Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandra Huygen"'
Autor:
Olga Golubnitschaja, Bettina Zippel-Schultz, Emilio Vanoli, Frank Heemskerk, Peter Ruff, Thom Hoedemakers, Thomas M. Helms, Judita Kinkorova, Ivana Schnur, Tiny Jaarsma, Lutz Fleischhacker, Sandra Huygen Allianses, Jan Ramaekers, Hans-Peter Brunner-La Rocca, Jose Verdu
Publikováno v:
The EPMA Journal, 7:2. Springer
The EPMA Journal
The EPMA Journal
Chronic diseases are the leading causes of morbidity and mortality in Europe, accounting for more than 2/3 of all death causes and 75 % of the healthcare costs. Heart failure is one of the most prominent, prevalent and complex chronic conditions and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919d33c5836b5539cc9314d9c4a0bdb3
https://cris.maastrichtuniversity.nl/en/publications/2456b900-a697-422c-a940-e5a61174b257
https://cris.maastrichtuniversity.nl/en/publications/2456b900-a697-422c-a940-e5a61174b257
Autor:
Marie-Paule Merville, Valérie Benoit, Vincent Bours, Anne-Cécile Hellin, Jacques E. Gielen, Sandra Huygen
Publikováno v:
Oncogene. 19:4787-4794
The tumor suppressor p53 plays a pivotal role in the cellular response to DNA damage as it controls DNA repair, cell cycle arrest and apoptosis. We studied the autoregulation of human p53 gene transcription in colon cancer cell lines. Wild-type p53 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5775b64a2363497a10186ab5bfad71
https://doi.org/10.1038/sj.onc.1203831
https://doi.org/10.1038/sj.onc.1203831
Akademický článek
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Publikováno v:
Haematologica. 90(4)
The maintenance of adequate interactions with the bone marrow (BM) microenvironment is critical to ensure efficient homing of ex vivo-expanded hematopoietic cells. This study was intended to assess adhesion and migration properties of long-term cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de583854e468b54a772e5324cf0248a2
https://pubmed.ncbi.nlm.nih.gov/15820925
https://pubmed.ncbi.nlm.nih.gov/15820925
Publikováno v:
Leukemialymphoma. 44(8)
Using different experimental approaches, it has been established that transplantability of hematopoietic/stem progenitor cells is ineffective during transit through the cell cycle. Although primitive stem cells are responsive to mitogenic stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14a807dba2de188c1a20deb91d99cb4
https://pubmed.ncbi.nlm.nih.gov/12952232
https://pubmed.ncbi.nlm.nih.gov/12952232
Publikováno v:
Blood. 100(8)
Ex vivo expansion of hematopoietic stem/progenitor cells may result in defective engraftment. Human cord blood CD34(+) progenitor cells were synchronized and assayed for adhesion and migration onto fibronectin (Fn) and vascular cell adhesion molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8118657ea1f0da9a3395dae9755335
https://pubmed.ncbi.nlm.nih.gov/12351381
https://pubmed.ncbi.nlm.nih.gov/12351381
Autor:
Olivier Giet, Ivano Di Stefano, André Gothot, Roland Greimers, Dirk R. Van Bockstaele, Sandra Huygen, Yves Beguin
Publikováno v:
Blood
Engraftment of hematopoietic progenitor cells has been shown to decrease during cell cycle transit. We studied cell cycle-associated changes in adhesion and migration of mitotically activated cord blood CD34(+) cells. Migration toward medium conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1bbdb3e7a63363b9ec65625af1dfe2
https://hdl.handle.net/10067/1033690151162165141
https://hdl.handle.net/10067/1033690151162165141
Publikováno v:
Experimental hematology. 29(4)
Objective. Recent studies suggested that trafficking of hematopoietic progenitor cells is related to cell cycle status. We studied whether adhesion of progenitor cells to extracellular matrix proteins was modulated by cell cycle transit. Materials an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7672db0006586332415bd975ec81d337
https://pubmed.ncbi.nlm.nih.gov/11301192
https://pubmed.ncbi.nlm.nih.gov/11301192
Publikováno v:
Experimental Hematology. 28:54-55
Several reports have suggested that engraftment of stem/progenitor cells is decreased during cell cycle transit. This prompted us to study cell cycle-associated changes in adhesion and migration after a 2-day ex vivo culture in SCF, FL and TPO. We pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab4db9263bb776c8bcf5e77e917ee62
https://doi.org/10.1016/s0301-472x(00)00259-9
https://doi.org/10.1016/s0301-472x(00)00259-9
Publikováno v:
Experimental Hematology. 28:55
Changes in adhesion molecule expression and/or function during cell cycle transit may be critical for engraftment of ex vivo expanded stem/progenitor cells. Here, we studied modulation of adhesion and migration of cell-cycle synchronized LTC-IC. Fres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3878b4e89fececc621753269fe756bb6
https://doi.org/10.1016/s0301-472x(00)00260-5
https://doi.org/10.1016/s0301-472x(00)00260-5