Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandra Hoffarth"'
Autor:
Frank Breitenbuecher, Sandra Hoffarth, Karl Worm, Diana Cortes-Incio, Thomas C Gauler, Jens Köhler, Thomas Herold, Kurt Werner Schmid, Lutz Freitag, Stefan Kasper, Martin Schuler
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85350 (2014)
BACKGROUND: Oncogenic mutations are powerful predictive biomarkers for molecularly targeted cancer therapies. For mutation detection patients have to undergo invasive tumor biopsies. Alternatively, archival samples are used which may no longer reflec
Externí odkaz:
https://doaj.org/article/7f0a02671f7148c3b3d30a83fe7b677b
Autor:
Yvonne Höhn, Martin Schuler, Melanie Guyot, Johannes Meiler, Emmanuelle Wesarg, Sandra Hoffarth, Frank Breitenbuecher
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 138:1385-1394
To investigate the combination of conventional cytotoxic anticancer agents and a small molecule kinase inhibitor in preclinical models of non-small-cell lung cancer (NSCLC). We compared the induction of apoptosis by DNA-damaging anticancer drugs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dda513d9cce1761eeed9356c2613e4
https://doi.org/10.1007/s00432-012-1220-4
https://doi.org/10.1007/s00432-012-1220-4
Autor:
Frank Breitenbuecher, Silvan Becker, Boyka Markova, Martin Schuler, Lars Hennig Schmidt, Rainer Wiewrodt, Sina Pleiner, Patricia S. Hähnel, Sandra Hoffarth
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 6(12)
Introduction: The oxidoreductase WWOX was initially described as a putative tumor suppressor in breast cancer. Non-small cell lung cancers (NSCLCs) frequently show aberrant WWOX expression. Herein, we characterized WWOX at a functional level in precl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e5b2abe610509615e14e7783683f23
https://pubmed.ncbi.nlm.nih.gov/21892104
https://pubmed.ncbi.nlm.nih.gov/21892104
Autor:
Florian Grabellus, Claudia Stolz, Kurt Werner Schmid, Patricia S. Hähnel, Martin Schuler, Sandra Hoffarth, Georg Hess
Publikováno v:
Blood. 112(8)
The chimeric monoclonal antibody rituximab is the standard of care for patients with B-cell non-Hodgkin lymphoma (B-NHL). Rituximab mediates complementdependent cytotoxicity and antibodydependent cellular cytotoxicity of CD20-positive human B cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f76c26bf000eb8a0c898f30ce305e7
https://pubmed.ncbi.nlm.nih.gov/18689543
https://pubmed.ncbi.nlm.nih.gov/18689543
Autor:
J. Abu-Jawad, S. Ting, J. Markowetz, Sven Brandau, M. Schuler, I. Vossebein, Stefan Kasper, Stephan Lang, Thomas Gauler, Christoph Bergmann, Michael Pogorzelski, K.W. Schmid, F. Breitenbücher, Sandra Hoffarth
Publikováno v:
Oral Oncology. 51:e39
Introduction Monoclonal antibodies and tyrosine kinase inhibitors (TKI) targeting the EGFR are approved or under investigation for the systemic treatment of patients with HNSCC. However, primary and acquired resistance against EGFR-targeted therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffaa652330cb466ba61e50982d1b6bb
https://doi.org/10.1016/j.oraloncology.2015.02.040
https://doi.org/10.1016/j.oraloncology.2015.02.040
Autor:
Stefan Kasper, Patricia S. Hähnel, Katja Merches, Frank Breitenbuecher, Halime Kalkavan, Karl S. Lang, Martin Schuler, Sandra Hoffarth, H Schild, C Göbel
Publikováno v:
Cell Death & Disease
The efficacy of immune surveillance and antigen-specific cancer immunotherapy equally depends on the activation of a sustained immune response targeting cancer antigens and the susceptibility of cancer cells to immune effector mechanisms. Using funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72a3004c4c9e259212d437514bf553c
http://europepmc.org/articles/PMC4649842
http://europepmc.org/articles/PMC4649842
Autor:
Stephan Lang, Frank Breitenbuecher, Christoph Bergmann, Jehad Abu Jawad, I. Vossebein, J. Markowetz, Stefan Kasper, Sven Brandau, Kurt Werner Schmid, Martin Schuler, Thomas Gauler, Sandra Hoffarth, Michael Pogorzelski, Saskia Ting
Publikováno v:
Cell Death & Disease
Infection with human papillomaviruses (HPVs) characterizes a distinct subset of head and neck squamous cell cancers (HNSCCs). HPV-positive HNSCC preferentially affect the oropharynx and tonsils. Localized HPV-positive HNSCCs have a favorable prognosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0da19649f2a6eacc0a8ccec31aee91
https://doi.org/10.1038/cddis.2014.62
https://doi.org/10.1038/cddis.2014.62
Autor:
Boyka Markova, Sandra Hoffarth, Florian H. Heidel, Stefan Kasper, Frank Breitenbuecher, Thomas Fischer, Martin Schuler
Publikováno v:
Blood Cancer Journal
Patients suffering from acute myeloid leukemias (AML) bearing FMS-like tyrosine kinase-3-internal tandem duplications (FLT3-ITD) have poor outcomes following cytarabine- and anthracyclin-based induction therapy. To a major part this is attributed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d067a23e073154d8b3a6a8ee6fcc973
http://europepmc.org/articles/PMC3317524
http://europepmc.org/articles/PMC3317524