Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Sandra Hervás‐Stubbs"'
Autor:
Leyre Ayerra, Miguel Angel Abellanas, Leyre Basurco, Ibon Tamayo, Enrique Conde, Adriana Tavira, Amaya Trigo, Clara Vidaurre, Amaia Vilas, Patxi San Martin-Uriz, Esther Luquin, Pedro Clavero, Elisa Mengual, Sandra Hervás-Stubbs, Maria S. Aymerich
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Glial cells are key players in the initiation of innate immunity in neurodegeneration. Upon damage, they switch their basal activation state and acquire new functions in a context and time-dependent manner. Since modulation of neuroinflammat
Externí odkaz:
https://doaj.org/article/5fe591e290234b398623ebc343d1cb63
Autor:
Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, Juan Roberto Rodriguez-Madoz, Jesús San Miguel, Lorea Jordana
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Adoptive cell therapy using genetically modified T cells to express chimeric antigen receptors (CAR-T) has shown encouraging results, particularly in certain blood cancers. Nevertheless, over 40% of B cell malignancy patients experience a
Externí odkaz:
https://doaj.org/article/9476ec368d284e2c9962de6926e355ea
Autor:
Leyre Ayerra, Miguel Angel Abellanas, Leyre Basurco, Adriana Tavira, Esther Luquin, Amaya Vilas, Ibon Tamayo, Mikel Hernaez, Pedro Clavero, Elisa Mengual, Sandra Hervás-Stubbs, Maria S. Aymerich
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S268- (2023)
Externí odkaz:
https://doaj.org/article/194545004e734346ab99981d4c930c16
Autor:
Adriana Tavira, Leyre Basurco, Miguel Angel Abellanas, Leyre Ayerra, Rodrigo Vinueza-Gavilanes, Esther Luquin, Lucia Marrodan, Marta M. Alonso, Pedro Clavero, Elisa Mengual, Monserrat Arrasate, Sandra Hervás-Stubbs, Maria S. Aymerich
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S291-S292 (2023)
Externí odkaz:
https://doaj.org/article/3c4663e1af7b49ac81a0ccf347b4b790
Autor:
Flor Navarro, Noelia Casares, Celia Martín-Otal, Aritz Lasarte-Cía, Marta Gorraiz, Patricia Sarrión, Diana Llopiz, David Reparaz, Nerea Varo, Juan Roberto Rodriguez-Madoz, Felipe Prosper, Sandra Hervás-Stubbs, Teresa Lozano, Juan José Lasarte
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The high metabolic activity and insufficient perfusion of tumors leads to the acidification of the tumor microenvironment (TME) that may inhibit the antitumor T cell activity. We found that pharmacological inhibition of the acid loader chloride/bicar
Externí odkaz:
https://doaj.org/article/dfa52afd638448c3b908195abc57de8d
Autor:
Belén Aparicio, David Repáraz, Marta Ruiz, Diana Llopiz, Leyre Silva, Enric Vercher, Patrick Theunissen, Ibon Tamayo, Cristian Smerdou, Ana Igea, Marta Santisteban, Cristina Gónzalez-Deza, Juan J. Lasarte, Sandra Hervás-Stubbs, Pablo Sarobe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune checkpoint inhibitor (ICI)-based immunotherapy in triple negative breast cancer (TNBC) is achieving limited therapeutic results, requiring the development of more potent strategies. Combination of ICI with vaccination strategies would enhance
Externí odkaz:
https://doaj.org/article/3a2ee2360ef7461b9bdbb51a0147e8e8
Autor:
David Repáraz, Marta Ruiz, Leyre Silva, Belén Aparicio, Josune Egea, Elizabeth Guruceaga, Daniel Ajona, Yaiza Senent, Enrique Conde, Flor Navarro, Sergio Barace, Diego Alignani, Sandra Hervás-Stubbs, Juan José Lasarte, Diana Llopiz, Pablo Sarobe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Vaccination using optimized strategies may increase response rates to immune checkpoint inhibitors (ICI) in some tumors. To enhance vaccine potency and improve thus responses to ICI, we analyzed the gene expression profile of an immunosuppressive den
Externí odkaz:
https://doaj.org/article/53cc78736e214f2f9fa14856330d5191
Autor:
Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design
Externí odkaz:
https://doaj.org/article/c301abd4787842b988871048df0364f6
Autor:
Kathrin Heim, Maike Hofmann, Robert Thimme, Marta Ruiz, Pablo Sarobe, Sandra Hervás-Stubbs, Bruno Sangro, Luigi Buonaguro, Beatrice Cavalluzzo, Angela Mauriello, Maria Tagliamonte, David Repáraz, Enric Vercher, Diana Llopiz, Leyre Silva, Belén Aparicio, Josune Egea, Ibon Tamayo-Uria, Jorge García-Balduz, Carla Castro, Mercedes Iñarrairaegui, Charlotte Rohrer, Catrin Tauber
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Neoantigens, new immunogenic sequences arising from tumor mutations, have been associated with response to immunotherapy and are considered potential targets for vaccination. Hepatocellular carcinoma (HCC) is a moderately mutated tumor, wh
Externí odkaz:
https://doaj.org/article/e75aa63eaad841d5bb0638f521590de1
Autor:
Sandra Hervás-Stubbs, Julián Pardo, Gloria González-Aseguinolaza, Noelia Casares, Iratxe Uranga-Murillo, Juan Lasarte, Uxua Mancheno, Enrique Conde, Enric Vercher, Marta Soria-Castellano, Jesús Suarez-Olmos, Edurne Elizalde, M Luis Rodriguez, Estefanía Rodríguez-García, Mirja Hommel, Gorka Alkorta
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/d555a98505d44ae688231f35b94f7fd2