Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Sandra E. File"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 82:133-139
The results of two previous studies on the effects of modafinil, a selective wakefulness-promoting agent, in healthy university students were combined in a retrospective analysis. This allowed determination of whether the effects of modafinil were de
Publikováno v:
Psychopharmacology. 179:437-446
Acute doses of Ginkgo biloba have been shown to improve attention and memory in young, healthy participants, but there has been a lack of investigation into possible effects on executive function. In addition, only one study has investigated the effe
Publikováno v:
Pharmacology Biochemistry and Behavior. 78:629-638
Self-ratings of mood and bodily symptoms were made by groups of IQ and education-matched male and female students [teetotal, low (2-9 units/week for both sexes; 1 UK unit=8 g alcohol) and moderate (12-34 units/week for males; 10-24 units/week for fem
Publikováno v:
Psychopharmacology. 177:93-99
Animals trained to lick for a sucrose solution of a given incentive value that subsequently encounter an incentive downshift (i.e. 32-4% sucrose) display an exaggerated decrease in the amount consumed, relative to unshifted controls. This change has
Publikováno v:
Behavioural Pharmacology. 14:323-329
Alpha7 nicotinic acetylcholine receptors (alpha7 nAChRs) and 5-hydroxytryptamine 1A (5-HT1A) receptors have been implicated in the anxiogenic effects of centrally administered nicotine, but the receptors that mediate the anxiogenic effects of systemi
Autor:
David H. Overstreet, Darin J. Knapp, Sandra E. File, Lewis S. Seiden, Richard De la Garza, Randall C. Commissaris
Publikováno v:
Stress: The International Journal on the Biology of Stress. 6:101-110
Clinical studies have suggested the involvement of 5-HT1A receptors in anxiety and depressive disorders because partial 5-HT1A receptor agonists such as buspirone are therapeutic. The present review considers evidence from genetic animal models that
Autor:
Sandra E. File, Mary L. Forsling, Nazmul Alom, Sonia Tucci, Jessica E. Edwards, David E. Hartley, Claire E. Spiller, P. Seth
Publikováno v:
Psychopharmacology. 167:46-53
Most commercial rodent diets are formulated with soya protein and therefore contain soya isoflavones. Isoflavones form one of the main classes of phytoestrogens and have been found to exert both oestrogenic and anti-oestrogenic effects on the central
Autor:
P. Seth, Sandra E. File
Publikováno v:
European Journal of Pharmacology. 463:35-53
The social interaction test of anxiety was developed 25 years ago to provide an ethologically based test that was sensitive to both anxiolytic and anxiogenic effects. It is sensitive to a number of environmental and physiological factors that can aff
Publikováno v:
Neuropsychopharmacology. 28:1257-1263
Anxiety may play a role in the initiation of smoking and there is evidence to suggest that sex and age may predetermine responses to nicotine. At present, the greatest increase in smoking is in women and it is often accompanied by dieting. The purpos
Publikováno v:
Psychopharmacology. 164:309-317
Rationale. Despite its reinforcing properties nicotine has also been reported to produce anxiety in humans and anxiogenic effects in animal tests of anxiety. Objective. The aims of this study were three-fold: (a) to investigate whether anxiety can be