Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sandra Gómez-López"'
Autor:
Elizabeth F. Maughan, Robert E. Hynds, Adam Pennycuick, Ersilia Nigro, Kate H.C. Gowers, Celine Denais, Sandra Gómez-López, Kyren A. Lazarus, Jessica C. Orr, David R. Pearce, Sarah E. Clarke, Dani Do Hyang Lee, Maximillian N.J. Woodall, Tereza Masonou, Katie-Marie Case, Vitor H. Teixeira, Benjamin E. Hartley, Richard J. Hewitt, Chadwan Al Yaghchi, Gurpreet S. Sandhu, Martin A. Birchall, Christopher O’Callaghan, Claire M. Smith, Paolo De Coppi, Colin R. Butler, Sam M. Janes
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105409- (2022)
Summary: The airway epithelium is a protective barrier that is maintained by the self-renewal and differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung diseases, but few studies have explored age-related mole
Externí odkaz:
https://doaj.org/article/bc9bfc65a4564f5b8c32bca349dccceb
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Gómez-López and co-authors discuss advances in the development of in vitro and in vivo models for lung squamous cell carcinoma (LUSC) and their role in understanding the cellular and molecular processes driving LUSC development and responses to the
Externí odkaz:
https://doaj.org/article/2d936ce2a63244909d5cd1039e1cd7e0
Autor:
Kim B. Jensen, Sandra Gómez-López, Adam Pennycuick, Ahmed S. N. Alhendi, Laura Succony, Derek Davies, Kate H.C. Gowers, Nicholas A. Wright, Sam M. Janes, Sarah E. Clarke
Publikováno v:
Succony, L, Gómez-López, S, Pennycuick, A, Alhendi, A S N, Davies, D, Clarke, S E, Gowers, K H C, Wright, N A, Jensen, K B & Janes, S M 2022, ' Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth ', European Respiratory Journal, vol. 59, 2000816 . https://doi.org/10.1183/13993003.00816-2020
BackgroundLung squamous cell carcinoma (LUSC) accounts for a significant proportion of cancer deaths worldwide, and is preceded by the appearance of progressively disorganised pre-invasive lesions in the airway epithelium. Yet the biological mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bc4b6b060200e4112f574104cd276e
https://curis.ku.dk/portal/da/publications/lrig1-expression-identifies-airway-basal-cells-with-high-proliferative-capacity-and-restricts-lung-squamous-cell-carcinoma-growth(19158daa-0781-4fc7-afb2-694cf6b6c016).html
https://curis.ku.dk/portal/da/publications/lrig1-expression-identifies-airway-basal-cells-with-high-proliferative-capacity-and-restricts-lung-squamous-cell-carcinoma-growth(19158daa-0781-4fc7-afb2-694cf6b6c016).html
Autor:
Teresa Montiel, Daniel Osorio-Gómez, Lourdes Massieu, Diana Escalante-Alcalde, Sandra Gómez-López, Ana Valeria Martínez-Silva, Federico Bermúdez-Rattoni
Publikováno v:
Scientific Reports
Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder, characterised by the progressive loss of midbrain dopaminergic neurons and a variety of motor symptoms. The gene coding for the phospholipid phosphatase 3, PLPP3 (formerly PPA
Autor:
Luis Covarrubias, David Hernández-García, Susana Castro-Obregón, Concepción Valencia, Sandra Gómez-López
Publikováno v:
Experimental Cell Research. 314:2090-2099
The formation of the proamniotic cavity is the first indication of programmed cell death associated to a morphogenetic process in mammals. Although some growth factors have been implicated in proamniotic cavitation, very little is known about the int
Autor:
Rolf Kemler, Jason Wray, T. Kalkan, Dominik Eckardt, Andrew Simon Cook, Sandra Gómez-López, Austin Smith
Publikováno v:
Nature Cell Biology
Nature cell biology
Nature Cell Biology; Vol 13
Nature cell biology
Nature Cell Biology; Vol 13
Self-renewal of rodent embryonic stem cells is enhanced by partial inhibition of glycogen synthase kinase-3 (Gsk3; refs 1, 2). This effect has variously been attributed to stimulation of Wnt signalling by β-catenin, stabilization of Myc protein and
Autor:
Austin Smith, Rebecca Favaro, David Price, Sandra Gómez-López, Steven M. Pollard, Silvia K. Nicolis, Ole Wiskow
Radial-glia-like neural stem (NS) cells may be derived from neural tissues or via differentiation of pluripotent embryonic stem (ES) cells. However, the mechanisms controlling NS cell propagation and differentiation are not yet fully understood. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c0ea972ce801af75a2fbb447e049f2
http://hdl.handle.net/10281/29255
http://hdl.handle.net/10281/29255