Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Sandra H. Vaz"'
Autor:
Sara Costa-Pinto, Joana Gonçalves-Ribeiro, Joana Tedim-Moreira, Renato Socodato, João B. Relvas, Ana M. Sebastião, Sandra H. Vaz
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106435- (2024)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, involving the selective degeneration of cortical upper synapses in the primary motor cortex (M1). Excitotoxicity in ALS occurs due to an imbalance between excitation and inhibition,
Externí odkaz:
https://doaj.org/article/3d9bf21c7b474c4fb4d5c69222424290
Autor:
Daniela Sofia Abreu, Joana I. Gomes, Filipa F. Ribeiro, Maria J. Diógenes, Ana M. Sebastião, Sandra H. Vaz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Astrocytes, the most abundant glial cells in the central nervous system (CNS), sense synaptic activity and respond through the release of gliotransmitters, a process mediated by intracellular Ca2+ level changes and SNARE-dependent mechanisms. Ionotro
Externí odkaz:
https://doaj.org/article/88bc3662c30d41e48db116c7ad3c61d4
Autor:
João Moreira, Sónia Santos, Raúl Oliveira, Francisca Silva, Matteo Gava, Ana Vaz, Dora Brites, Margarida Silva, André Simão, Sandra H. Vaz, Rui Rodrigues, Ana Sebastião, Rui Castro, Sara Xapelli, Susana Solá
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S190-S191 (2023)
Externí odkaz:
https://doaj.org/article/e5a6c99e719f426eae08a172cc21badf
Autor:
Joana Gonçalves-Ribeiro, Oksana Savchak, Sara Costa-Pinto, Rafael Sebastian, Alejandro Lillo, Gemma Navarro-Brugal, Rafael Franco, Ana Sebastião, Sandra H. Vaz
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S228-S229 (2023)
Externí odkaz:
https://doaj.org/article/5cb08a8d6b2b4d3ca8280ec3ae126804
Autor:
Mariana Neuparth-Sottomayor, Carolina C. Pina, Tatiana P. Morais, Miguel Farinha-Ferreira, Daniela Sofia Abreu, Filipa Solano, Francisco Mouro, Mark Good, Ana Maria Sebastião, Giuseppe Di Giovanni, Vincenzo Crunelli, Sandra H. Vaz
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106275- (2023)
Typical absence seizures (ASs) are brief periods of lack of consciousness, associated with 2.5–4 Hz spike-wave discharges (SWDs) in the EEG, which are highly prevalent in children and teenagers. The majority of probands in these young epileptic coh
Externí odkaz:
https://doaj.org/article/d8a29053597b48ac852afe512322526d
Autor:
José D. Carvalho-Rosa, Nádia C. Rodrigues, Armando Silva-Cruz, Sandra H. Vaz, Diana Cunha-Reis
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Non-epileptic seizures are identified as a common epileptogenic trigger. Early metaplasticity following seizures may contribute to epileptogenesis by abnormally altering synaptic strength and homeostatic plasticity. We now studied how in vitro epilep
Externí odkaz:
https://doaj.org/article/08f32313eefa42089292bbe6629d4a14
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Neuronal regeneration in the central nervous system (CNS) is an important field of research with relevance to all types of neuronal injuries, including neurodegenerative diseases. The glial scar is a result of the astrocyte response to CNS injury. It
Externí odkaz:
https://doaj.org/article/0abda282f4134c83b8edd2e177f397e2
Autor:
João Conde, Ruth A. Pumroy, Charlotte Baker, Tiago Rodrigues, Ana Guerreiro, Bárbara B. Sousa, Marta C. Marques, Bernardo P. de Almeida, Sohyon Lee, Elvira P. Leites, Daniel Picard, Amrita Samanta, Sandra H. Vaz, Florian Sieglitz, Maike Langini, Marc Remke, Rafael Roque, Tobias Weiss, Michael Weller, Yuhang Liu, Seungil Han, Francisco Corzana, Vanessa A. Morais, Cláudia C. Faria, Tânia Carvalho, Panagis Filippakopoulos, Berend Snijder, Nuno L. Barbosa-Morais, Vera Y. Moiseenkova-Bell, Gonçalo J. L. Bernardes
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 868-881 (2021)
Externí odkaz:
https://doaj.org/article/13e41edb1f1f40069a060c39b209935b
Autor:
Catarina B. Ferreira, Mikael Marttinen, Joana E. Coelho, Kaisa M.A. Paldanius, Mari Takalo, Petra Mäkinen, Luukas Leppänen, Catarina Miranda-Lourenço, João Fonseca-Gomes, Sara R. Tanqueiro, Sandra H. Vaz, Rita F. Belo, Ana Maria Sebastião, Ville Leinonen, Hilkka Soininen, Ian Pike, Annakaisa Haapasalo, Luísa V. Lopes, Alexandre de Mendonça, Maria José Diógenes, Mikko Hiltunen
Publikováno v:
Neurobiology of Disease, Vol 163, Iss , Pp 105603- (2022)
Alzheimer's disease (AD) is the most common form of dementia, which is neuropathologically characterized by extracellular senile plaques containing amyloid-β and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Prev
Externí odkaz:
https://doaj.org/article/64ca49ebf34d4f8fba3b77430bcc78cd
Autor:
Marta Barbosa, Cátia Gomes, Catarina Sequeira, Joana Gonçalves-Ribeiro, Carolina Campos Pina, Luís A. Carvalho, Rui Moreira, Sandra H. Vaz, Ana Rita Vaz, Dora Brites
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Reactive astrocytes in Amyotrophic Lateral Sclerosis (ALS) change their molecular expression pattern and release toxic factors that contribute to neurodegeneration and microglial activation. We and others identified a dysregulated inflammatory miRNA
Externí odkaz:
https://doaj.org/article/42771c50c3fa4e2396ce40ccf6654bad