advances/titolo_volume:Topics in Anti-Cancer Research/curatori_volume:/editore: /anno:2015
A variety of clinical trials for vaccines against cancer have provided evidence that DNA vaccines are well tolerated and have an excellent safety profile. DNA vaccines require much improvement to make them sufficiently effective against cancer in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09057252b41f041ae624b8a0e36ef7b
https://publications.cnr.it/doc/348626
https://publications.cnr.it/doc/348626