Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandra E. Joppé"'
Autor:
Laura K. Hamilton, Gaël Moquin-Beaudry, Chenicka L. Mangahas, Federico Pratesi, Myriam Aubin, Anne Aumont, Sandra E. Joppé, Alexandre Légiot, Annick Vachon, Mélanie Plourde, Catherine Mounier, Martine Tétreault, Karl J. L. Fernandes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Abstract The defining features of Alzheimer’s disease (AD) include alterations in protein aggregation, immunity, lipid metabolism, synapses, and learning and memory. Of these, lipid abnormalities are the least understood. Here, we investigate the r
Externí odkaz:
https://doaj.org/article/c4156f3f019a4fb582af55e7362fab88
Autor:
Laura K. Hamilton, Gaël Moquin-Beaudry, Chenicka L. Mangahas, Federico Pratesi, Myriam Aubin, Anne Aumont, Sandra E. Joppé, Alexandre Légiot, Annick Vachon, Mélanie Plourde, Catherine Mounier, Martine Tétreault, Karl J. L. Fernandes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/9953dc3130f340d693a49140e14e055f
Autor:
Loïc M. Cochard, Louis-Charles Levros, Sandra E. Joppé, Federico Pratesi, Anne Aumont, Karl J. L. Fernandes
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The ventricular-subventricular zone (V-SVZ) is the principal neurogenic niche in the adult mammalian forebrain. Neural stem/progenitor cell (NSPC) activity within the V-SVZ is controlled by numerous of extrinsic factors, whose downstream effects on N
Externí odkaz:
https://doaj.org/article/2c298c0b1ab64c679124a8c30c68d8a4
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9781003339618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73adbcdbebe2be85b1564eda83247b2d
https://doi.org/10.1201/9781003339618-22
https://doi.org/10.1201/9781003339618-22
Autor:
Fanie Barnabé-Heider, Laura K. Hamilton, Anne Aumont, Karl Jl Fernandes, Pierre Ameslon, Loic M. Cochard, Sandra E. Joppé, Louis-Charles Levros
Publikováno v:
Life Science Alliance
In vivo evidence for precursors that produce neurons independent of neurosphere-forming neural stem cells suggests the adult forebrain, like the developing brain, has two distinct neurogenic pathways.
The ventricular epithelium of the adult fore
The ventricular epithelium of the adult fore
Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here
Publikováno v:
European Journal of Neuroscience. 37:1978-1986
In the brains of adult vertebrates, including humans, neurogenesis occurs in restricted niches where it maintains cellular turnover and cognitive plasticity. In virtually all species, however, aging is associated with a significant decline in adult n
Autor:
Martin Parent, Sandra E. Joppé, Karl J.L. Fernandes, Laura K. Hamilton, Pierre Chaurand, Frédéric Calon, Martin Dufresne, Sarah Petryszyn, Anne Aumont, Alexandra Furtos
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Grigorios N Paliouras, Sandra E. Joppé, Fanie Barnabé-Heider, Laura K. Hamilton, Anne Aumont, Karl J.L. Fernandes
Publikováno v:
The Journal of Neuroscience. 32:15012-15026
Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles of key intracellular signaling pathways remain vaguely defined. Here, we show that mammalian
Autor:
Loic M. Cochard, Karl J.L. Fernandes, Sandra E. Joppé, Laura K. Hamilton, Fanie Barnabé-Heider, Louis-Charles Levros, Anne Aumont
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Frontiers in Neuroscience
Frontiers in Neuroscience
A single asymmetric division by an adult neural stem cell (NSC) ultimately generates dozens of differentiated progeny, a feat made possible by the proliferative expansion of transit-amplifying progenitor cells (TAPs). Although NSC activation and TAP
Autor:
Karl J.L. Fernandes, Sarah Petryszyn, Martin Parent, Frédéric Calon, Martin Dufresne, Anne Aumont, Sandra E. Joppé, Pierre Chaurand, Laura K. Hamilton, Alexandra Furtos, Fanie Barnabé-Heider
Publikováno v:
Cell stem cell. 17(4)
SummaryLipid metabolism is fundamental for brain development and function, but its roles in normal and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we uncover a fatty acid-mediated mechanism suppressing endogenous N