Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sandra Gohrbandt"'
Autor:
Jessica Bogs, Jutta Veits, Sandra Gohrbandt, Jana Hundt, Olga Stech, Angele Breithaupt, Jens P Teifke, Thomas C Mettenleiter, Jürgen Stech
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11826 (2010)
Highly pathogenic avian influenza viruses (HPAIV) originate from avirulent precursors but differ from all other influenza viruses by the presence of a polybasic cleavage site in their hemagglutinins (HA) of subtype H5 or H7. In this study, we investi
Externí odkaz:
https://doaj.org/article/bc6a14a9876943428165c6416770d2f9
Autor:
Sandra Gohrbandt, Jürgen Stech, Jens Peter Teifke, Angele Breithaupt, Jutta Veits, Mario Ziller, Elsayed M. Abdelwhab, Thomas C. Mettenleiter
Highly pathogenic (HP) avian influenza viruses (AIV) evolve from low pathogenic (LP) precursors after circulation in poultry by reassortment and/or single mutations in different gene segments including that encoding NS1. The carboxyl terminal end (CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0709954fc5fb240bbf08eaaf4519e94
https://europepmc.org/articles/PMC5026787/
https://europepmc.org/articles/PMC5026787/
Interindividual variability and co-regulation of DNA methylation differ among blood cell populations
Publikováno v:
Epigenetics. 7:1421-1434
DNA methylation regulates gene expression in a cell-type specific way. Although peripheral blood mononuclear cells (PBMCs) comprise a heterogeneous cell population, most studies of DNA methylation in blood are performed on total mononuclear cells. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e58cf69c0a491e21054f66d6b5a216
https://doi.org/10.4161/epi.22845
https://doi.org/10.4161/epi.22845
Autor:
Jutta Veits, Sandra Gohrbandt, Jana Hundt, Jessica Bogs, Jürgen Stech, Jens Peter Teifke, Marcus Gräber, Thomas C. Mettenleiter, Olga Stech, Angele Breithaupt, Siegfried Weber
Publikováno v:
Proceedings of the National Academy of Sciences. 109:2579-2584
High-pathogenic avian influenza viruses (HPAIVs) evolve from low-pathogenic precursors specifying the HA serotypes H5 or H7 by acquisition of a polybasic HA cleavage site. As the reason for this serotype restriction has remained unclear, we aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3fbdf8ceb35222d7cc10027398e41a
https://doi.org/10.1073/pnas.1109397109
https://doi.org/10.1073/pnas.1109397109
Autor:
Angele Breithaupt, Thomas C. Mettenleiter, Sandra Gohrbandt, Siegfried Weber, Jana Hundt, Jessica Bogs, Jens Peter Teifke, Jutta Veits, Jürgen Stech
Publikováno v:
Journal of General Virology. 92:51-59
The prime virulence determinant of highly pathogenic avian influenza viruses (HPAIVs) is the polybasic haemagglutinin (HA) cleavage site. However, engineering of a polybasic cleavage site into an avian influenza virus of low pathogenicity does not re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec69311144b789064a675b73e5e4a9d8
https://doi.org/10.1099/vir.0.023887-0
https://doi.org/10.1099/vir.0.023887-0
Autor:
Carsten Krohmann, Sandra Gohrbandt, Benjamin Schusser, Jana Hundt, Dennis Rubbenstroth, Nicola Penski, Georg Kochs, Sonja Härtle, Thomas W. Vahlenkamp, Bernd Kaspers, Angele Breithaupt, Antje Reuter, Artur Summerfield, Nicolas Ruggli, Jürgen Stech, Jutta Veits, Peter Staeheli, Michael Pfann
Publikováno v:
Journal of virology. 85(15)
From infection studies with cultured chicken cells and experimental mammalian hosts, it is well known that influenza viruses use the nonstructural protein 1 (NS1) to suppress the synthesis of interferon (IFN). However, our current knowledge regarding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c3fbf11d1e1876560adfadbbb8d6e1
https://pubmed.ncbi.nlm.nih.gov/21613402
https://pubmed.ncbi.nlm.nih.gov/21613402
Autor:
Olga Stech, Thomas C. Mettenleiter, Angele Breithaupt, Sandra Gohrbandt, Jens Peter Teifke, Jana Hundt, Jutta Veits, Jürgen Stech
Publikováno v:
The Journal of general virology. 92(Pt 8)
In the field, highly pathogenic avian influenza viruses (HPAIV) originate from low-pathogenic strains of the haemagglutinin (HA) serotypes H5 and H7 that have acquired a polybasic HA cleavage site. This observation suggests the presence of a cryptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372474b1e5d0edb57ab1426fe56f82a9
https://pubmed.ncbi.nlm.nih.gov/21525207
https://pubmed.ncbi.nlm.nih.gov/21525207
Autor:
Angele Breithaupt, Jessica Bogs, Jens Peter Teifke, Jutta Veits, Sandra Gohrbandt, Thomas C. Mettenleiter, Jürgen Stech, Jana Hundt, Olga Stech
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11826 (2010)
PLoS ONE, Vol 5, Iss 7, p e11826 (2010)
Highly pathogenic avian influenza viruses (HPAIV) originate from avirulent precursors but differ from all other influenza viruses by the presence of a polybasic cleavage site in their hemagglutinins (HA) of subtype H5 or H7. In this study, we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a2264720616e532cdc88bfdd064a7f
https://pubmed.ncbi.nlm.nih.gov/20676399
https://pubmed.ncbi.nlm.nih.gov/20676399
Autor:
Jürgen Stech, Sandra Gohrbandt, Hans-Dieter Klenk, Anne Kreibich, Siegfried Weber, Astrid Herwig, Hermann C. Altmeppen, Thomas C. Mettenleiter, Olga Stech, Jana Hundt
Publikováno v:
Nucleic Acids Research
Reverse genetics has become pivotal in influenza virus research relying on rapid generation of tailored recombinant influenza viruses. They are rescued from transfected plasmids encoding the eight influenza virus gene segments, which have been cloned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed490c28dc51c50aeea73e1e827fa91
https://doi.org/10.1093/nar/gkn646
https://doi.org/10.1093/nar/gkn646