Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sandra Duquesne"'
Autor:
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Cornelius Miething, Uta S. Martens, Khalid Shoumariyeh, Rosa P. Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R. Blazar, Burkhard Becher, Melanie Boerries, Robert Zeiser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Patients with corticosteroid-refractory acute graft-versus-host disease (aGVHD) have a low one-year survival rate. Identification and validation of novel targetable kinases in patients who experience corticosteroid-refractory-aGVHD may help
Externí odkaz:
https://doaj.org/article/cb63dbf7545c4a79898fb5a39c9842f1
Autor:
Lina Mouna, Mehdi Razazian, Sandra Duquesne, Anne-Marie Roque-Afonso, Christelle Vauloup-Fellous
Publikováno v:
Viruses, Vol 15, Iss 2, p 426 (2023)
Vaccination against COVID-19 is the main public health approach to fight against the pandemic. The Spike (S) glycoprotein of SARS-CoV-2 is the principal target of the neutralizing humoral response. We evaluated the analytical and clinical performance
Externí odkaz:
https://doaj.org/article/213842a5f074410a8015dc986e19e14d
Autor:
Shaima’a Hamarsheh, Lena Osswald, Benedikt S. Saller, Susanne Unger, Donatella De Feo, Janaki Manoja Vinnakota, Martina Konantz, Franziska M. Uhl, Heiko Becker, Michael Lübbert, Khalid Shoumariyeh, Christoph Schürch, Geoffroy Andrieux, Nils Venhoff, Annette Schmitt-Graeff, Sandra Duquesne, Dietmar Pfeifer, Matthew A. Cooper, Claudia Lengerke, Melanie Boerries, Justus Duyster, Charlotte M. Niemeyer, Miriam Erlacher, Bruce R. Blazar, Burkard Becher, Olaf Groß, Tilman Brummer, Robert Zeiser
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Oncogenic Ras mutations are common drivers in myeloid leukemia. Here, the authors show in patient cells and in mice that oncogenic K-Ras activates NLRP3 inflammasome to drive myeloproliferation, which can be reversed by genetic or pharmacologic NLRP3
Externí odkaz:
https://doaj.org/article/8d60e15645a540748f0978aece6a6bc5
Autor:
Sobhika Agarwala, Sandra Duquesne, Kun Liu, Anton Boehm, Lin Grimm, Sandra Link, Sabine König, Stefan Eimer, Olaf Ronneberger, Virginie Lecaudey
Publikováno v:
eLife, Vol 4 (2015)
During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo signaling pathway plays a major role in organ growth control, how it senses and responds to increased cell density is still uncle
Externí odkaz:
https://doaj.org/article/9b62c3c4bd69442fbb80be607b64ae55
Autor:
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M. Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M. Woessner, Hans D. Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R. Blazar, Susana Minguet, Patrick Turko, Mitchell P. Levesque, Burkhard Becher, Robert Zeiser
Publikováno v:
Molecular Cancer Research. :OF1-OF16
The treatment of patients with metastatic melanoma with immune checkpoint inhibitors (ICI) leads to impressive response rates but primary and secondary resistance to ICI reduces progression-free survival. Novel strategies that interfere with resistan
Autor:
Robert Zeiser, Burkhard Becher, Mitchell P. Levesque, Patrick Turko, Susana Minguet, Bruce R. Blazar, Tilman Brummer, Melanie Börries, Justus Duyster, Sanaz Taromi, Hans D. Menssen, Nadine M. Woessner, Dietmar Pfeifer, Sandra Duquesne, Geoffroy Andrieux, Lukas M. Braun, Tobias Wertheimer, Lukas Rindlisbacher, Sara Costa-Pereira, Stefan Richtsfeld, Sophie Giesler, Marlene Langenbach
The treatment of patients with metastatic melanoma with immune checkpoint inhibitors (ICI) leads to impressive response rates but primary and secondary resistance to ICI reduces progression-free survival. Novel strategies that interfere with resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f227deb934c8c58d49727aa6c44e18
https://doi.org/10.1158/1541-7786.c.6628382.v1
https://doi.org/10.1158/1541-7786.c.6628382.v1
Autor:
Robert Zeiser, Burkhard Becher, Mitchell P. Levesque, Patrick Turko, Susana Minguet, Bruce R. Blazar, Tilman Brummer, Melanie Börries, Justus Duyster, Sanaz Taromi, Hans D. Menssen, Nadine M. Woessner, Dietmar Pfeifer, Sandra Duquesne, Geoffroy Andrieux, Lukas M. Braun, Tobias Wertheimer, Lukas Rindlisbacher, Sara Costa-Pereira, Stefan Richtsfeld, Sophie Giesler, Marlene Langenbach
Supplementary Figures Legends and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c16a74ced8b40eb135e57100a09850
https://doi.org/10.1158/1541-7786.22743773
https://doi.org/10.1158/1541-7786.22743773
Autor:
Robert Zeiser, Tilman Brummer, Melanie Boerries, Justus Duyster, Annette Schmitt-Graeff, Lukas M. Braun, Sandra Duquesne, Christine Dierks, Claudius Klein, Geoffroy Andrieux, Franziska Maria Uhl, Shaima'a Hamarsheh, Lena Osswald
The bone marrow microenvironment (BMME) is key player in regulation and maintenance of hematopoiesis. Oncogenic RAS mutations, causing constitutive activation of multiple tumor-promoting pathways, are frequently found in human cancer. So far in hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50d9300956a84504938585998fec2dc2
https://doi.org/10.1158/1541-7786.c.6544992.v1
https://doi.org/10.1158/1541-7786.c.6544992.v1
Autor:
Robert Zeiser, Tilman Brummer, Melanie Boerries, Justus Duyster, Annette Schmitt-Graeff, Lukas M. Braun, Sandra Duquesne, Christine Dierks, Claudius Klein, Geoffroy Andrieux, Franziska Maria Uhl, Shaima'a Hamarsheh, Lena Osswald
S1. KrasG12D recipient mice develop a myelodysplastic syndrome within the transferred WT hematopoietic system. S2. Gating strategy used for the isolation of bone marrow (BM) niche cells. S3. The frequency of BM niche cells is not affected in KrasG12D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b3296df9d02a5d90b9267cc3fde8e8
https://doi.org/10.1158/1541-7786.22526058
https://doi.org/10.1158/1541-7786.22526058
Autor:
Robert Zeiser, Melanie Boerries, Frank Meiss, Annette Schmitt-Graeff, Heide Dierbach, Dietmar Pfeifer, Geoffroy Andrieux, Martina Falk, Dominik Schmidt, Sandra Duquesne, Wolfgang Melchinger, Kathrin Hanke, Hana Andrlova, Natalie Stickel, Justin Mastroianni
(S1) Supplemental Figure S1 shows the flow cytometry based analysis of B16 cells transformed with a lentiviral vector with Luc-GFP-neo (S2-S7) Supplemental Figures S2-S7 show complete western blot images (S8) Supplemental Figure S8 shows the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af626e15fb0ad00f4a702f1e8dc82825
https://doi.org/10.1158/0008-5472.22420649
https://doi.org/10.1158/0008-5472.22420649