Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Sandra I. Anjo"'
Autor:
Cátia Santa, Diana Rodrigues, Joana F. Coelho, Sandra I. Anjo, Vera M. Mendes, Diogo Bessa-Neto, Michael J. Dunn, David Cotter, Graça Baltazar, Patrícia Monteiro, Bruno Manadas
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Striatal dysfunction has been implicated in the pathophysiology of schizophrenia, a disorder characterized by positive symptoms such as hallucinations and delusions. Haloperidol is a typical antipsychotic medication used in the treatment of
Externí odkaz:
https://doaj.org/article/7414de2ea7014d4ebee8488a19a3acaf
Autor:
Sandra I. Anjo, Zhicheng He, Zohaib Hussain, Aruba Farooq, Alan McIntyre, Charles A. Laughton, Andreia Neves Carvalho, Mattéa J. Finelli
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 681 (2024)
Oxidation–reduction post-translational modifications (redox-PTMs) are chemical alterations to amino acids of proteins. Redox-PTMs participate in the regulation of protein conformation, localization and function, acting as signalling effectors that
Externí odkaz:
https://doaj.org/article/1adcba06898f4926b93ea5ec5a823183
Autor:
Rita I. Pacheco, Maria I. Cristo, Sandra I. Anjo, Andreia F. Silva, Maria Inês Sousa, Renata S. Tavares, Ana Paula Sousa, Teresa Almeida Santos, Mariana Moura-Ramos, Francisco Caramelo, Bruno Manadas, João Ramalho-Santos, Sandra Gomes Amaral
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1462 (2023)
The global trend of rising (male) infertility is concerning, and the unidentifiable causes in half of the cases, the so-called unknown origin male infertility (UOMI), demands a better understanding and assessment of both external/internal factors and
Externí odkaz:
https://doaj.org/article/f16c208205e149bc84850f103ae30f29
Autor:
Margarida Coelho, João Capela, Sandra I. Anjo, João Pacheco, Margarida Sá Fernandes, Isabel Amendoeira, John G. Jones, Luís Raposo, Bruno Manadas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14542 (2023)
Differentiated thyroid cancer is the most common malignancy of the endocrine system. Although most thyroid nodules are benign, given the high incidence of thyroid nodules in the population, it is important to understand the differences between benign
Externí odkaz:
https://doaj.org/article/dc46729911d845778221c331eb3c22d2
Autor:
Margarida Beatriz, Rita Vilaça, Sandra I. Anjo, Bruno Manadas, Cristina Januário, A. Cristina Rego, Carla Lopes
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 10, Pp n/a-n/a (2022)
Abstract Mitochondrial and autophagy dysfunction are mechanisms proposed to be involved in the pathogenesis of several neurodegenerative diseases. Huntington's disease (HD) is a progressive neurodegenerative disorder associated with mutant Huntingtin
Externí odkaz:
https://doaj.org/article/0e8c530454d344a98431b594c545a417
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1072 (2023)
Theragnostics is a promising approach that integrates diagnostics and therapeutics into a single personalized strategy. To conduct effective theragnostic studies, it is essential to create an in vitro environment that accurately reflects the in vivo
Externí odkaz:
https://doaj.org/article/1ad04f6b035546698bc8106c71112283
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102283- (2022)
Efforts have been made to understand the physiological and pathological role of DJ-1, a Parkinson’s disease (PD)-associated protein, to provide new insights into PD pathophysiology. Such studies have revealed several neuroprotective roles of DJ-1,
Externí odkaz:
https://doaj.org/article/ef7772abe84742e498902b3447284435
Autor:
Joana M. S. Cardoso, Sandra I. Anjo, Bruno Manadas, Hugo Silva, Isabel Abrantes, Katsunori Nakamura, Luís Fonseca
Publikováno v:
Frontiers in Plant Science, Vol 12 (2022)
The pinewood nematode (PWN), Bursaphelenchus xylophilus, one of the most serious forest pests worldwide, is considered the causal agent of the pine wilt disease (PWD). The main host species belong to the genus Pinus, and a variation in the susceptibi
Externí odkaz:
https://doaj.org/article/78b0b758a4b2423baf4c1e4275ab2077
Autor:
Sandra I. Anjo, Patrícia Valério dos Santos, Luiza Rosado, Graça Baltazar, Inês Baldeiras, Diana Pires, Andreia Gomes, Cristina Januário, Miguel Castelo-Branco, Mário Grãos, Bruno Manadas
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-14 (2020)
Abstract Background The identification of circulating biomarkers that closely correlate with Parkinson’s Disease (PD) has failed several times in the past. Nevertheless, in this pilot study, a translational approach was conducted, allowing the eval
Externí odkaz:
https://doaj.org/article/8393de978cc645d984e7c48fcb444a26
Autor:
Ana Filipa Fernandes, Luís Gafeira Gonçalves, Maria Bento, Sandra I. Anjo, Bruno Manadas, Clara Barroso, Miguel Villar, Rita Macedo, Maria João Simões, Ana Varela Coelho
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13733 (2022)
Tuberculosis (TB) is a transmissible disease listed as one of the 10 leading causes of death worldwide (10 million infected in 2019). A swift and precise diagnosis is essential to forestall its transmission, for which the discovery of effective diagn
Externí odkaz:
https://doaj.org/article/bbd2adc5f39347c6955452be4390bcde