Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sandra I Grijalva"'
Autor:
Jin-mo Gu, Sandra I. Grijalva, Natasha Fernandez, Elizabeth Kim, D. Brian Foster, Hee Cheol Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Heart health: understanding pacemaker cells The heart’s pacemaker cells contain mitochondria that are smaller than average and require less energy than other heart cells, properties that help make them naturally resilient to stress. Cardiac pacemak
Externí odkaz:
https://doaj.org/article/41ab80b3ac45403e87c4103db9c1529c
Autor:
Sandra I. Grijalva, Jin‐mo Gu, Jun Li, Natasha Fernandez, Jinqi Fan, Jung Hoon Sung, Seung Yup Lee, Conner Herndon, Erin M. Buckley, Sung‐Jin Park, Flavio H. Fenton, Hee Cheol Cho
Publikováno v:
Advanced Science, Vol 6, Iss 22, Pp n/a-n/a (2019)
Abstract Every heartbeat originates from a tiny tissue in the heart called the sinoatrial node (SAN). The SAN harbors only ≈10 000 cardiac pacemaker cells, initiating an electrical impulse that captures the entire heart, consisting of billions of c
Externí odkaz:
https://doaj.org/article/087002c9464344d5ae7d42d4f4dc2991
Autor:
Sandra I. Grijalva, Doohwan Jung, Hua Wang, Adam Wang, Hee Cheol Cho, Natasha Fernandez, Jong Seok Park, Gregory V. Junek, Sagar R. Kumashi, Sensen Li
Publikováno v:
IEEE Journal of Solid-State Circuits. 56:2438-2451
This article presents a fully integrated multi-modal CMOS cellular sensor/stimulator array chip with 21 952 pixels and 1568-pixel concurrent readouts, while each array pixel can be independently reconfigured to support three sensing and one stimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::515d3d0a6e6bc2b32b1df2e08b2e8256
https://doi.org/10.1109/jssc.2021.3085571
https://doi.org/10.1109/jssc.2021.3085571
Autor:
Hee Cheol Cho, Natasha Fernandez, Jin mo Gu, Elizabeth H. Kim, D. Brian Foster, Sandra I. Grijalva
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Cardiac pacemaker cells of the sinoatrial node initiate each and every heartbeat. Compared with our understanding of the constituents of their electrical excitation, little is known about the metabolic underpinnings that drive the automaticity of pac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3f40bd06b9a94f01c4ae6363298857
https://doi.org/10.1038/s12276-019-0303-6
https://doi.org/10.1038/s12276-019-0303-6
Autor:
Caroline M. Ajo-Franklin, Sara Tejedor-Sanz, Jong Seok Park, Sandra I. Grijalva, Doohwan Jung, Adam Wang, Hee Cheol Cho, Sagar R. Kumashi, Sensen Li, Hua Wang
Publikováno v:
IEEE transactions on biomedical circuits and systems. 15(2)
The paper presents a 256-pixel CMOS sensor array with in-pixel dual electrochemical and impedance detection modalities for rapid, multi-dimensional characterization of exoelectrogens. The CMOS IC has 16 parallel readout channels, allowing it to perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca85d27c7b766b8089ec267d494dd2a9
https://pubmed.ncbi.nlm.nih.gov/33760741
https://pubmed.ncbi.nlm.nih.gov/33760741
Autor:
Doohwan Jung, Adam Wang, Jong Seok Park, Sandra I. Grijalva, Hua Wang, Sara Tejedor Sanz, Hee Cheol Cho, Sagar R. Kumashi, Caroline M. Ajo-Franklin, Sensen Li
Publikováno v:
ISSCC
Electrochemically active bacteria (exoelectrogens) are a class of microorganisms capable of transferring electrons between intracellular and exocellular environments, which generate or consume electrical currents via multiple biochemical redox reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1581be7713acb4de6b4d8c93d7c60347
https://doi.org/10.1109/isscc19947.2020.9062991
https://doi.org/10.1109/isscc19947.2020.9062991
Autor:
Taiyun Chi, Moez Karim Aziz, Jong Seok Park, Adam Wang, Sensen Li, Hua Wang, Sandra I. Grijalva, Michael N. Sayegh, Hee Cheol Cho
Publikováno v:
Lab on a Chip, 18 (19)
Lab on a chip
Lab on a chip
Cells are complex systems with concurrent multi-physical responses, and cell physiological signals are often encoded with spatiotemporal dynamics and further coupled with multiple cellular activities. However, most existing electronic sensors are onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cc4ef4879ebb9927c68710105a2a3e
https://doi.org/10.1039/c8lc00156a
https://doi.org/10.1039/c8lc00156a
Autor:
Sensen Li, Hua Wang, Adam Wang, Hee Cheol Cho, Doohwan Jung, Sandra I. Grijalva, Jong Seok Park, Sagar R. Kumashi, Gregory V. Junek
Publikováno v:
VLSI Circuits
This paper presents a fully integrated CMOS multi-modal cellular sensor/stimulator array with 21952 multi-modal pixels, 1568 simultaneous parallel readout channels, 16 μm×16 μm pixel pitch for single cell resolution, and 3.6 mm×1.6 mm tissue-leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::992f4a74344863f354b94ae4db5e7a1d
https://doi.org/10.23919/vlsic.2019.8778043
https://doi.org/10.23919/vlsic.2019.8778043
Autor:
Moez Karim Aziz, Taiyun Chi, Jong Seok Park, Hua Wang, Jung Hoon Sung, Hee Cheol Cho, Sandra I. Grijalva, Sensen Li
Publikováno v:
IEEE Trans Biomed Circuits Syst
This paper presents a fully integrated CMOS multimodality joint sensor/stimulator array with 1024 pixels for real-time holistic cellular characterization and drug screening. The proposed system consists of four pixel groups and four parallel signal-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb63c4f6ca95d478a3d7d64003360e4
https://pubmed.ncbi.nlm.nih.gov/29377798
https://pubmed.ncbi.nlm.nih.gov/29377798
Publikováno v:
Circulation. 136
Background: The sinoatrial node (SAN) has intricate architecture, which facilitates the spontaneous action potentials generated from the SAN to pace and drive the neighboring myocardium. We sought to create an engineered SAN that recapitulates the na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461f12f4a938972e68e2931aefc6b633
https://doi.org/10.1161/circ.136.suppl_1.24057
https://doi.org/10.1161/circ.136.suppl_1.24057